Author: Michael J. Wheeler
Publisher: Springer Science & Business Media
ISBN: 1592599869
Category : Science
Languages : en
Pages : 259
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Book Description
Expert researchers who have developed and applied significant new assays describe in step-by-step detail a variety of methods for measuring a broad variety of hormones, related peptides, and synthetic steroids in various biological fluids. The hormones measured range from glucocorticoids in biological fluids, urinary steroids, aldosterone in blood, and plasma renin activity, to gut hormones in plasma, melatonin, prolactin, 6-sulfatoxymelatonin, and androgens in blood, saliva, and hair. The emphasis is on noncommercial assays so that investigators can set up novel methods suited to their special needs. Commercial assays are also described for comparative purposes. Tutorials on radioimmunoassay, gas chromatography-mass spectrometry, high-performance liquid chromatography, and PCR techniques help the reader to choose the best method for his or her purpose.
Author: John A.H. Wass
Publisher: Oxford University Press, USA
ISBN: 0199235295
Category : Medical
Languages : en
Pages : 2158
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Book Description
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Author: Michael J. Wheeler
Publisher: Humana
ISBN: 9781493962808
Category : Science
Languages : en
Pages : 0
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Book Description
Hormone measurement is necessary for the diagnosis of a wide range of clinical conditions and is essential for monitoring the effectiveness of treatment. As the number of hormone requests in the clinical field rises exponentially, it has become imperative to create hormone assays accessible to researchers with a varied range of equipment. Hormone Assays in Biological Fluids, Second Edition reviews common techniques used to measure hormones as well as relatively new methods such as tandem mass spectrometry. Additionally, subsequent chapters detail methods for a broad range of hormones; Techniques and principles covered are transferable to a wide range of substances across species. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Hormone Assays in Biological Fluids, Second Edition will serve students, technologists, laboratory scientists, and researchers looking to apply, or attain a greater understanding of, methods for measuring hormones.
Author: Michael Wilkinson
Publisher: Cambridge University Press
ISBN: 1316645193
Category : Medical
Languages : en
Pages : 207
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Book Description
A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Author: Owen M. Wolkowitz
Publisher: American Psychiatric Pub
ISBN: 1585627577
Category : Medical
Languages : en
Pages : 612
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Book Description
The mind-body connection is one of the hottest topics in medicine today, documented by enormous amounts of data regarding hormone effects on the brain and behavior. Yet it is only now -- with the debut of this thought-provoking volume -- that we find an up-to-date, sophisticated reference that focuses on the clinical relevance of behavioral endocrinology and is written for practicing clinicians and researchers. This wide-ranging volume shows how the principles and emerging findings of psychoneuroendocrinology can inform modern clinical practice and lead to new breakthroughs in future science and practice. Here, leading authorities -- internationally respected researchers and practicing clinicians -- review empirical findings in their areas of expertise, highlight the clinical significance of these findings, and provide, wherever appropriate, clinical guidelines for the management of patients. Beginning with a lively history of psychoneuroendocrinology (including its many false starts), this book continues on to discussions of the hypothalamic-pituitary-adrenal axis hormone system, the gonadal hormone system, and the thyroid hormone system from each of the three paths generally used for psychoneuroendocrinological investigation: Alterations in endogenous hormone levels observed in primary psychiatric illness Psychiatric concomitants or sequelae of hormonal dysregulation in primary endocrinologic illness Behavioral effects of exogenously administered hormones or hormone antagonists (both the study of the side effects of hormonal medications and the use of hormones and hormone antagonists as psychotropic medications) An unmatched diversity of topics reveals the full breadth and depth of this volume: diabetes mellitus, corticosteroid effects on mood and cognition, Cushing's syndrome and Addison's disease, oral contraceptives and estrogen replacement therapy, psychiatric illness associated with the menstrual cycle and perimenopause, postpartum behavioral changes, anabolic/androgenic steroid use, and a thorough review of thyroid function in psychiatric disorders. Particularly fascinating are sections on the role of neuropeptides and hypothalamic-releasing factors in psychiatric illness, the use of laboratory tests and imaging procedures in evaluating hormonal function in psychiatric patients, the place of newer "alternative" hormonal medications such as melatonin and DHEA in therapeutics, and a provocative and compelling final chapter on the role stress plays in precipitating illness. Designed for both clinician and researcher-scientist, this richly informative guide will also prove an invaluable addition to graduate courses in neuroscience, neuroendocrinology, the biological basis of behavior, and consultation psychiatry. Neuroscientists/neurologists, endocrinologists, obstetricians/gynecologists, internists, family practitioners, nurses, and interested laypersons round out the wide audience for this remarkable volume.
