Highly Integrated Microfluidics Design

Highly Integrated Microfluidics Design PDF Author: Dan E. Angelescu
Publisher: Artech House
ISBN: 159693980X
Category : Technology & Engineering
Languages : en
Pages : 269

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Book Description
The recent development of microfluidics has lead to the concept of lab-on-a-chip, where several functional blocks are combined into a single device that can perform complex manipulations and characterizations on the microscopic fluid sample. However, integration of multiple functionalities on a single device can be complicated. This a cutting-edge resource focuses on the crucial aspects of integration in microfluidic systems. It serves as a one-stop guide to designing microfluidic systems that are highly integrated and scalable. This practical book covers a wide range of critical topics, from fabrication techniques and simulation tools, to actuation and sensing functional blocks and their inter-compatibility. This unique reference outlines the benefits and drawbacks of different approaches to microfluidic integration and provides a number of clear examples of highly integrated microfluidic systems.

Highly Integrated Microfluidics Design

Highly Integrated Microfluidics Design PDF Author: Dan E. Angelescu
Publisher: Artech House
ISBN: 159693980X
Category : Technology & Engineering
Languages : en
Pages : 269

Get Book Here

Book Description
The recent development of microfluidics has lead to the concept of lab-on-a-chip, where several functional blocks are combined into a single device that can perform complex manipulations and characterizations on the microscopic fluid sample. However, integration of multiple functionalities on a single device can be complicated. This a cutting-edge resource focuses on the crucial aspects of integration in microfluidic systems. It serves as a one-stop guide to designing microfluidic systems that are highly integrated and scalable. This practical book covers a wide range of critical topics, from fabrication techniques and simulation tools, to actuation and sensing functional blocks and their inter-compatibility. This unique reference outlines the benefits and drawbacks of different approaches to microfluidic integration and provides a number of clear examples of highly integrated microfluidic systems.

CMOS Integrated Lab-on-a-chip System for Personalized Biomedical Diagnosis

CMOS Integrated Lab-on-a-chip System for Personalized Biomedical Diagnosis PDF Author: Hao Yu
Publisher: John Wiley & Sons
ISBN: 1119218357
Category : Technology & Engineering
Languages : en
Pages : 290

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Book Description
A thorough examination of lab-on-a-chip circuit-level operations to improve system performance A rapidly aging population demands rapid, cost-effective, flexible, personalized diagnostics. Existing systems tend to fall short in one or more capacities, making the development of alternatives a priority. CMOS Integrated Lab-on-a-Chip System for Personalized Biomedical Diagnosis provides insight toward the solution, with a comprehensive, multidisciplinary reference to the next wave of personalized medicine technology. A standard complementary metal oxide semiconductor (CMOS) fabrication technology allows mass-production of large-array, miniaturized CMOS-integrated sensors from multi-modal domains with smart on-chip processing capability. This book provides an in-depth examination of the design and mechanics considerations that make this technology a promising platform for microfluidics, micro-electro-mechanical systems, electronics, and electromagnetics. From CMOS fundamentals to end-user applications, all aspects of CMOS sensors are covered, with frequent diagrams and illustrations that clarify complex structures and processes. Detailed yet concise, and designed to help students and engineers develop smaller, cheaper, smarter lab-on-a-chip systems, this invaluable reference: Provides clarity and insight on the design of lab-on-a-chip personalized biomedical sensors and systems Features concise analyses of the integration of microfluidics and micro-electro-mechanical systems Highlights the use of compressive sensing, super-resolution, and machine learning through the use of smart SoC processing Discusses recent advances in complementary metal oxide semiconductor-integrated lab-on-a-chip systems Includes guidance on DNA sequencing and cell counting applications using dual-mode chemical/optical and energy harvesting sensors The conventional reliance on the microscope, flow cytometry, and DNA sequencing leaves diagnosticians tied to bulky, expensive equipment with a central problem of scale. Lab-on-a-chip technology eliminates these constraints while improving accuracy and flexibility, ushering in a new era of medicine. This book is an essential reference for students, researchers, and engineers working in diagnostic circuitry and microsystems.

Joining Technologies

Joining Technologies PDF Author: Mahadzir Ishak
Publisher: BoD – Books on Demand
ISBN: 9535125966
Category : Technology & Engineering
Languages : en
Pages : 286

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Book Description
Joining and welding are two of the most important processes in manufacturing. These technologies have vastly improved and are now extensively used in numerous industries. This book covers a wide range of topics, from arc welding (GMAW and GTAW), FSW, laser and hybrid welding, and magnetic pulse welding on metal joining to the application of joining technologies for textile products. The analysis of temperature and phase transformation is also incorporated. This book also discusses the issue of dissimilar joint between metal and ceramic, as well as the technology of diffusion bonding.

