HOX Genes

HOX Genes PDF Author:
Publisher: Academic Press
ISBN: 0080923127
Category : Science
Languages : en
Pages : 345

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Book Description
A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation. Hox genes can be thought of as general purpose control genes—that is, they are similar in many organisms and direct the same processes in a variety of organisms, from mouse, to fly, to human. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Inclusion of chapters that discuss the evolutionary development of a wide variety of organisms - Gives researchers and clinicians insight into how defective Hox genes trigger developmental abnormalities in embryos

HOX Genes

HOX Genes PDF Author:
Publisher: Academic Press
ISBN: 0080923127
Category : Science
Languages : en
Pages : 345

Get Book Here

Book Description
A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation. Hox genes can be thought of as general purpose control genes—that is, they are similar in many organisms and direct the same processes in a variety of organisms, from mouse, to fly, to human. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Inclusion of chapters that discuss the evolutionary development of a wide variety of organisms - Gives researchers and clinicians insight into how defective Hox genes trigger developmental abnormalities in embryos

Hox Genes

Hox Genes PDF Author: Jean S. Deutsch
Publisher: Springer
ISBN: 9781441966728
Category : Medical
Languages : en
Pages : 0

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Book Description
In his 1894 book, Materials for the Study of Variation, William Bateson coined the term Homoeosis with the following prose: The case of the modification of the antenna of an insect into a foot, of the eye of a Crustacean into an antenna, of a petal into a stamen, and the like, are examples of the same kind. It is desirable and indeed necessary that such Variations, which consist in the assumption by one member of a Meristic series, of the form or characters proper to other members of the series, should be recognized as constituting a distinct group of phenomena. ...I therefore propose...the term HOMOEOSIS...; for the essential phenomenon is not that there has merely been a change, but that something has been changed into the likeness of something else. The book was intended as a listing of the kinds of naturally occurring variation that could act as a substrate for the evolutionary process and Bateson took his examples from collections, both private and in museums, of materials displaying morphological oddities. Interestingly the person who also coined the term “Genetics” proffered little in the way of speculation on the possible genetic underpinnings of these oddities. It wasn’t until the early part of the next century that these changes in meristic series were shown to be heritable.

Guidebook to the Homeobox Genes

Guidebook to the Homeobox Genes PDF Author: Denis Duboule
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 306

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Book Description
This much-needed guidebook provides research workers with the most up-to-date reference available on homeobox genes. As the tenth anniversary of the discovery of the homeobox fast approaches, these genes are being isolated from an ever-widening group of organisms and are now understood as critical to numerous developmental processes. But the rapidly increasing pool of information on homeobox genes has often resulted in a lack of coordination in the use of nomenclature and classification systems. As a result, the field has been sometimes characterized by its confusing and scattered literature. This book provides an overview of the subject by summarizing the dispersed findings and by listing key references. The first two chapters give a brief historical account of the discovery of the homeobox and introduce the reader to its role in development. The third chapter provides comprehensive coverage to the classification and structural organization of the homeobox genes. Finally, short descriptions of individual homeobox genes are provided in alphabetical order at the end of the book. Guidebook to the Homeobox Genes, with its easy-to-use format, offers a quick and simple way to learn about the essentials of each gene with cogent descriptions and helpful references . It will be welcomed by students and professionals in developmental biology, molecular genetics, and molecular biology.

Genes 7

Genes 7 PDF Author: Benjamin Lewin
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 1016

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Book Description
Genes VII gives an integrated and authoritative account of the structure and function of genes. It is thoroughly up to date with the latest research and thinking in the field. Successive editions have provided an integrated account of the whole field of modern molecular genetics and thisedition continues that approach, providing a new synthesis and continuing the greater emphasis on how genes function in their biological context. In a change to all previous editions, which started with a traditional analysis of formal genetics, this seventh edition has been organised to present thesubject in the context of the eukaryotic gene as revealed in the last decade, an analysis based directly on the molecular properties of the gene itself.From the Preface: "The thesis of Genes is that only by understanding the structure and function of the gene itself will we be able in turn to understand the operation of the genome as a whole. Although the emphasis has shifted to the characterization of eukaryotic genes, and therefore to theiranalysis by the direct techniques of molecular biology rather than the subtlety of genetics, the classical approach remains intellectually penetrating. It remains an aim of this book to integrate both approaches in the context of a unified approach to prokaryotes and eukaryotes."