Author: J Chayen
Publisher: Butterworth-Heinemann
ISBN: 148316540X
Category : Medical
Languages : en
Pages : 439
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Book Description
Cytochemical Bioassays: Techniques and Clinical Applications describes the techniques and clinical applications of cytochemical bioassays, particularly with respect to polypeptide hormones. This book discusses the clinical and research implications of studies that use these techniques. This text is comprised of 14 chapters; the first of which introduces the reader to the origins and general principles of cytochemical bioassays, along with their advantages. This discussion is followed by a chapter that explains what is meant by ""an assay""; for what purpose assays are done; the basic components of an assay method; and the nature of the difference between in vivo and in vitro hormone bioassays, in vitro ligand assays, and enzyme assays. Attention then turns to the techniques of cytochemical bioassays and the cytochemical bioassay procedures for adrenocorticotropic hormones; thyroid-stimulating hormones; the thyroid-stimulating antibody of Graves' disease; thyroid growth stimulating and blocking immunoglobulins; and luteinizing hormones. The next chapters focus on the technique and clinical relevance of a cytochemical bioassay for gastrin-like activity and for measurement of antidiuretic hormones, parathyroid hormones, angiotensin II, natriuretic hormones, and hypothalamic regulating hormones. This book will be of interest to clinicians and practitioners of biology, biochemistry, and endocrinology.
Author: I. Nir
Publisher:
ISBN: 9783709144282
Category :
Languages : en
Pages : 420
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Book Description
Author: A. Giustina
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318063398
Category : Medical
Languages : en
Pages : 216
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Book Description
Vitamin D deficiency is prevalent today not only among the elderly but pervasively throughout all ages of life.This is due, in part, to systemic diseases that affect vitamin D metabolism, to changes in lifestyle, such as insufficient exposure to sunlight, and to increased use of sunscreen. Apart from the obvious effects of vitamin D deficiency on skeletal metabolism, the problem is assuming even greater significance because observational and interventional studies have linked vitamin D deficiency to cardiovascular disease, cancer, and diabetes. This book addresses a variety of important issues that have emerged from this fast-moving area of clinical medicine. The topics include assays of vitamin D and its binding protein, effects on aging and associated complications, primary and secondary states of altered parathyroid hormone secretion, vitamin D in the growing years of children and adolescents, nutritional requirements, and vitamin D as it relates to systemic disorders such as diabetes mellitus. Vitamin D in Clinical Medicine aims to offer new insights, in an evidence-based way, on important issues related to vitamin D. It is written for general practitioners and internists, as well as for endocrinologists, nutritionists, pulmonologists, cardiologists, and oncologists.
Author: Michael B. Ranke
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805594143
Category : Medical
Languages : en
Pages : 548
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Book Description
A multitude of new developments, not only in the rapidly advancing field of molecular genetics and steroid metabolism but in all traditional areas of pediatric endocrinology, have influenced the diagnostic approach in children and adolescents with endocrine disorders, thus warranting this 4th, revised and extended edition of 'Diagnostics of Endocrine Function in Children and Adolescents'. Several chapters have been revised completely and all have been thoroughly updated. In addition, new chapters dealing with the muscle-bone unit and bone metabolism have also been incorporated. The original format of the chapters, which are a combination of in-depth discussion of the diagnostic process, practical conclusions and expert advice based on extensive experience, was maintained. Easy-to-use tables and figures allow for quick reference. Flowcharts of possible diagnostic pathways lead to the most frequent diagnoses. Presenting a broad range of diagnostic approaches, test procedures, and normative data required for establishing diagnoses for a broad spectrum of endocrine disorders, this book is an indispensable reference tool not only for endocrinologists and pediatricians but also for professionals in other specialties seeking evidence-based, rapid diagnostic solutions as the basis of advice and therapy for their patients.
Author: Helen E. Turner
Publisher: Oxford University Press
ISBN: 019251265X
Category : Medical
Languages : en
Pages : 931
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Book Description
Oxford Desk Reference: Endocrinology provides easy access to evidence-based materials for quick consultation but also provides an in-depth expert reference for clinical practice. It covers the process of diagnosis, investigation, and management, as well as information for patients. Internationally-renowned experts have brought together evidence, guidelines and their clinical expertise to put trustworthy support at your fingertips. The vast spectrum of endocrine disorders are clearly laid out in self-contained topics for easy reference. Chapters build bridges between pathogenesis, clinical presentation, differential diagnosis and investigation to aid understanding. Careful consideration is given to establishing a diagnosis including the recognition, investigation and management of the rarer diagnoses. The practical treatment of everyday endocrine disorders and the management of life-long conditions are outlined in clear protocols. Chapters are organised by endocrine glands, disorders and syndromes and there are sections on the involvement of hormones in other specialities including endocrine oncology. The continuity from childhood to adolescent and adult endocrinology as well as the needs of older patients is explored in specific sections. Dedicated chapters cover the important roles endocrine specialist nurses play in patient management, and dietetic advice. The editors have included a wealth of practical resources including: · A speedy reference section, which provides summaries and quick direction · A patient advice and reference section, which supports face-to-face discussion with patients · A medicolegal chapter, which outlines risk and DVLA regulations Oxford Desk Reference: Endocrinology is the ideal companion for consultants, registrars associate specialists and clinical assistants as well as those from other disciplines who share endocrine clinics including endocrine surgeons, oncologists, gynaecologists and paediatricians.
