How to Report Statistics in Medicine PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download How to Report Statistics in Medicine PDF full book. Access full book title How to Report Statistics in Medicine by Thomas Allen Lang. Download full books in PDF and EPUB format.
Author: Thomas Allen Lang
Publisher: ACP Press
ISBN: 1930513690
Category : Medical
Languages : en
Pages : 512
Get Book Here
Book Description
This volume presents a comprehensive and comprehensible set of guidelines for reporting the statistical analyses and research designs and activities commonly used in biomedical research.
Author: Thomas Allen Lang
Publisher: ACP Press
ISBN: 1930513690
Category : Medical
Languages : en
Pages : 512
Get Book Here
Book Description
This volume presents a comprehensive and comprehensible set of guidelines for reporting the statistical analyses and research designs and activities commonly used in biomedical research.
Author: Xiao-Hua Zhou
Publisher: John Wiley & Sons
ISBN: 1118626044
Category : Medical
Languages : en
Pages : 597
Get Book Here
Book Description
Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.
Author: Michael Harris
Publisher: CRC Press
ISBN: 1135322503
Category : Medical
Languages : en
Pages : 127
Get Book Here
Book Description
It is not necessary to know how to do a statistical analysis to critically appraise a paper. However, it is necessary to have a grasp of the basics, of whether the right test has been used and how to interpret the resulting figures. Short, readable, and useful, this book provides the essential, basic information without becoming bogged down in the
Author: Janet L. Peacock
Publisher: Oxford University Press
ISBN: 0192526731
Category : Medical
Languages : en
Pages : 307
Get Book Here
Book Description
As many medical and healthcare researchers have a love-hate relationship with statistics, the second edition of this practical reference book may make all the difference. Using practical examples, mainly from the authors' own research, the book explains how to make sense of statistics, turn statistical computer output into coherent information, and help decide which pieces of information to report and how to present them. The book takes you through all the stages of the research process, from the initial research proposal, through ethical approval and data analysis, to reporting on and publishing the findings. Helpful tips and information boxes, offer clear guidance throughout, including easily followed instructions on how to: -develop a quantitative research proposal for ethical/institutional approval or research funding -write up the statistical aspects of a paper for publication -choose and perform simple and more advanced statistical analyses -describe the statistical methods and present the results of an analysis. This new edition covers a wider range of statistical programs - SAS, STATA, R, and SPSS, and shows the commands needed to obtain the analyses and how to present it, whichever program you are using. Each specific example is annotated to indicate other scenarios that can be analysed using the same methods, allowing you to easily transpose the knowledge gained from the book to your own research. The principles of good presentation are also covered in detail, from translating relevant results into suitable extracts, through to randomised controlled trials, and how to present a meta-analysis. An added ingredient is the inclusion of code and datasets for all analyses shown in the book on our website (http://medical-statistics.info). Written by three experienced biostatisticians based in the UK and US, this is a step-by-step guide that will be invaluable to researchers and postgraduate students in medicine, those working in the professions allied to medicine, and statisticians in consultancy roles.
Author: Robert H. Riffenburgh
Publisher: Academic Press
ISBN:
Category : Business & Economics
Languages : en
Pages : 680
Get Book Here
Book Description
Medicine deals with treatments that work often but not always, so treatment success must be based on probability. Statistical methods lift medical research from the anecdotal to measured levels of probability. This book presents the common statistical methods used in 90% of medical research, along with the underlying basics, in two parts: a textbook section for use by students in health care training programs, e.g., medical schools or residency training, and a reference section for use by practicing clinicians in reading medical literature and performing their own research. The book does not require a significant level of mathematical knowledge and couches the methods in multiple examples drawn from clinical medicine, giving it applicable context. Easy-to-follow format incorporates medical examples, step-by-step methods, and check yourself exercises Two-part design features course material and a professional reference section Chapter summaries provide a review of formulas, method algorithms, and check lists Companion site links to statistical databases that can be downloaded and used to perform the exercises from the book and practice statistical methods New in this Edition: New chapters on: multifactor tests on means of continuous data, equivalence testing, and advanced methods New topics include: trial randomization, treatment ethics in medical research, imputation of missing data, and making evidence-based medical decisions Updated database coverage and additional exercises Expanded coverage of numbers needed to treat and to benefit, and regression analysis including stepwise regression and Cox regression Thorough discussion on required sample size
Author: Martin Bland
Publisher: Oxford University Press
ISBN: 0192518399
Category : Medical
Languages : en
Pages : 737
Get Book Here
Book Description
Now in its Fourth Edition, An Introduction to Medical Statistics continues to be a 'must-have' textbook for anyone who needs a clear logical guide to the subject. Written in an easy-to-understand style and packed with real life examples, the text clearly explains the statistical principles used in the medical literature. Taking readers through the common statistical methods seen in published research and guidelines, the text focuses on how to interpret and analyse statistics for clinical practice. Using extracts from real studies, the author illustrates how data can be employed correctly and incorrectly in medical research helping readers to evaluate the statistics they encounter and appropriately implement findings in clinical practice. End of chapter exercises, case studies and multiple choice questions help readers to apply their learning and develop their own interpretative skills. This thoroughly revised edition includes new chapters on meta-analysis, missing data, and survival analysis.