Patterning and Cell Type Specification in the Developing CNS and PNS

Patterning and Cell Type Specification in the Developing CNS and PNS PDF Author:
Publisher: Academic Press
ISBN: 0123973481
Category : Science
Languages : en
Pages : 993

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Book Description
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells

HOX Gene Expression

HOX Gene Expression PDF Author: Spyros Papageorgiou
Publisher: Springer Science & Business Media
ISBN: 0387689907
Category : Medical
Languages : en
Pages : 158

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Book Description
Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.

Hox Genes

Hox Genes PDF Author: Jean S. Deutsch
Publisher: Springer Science & Business Media
ISBN: 1441966730
Category : Medical
Languages : en
Pages : 184

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Book Description
In his 1894 book, Materials for the Study of Variation, William Bateson coined the term Homoeosis with the following prose: The case of the modification of the antenna of an insect into a foot, of the eye of a Crustacean into an antenna, of a petal into a stamen, and the like, are examples of the same kind. It is desirable and indeed necessary that such Variations, which consist in the assumption by one member of a Meristic series, of the form or characters proper to other members of the series, should be recognized as constituting a distinct group of phenomena. ...I therefore propose...the term HOMOEOSIS...; for the essential phenomenon is not that there has merely been a change, but that something has been changed into the likeness of something else. The book was intended as a listing of the kinds of naturally occurring variation that could act as a substrate for the evolutionary process and Bateson took his examples from collections, both private and in museums, of materials displaying morphological oddities. Interestingly the person who also coined the term “Genetics” proffered little in the way of speculation on the possible genetic underpinnings of these oddities. It wasn’t until the early part of the next century that these changes in meristic series were shown to be heritable.

Evolutionary Developmental Biology of Crustacea

Evolutionary Developmental Biology of Crustacea PDF Author: Gerhard Scholtz
Publisher: CRC Press
ISBN: 9789058096371
Category : Science
Languages : en
Pages : 324

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Book Description
Crustaceans, due to the great diversity of their body organization, segmentation patterns, tagmatization, limb types, larval forms, cleavage, and gastrulation modes, are highly desirable for the study of questions at the interface of evolution and development. Modern interest in evolutionary developmental biology (evo-devo) rests on the molecular genetic approach and a variety of molecular techniques have proven fruitful when performed on crustaceans. Evolutionary Developmental Biology of Crustacea presents a comprehensive treatment of all aspects of the field, beginning with a discussion of the implications of the typological Bauplan and phylum concepts versus historical concepts such as ground pattern and monophylum for the formulation of conceptual questions in evo-devo. Following this, the authors present the results of Hox gene expression in various crustacean taxa, aspects of segment formation at the cellular and genetic levels, the formation of segmental structures such as neurons, ganglia, and limbs, and the role of morphological ontogenetic characters in resolving phylogenetic relationships. By covering so many general aspects of crustacean development, morphology, and evolution, Evolutionary Developmental Biology of Crustacea serves as an indispensable reference for developmental and evolutionary biologists investigating the role of genetics in evolution and development.

The Art of Genes

The Art of Genes PDF Author: Enrico Coen
Publisher: Oxford University Press, USA
ISBN: 0192862081
Category : Medical
Languages : en
Pages : 397

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Book Description
In this highly original synthesis of art and science, Enrico Coen describes the recent revolution in human understanding of how plants and animals develop and how this offers fresh insights into evolution and human creativity.

Chance and Necessity

Chance and Necessity PDF Author: Jacques Monod
Publisher:
ISBN: 9780140256468
Category : Biology
Languages : en
Pages : 198

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Book Description
Change and necessity is a statement of Darwinian natural selection as a process driven by chance necessity, devoid of purpose or intent.