Author: James Penston
Publisher:
ISBN: 9781907313332
Category : Mathematics
Languages : en
Pages : 318
Get Book Here
Book Description
About Stats.con - How we've been fooled by statistics-based research in medicine: Statistics-based research is the method by which the causes of disease and the effectiveness of new treatments are investigated. Epidemiological studies and large-scale randomised controlled trials dominate medical research. Judged by the number of papers published each year, this type of research would appear to be a success. Yet it s a triumph of appearance over substance. We ve been cajoled into believing that great advances in medicine have occurred when, in fact, this isn t the case. Large RCTs are placed at the summit of the hierarchy of evidence and are claimed to be the most reliable means of establishing causal relationships in medical research. They are highly complex structures designed to identify small differences in outcome between the active treatment group and controls. But how do we know that the observed difference is caused by the drug? Proponents of RCTs assert that the method excludes alternative explanations namely, the unequal distribution of other causal factors, bias in the assessment of the outcome and chance. In other words, they believe that these studies have internal validity. The primary thesis of stats.con is that the grounds for causal inference in statistics-based research are lacking. Firstly, the components of the RCT including randomisation, allocation concealment, double-blind administration of treatment, the handling of withdrawals and drop-outs, and the statistical tests don t guarantee that the conditions for internal validity have been satisfied. Secondly, the frequentist approach to statistics, which continues to be used in almost all medical research studies despite being subjected to serious criticisms in recent years, is unsound. Thirdly, and most importantly, the inference from a small difference in outcome to the presence of a causal relationship is highly questionable. Given these arguments, it s of some importance to note that neither the results of individual RCTs nor the statistical method in general can be tested independently. This is an inevitable consequence of the subject matter of this type of research which involves heterogeneous samples with unknown mixtures of constituents. The inability to test the results of statistics-based research is of particular concern as fraud is more common than hitherto supposed in medical research. But even if we were to accept the validity of causal inference in this situation and to dismiss concerns about independent testing, we would still face the unpalatable truth that the product of statistics-based research is of little value. The reliability of any generalisation from the results of an individual study to the wider population of patients that is, the external validity is always open to question. We can never know whether the results of a RCT apply to either a particular patient or to a specified group. This is an enormous disadvantage in medicine. But that s not all. The size of the treatment effect in large-scale studies is very small. Indeed, it s so small that the true size of the effect is deliberately hidden by researchers and others with a vested interest in the outcome of the studies. When we look closely, the product of these studies is of dubious worth and doubtful meaning. The reasons for the widespread acceptance of statistics-based research are to be found in the events of the past fifty years or more. History shows how the advocates have used every means at their disposal to spread a flawed methodology and how their views have infiltrated the thinking of generations of researchers, practicing physicians and others involved in the care of patients. But this doesn t apply only to medical research. Many other academic disciplines use similar methods. If, as is argued in stats.con, the case against statistics-based research is made, then the implications extend far beyond the field of medicine.
Author: M. Harris
Publisher: Scion Publishing Ltd
ISBN: 1907904093
Category : Medical
Languages : en
Pages : 128
Get Book Here
Book Description
This new edition of Medical Statistics Made Easy 2nd edition enables readers to understand the key statistical techniques used throughout the medical literature. Featuring a comprehensive updating of the 'Statistics at work' section, this new edition retains a consistent, concise, and user-friendly format. Each technique is graded for ease of use and frequency of appearance in the mainstream medical journals. Medical Statistics Made Easy 2nd edition is essential reading for anyone looking to understand: * confidence intervals and probability values * numbers needed to treat * t tests and other parametric tests * survival analysis If you need to understand the medical literature, then you need to read this book. Reviews: "This book helps medical students understand the basic concepts of medical statistics starting in a 'step-by-step approach'. The authors have designed the book assuming that the reader has no prior knowledge. It focuses on the most common statistical concepts that are likely to be faced in medical literature. All chapters are concise and simple to understand. Each chapter starts with an introduction which consists of “how important” that particular statistical concept is, using a 'star' system. A 'thumbs-up' system shows how easy the statistical concept is to understand. Both these systems indicate time-efficient learning allowing yourself to focus on areas you find most difficult. Following this, there are worked out examples with exam-tips at the end of some chapters. The last chapter, 'Statistics at Work', shows how medical statistics is put into practice using worked out examples from renowned journals. This helps in assessing the reader’s own knowledge and gives them confidence in analysis of statistics of a journal. In conclusion, we would recommend this book as an introduction into medical statistics before plunging into the deep 'statistical' waters! It gives confidence to the reader in taking up the challenge of understanding statistics and [being] able to apply knowledge in analysing medical literature." Stefanie Zhao Lin Lip & Louise Murchison, Scottish Medical Journal, June 2010 "If ever there was a book that completely lived up to its title, this is it...Perhaps above everything, it is the chapter layout and design that makes this book stand out head and shoulders above the crowd. At the beginning of each chapter two questions are posed – how important is the subject in question and how difficult is it to understand? The first is answered on the basis of how often the subject is mentioned / used in papers published in mainstream medical journals. A star rating is then given from one to five with five stars implying use in the majority of papers published. The second question is answered by means of a ‘thumbs up’ grading system. The more thumbs, the easier the concept is to understand (maximum of five). This, of course, provides a route into statistics for even the most idle of uneducated individuals! Five stars and five thumbs must surely indicate time-efficient learning! At the end of each chapter exam tips (light bulb icon!) are given – I doubt anyone could ask for more! The whole way in which the authors have written this book is commendable; the chapters are succinct, easy to follow and a pleasure to read...Is it value for money? – a definite yes even at twice the price. Of course I never exaggerate but if you breathe, you should own this book!" Ian Pearce, Urology News, June 2010
Author: National Research Council
Publisher: National Academies Press
ISBN: 030918651X
Category : Medical
Languages : en
Pages : 163
Get Book Here
Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309465370
Category : Social Science
Languages : en
Pages : 195
Get Book Here
Book Description
The environment for obtaining information and providing statistical data for policy makers and the public has changed significantly in the past decade, raising questions about the fundamental survey paradigm that underlies federal statistics. New data sources provide opportunities to develop a new paradigm that can improve timeliness, geographic or subpopulation detail, and statistical efficiency. It also has the potential to reduce the costs of producing federal statistics. The panel's first report described federal statistical agencies' current paradigm, which relies heavily on sample surveys for producing national statistics, and challenges agencies are facing; the legal frameworks and mechanisms for protecting the privacy and confidentiality of statistical data and for providing researchers access to data, and challenges to those frameworks and mechanisms; and statistical agencies access to alternative sources of data. The panel recommended a new approach for federal statistical programs that would combine diverse data sources from government and private sector sources and the creation of a new entity that would provide the foundational elements needed for this new approach, including legal authority to access data and protect privacy. This second of the panel's two reports builds on the analysis, conclusions, and recommendations in the first one. This report assesses alternative methods for implementing a new approach that would combine diverse data sources from government and private sector sources, including describing statistical models for combining data from multiple sources; examining statistical and computer science approaches that foster privacy protections; evaluating frameworks for assessing the quality and utility of alternative data sources; and various models for implementing the recommended new entity. Together, the two reports offer ideas and recommendations to help federal statistical agencies examine and evaluate data from alternative sources and then combine them as appropriate to provide the country with more timely, actionable, and useful information for policy makers, businesses, and individuals.