Robotic Cell Manipulation

Robotic Cell Manipulation PDF Author: Dong Sun
Publisher: Academic Press
ISBN: 0323852602
Category : Technology & Engineering
Languages : en
Pages : 548

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Book Description
Robotic Cell Manipulation introduces up-to-date research to realize this new theme of medical robotics. The book is organized in three levels: operation tools (e.g., optical tweezers, microneedles, dielectrophoresis, electromagnetic devices, and microfluidic chips), manipulation types (e.g., microinjection, transportation, rotation fusion, adhesion, separation, etc.), and potential medical applications (e.g., micro-surgery, biopsy, gene editing, cancer treatment, cell-cell interactions, etc.). The technology involves different fields such as robotics, automation, imaging, microfluidics, mechanics, materials, biology and medical sciences. The book provides systematic knowledge on the subject, covering a wide range of basic concepts, theories, methodology, experiments, case studies and potential medical applications. It will enable readers to promptly conduct a systematic review of research and become an essential reference for many new and experienced researchers entering this unique field. - Introduces the applications of robot-assisted manipulation tools in various cell manipulation tasks - Defines many essential concepts in association with the robotic cell manipulation field, including manipulation strategy and manipulation types - Introduces basic concepts and knowledge on various manipulation devices and tasks - Describes some cutting-edge cell manipulation technologies and case studies

Droplet Microfluidics

Droplet Microfluidics PDF Author: Eric Brouzes
Publisher: MDPI
ISBN: 3036501843
Category : Science
Languages : en
Pages : 114

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Book Description
Droplet microfluidics has dramatically developed in the past decade and has been established as a microfluidic technology that can translate into commercial products. Its rapid development and adoption have relied not only on an efficient stabilizing system (oil and surfactant), but also on a library of modules that can manipulate droplets at a high-throughput. Droplet microfluidics is a vibrant field that keeps evolving, with advances that span technology development and applications. Recent examples include innovative methods to generate droplets, to perform single-cell encapsulation, magnetic extraction, or sorting at an even higher throughput. The trend consists of improving parameters such as robustness, throughput, or ease of use. These developments rely on a firm understanding of the physics and chemistry involved in hydrodynamic flow at a small scale. Finally, droplet microfluidics has played a pivotal role in biological applications, such as single-cell genomics or high-throughput microbial screening, and chemical applications. This Special Issue will showcase all aspects of the exciting field of droplet microfluidics, including, but not limited to, technology development, applications, and open-source systems.

Light Driven Micromachines

Light Driven Micromachines PDF Author: George K. Knopf
Publisher: CRC Press
ISBN: 1351001272
Category : Technology & Engineering
Languages : en
Pages : 334

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Book Description
In Light Driven Micromachines, the fundamental principles and unique characteristics of light driven material structures, simple mechanisms and integrated machines are explored. Very small light driven systems provide a number of interesting features and unique design opportunities because streams of photons deliver energy into the system and provide the control signal used to regulate the response of the micron sized device. Through innovative material design and clever component fabrication, these optically powered tiny machines can be created to perform mechanical work when exposed to varying light intensity, wavelength, phase, and/or polarization. The book begins with the scientific background necessary to understand the nature of light and how light can initiate physical movement by inducing material deformation or altering the surrounding environment to impose micro-forces on the actuating mechanisms. The impact of physical size on the performance of light driven mechanisms and machines is discussed, and the nature of light–material interactions is reviewed. These interactions enable very small objects and mechanical components to be trapped and manipulated by a focused light beam, or produce local temperature gradients that force certain materials to undergo shape transformation. Advanced phase transition gels, polymers, carbon-based films and piezoelectric ceramics that exhibit direct light-to-mechanical energy conversion are examined from the perspective of designing optically driven actuators and mechanical systems. The ability of light to create photothermal effects that drive microfluidic processes and initiate the phase transformation of temperature sensitive shape memory materials are also explored in the book. This compendium seeks to inspire the next generation of scientists and engineers by presenting the fundamental principles of this emerging interdisciplinary technology and exploring how the properties of light can be exploited for microfluidic, microrobotic, biomedical and space applications.

Functional Materials and Electronics

Functional Materials and Electronics PDF Author: Jiabao Yi
Publisher: CRC Press
ISBN: 135168275X
Category : Science
Languages : en
Pages : 334

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Book Description
This informative book focuses on newly developed functional materials and their applications for electronic and spintronic devices. Electronic devices have become a part of our daily modern life, involving mobile phones, data storage, computers, and satellites, and there is relentless growth in microelectronics. This volume covers the topics of oxide materials for electronics devices, new materials, and new properties, especially in newly developed research areas, such as oxide magnetic semiconductors and two-dimensional electron gas. Key features: Emphasizes functional materials for electronic devices, including two-dimensional materials, two-dimensional electron gas, multiferroic materials, memory materials, sensor materials, and spintronic materials. Describes the basics as well as new developments of these functional materials and devices.

Microfluidic Methods for Molecular Biology

Microfluidic Methods for Molecular Biology PDF Author: Chang Lu
Publisher: Springer
ISBN: 3319300199
Category : Medical
Languages : en
Pages : 382

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Book Description
This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology studies using model organisms are reviewed in detail. This is an ideal book for students and researchers in the microfluidics and molecular biology fields as well as engineers working in the biotechnology industry. This book also: Reviews exhaustively the latest techniques for single-cell genetic, epigenetic, metabolomic, and proteomic analysis Illustrates microfluidic approaches for inverse metabolic engineering, as well as analysis of circulating exosomes Broadens readers’ understanding of microfluidics convection-based PCR technology, microfluidic RNA-seq, and microfluidics for robust mobile diagnostics

Microfluidics

Microfluidics PDF Author: Bingcheng Lin
Publisher: Springer
ISBN: 3642230504
Category : Science
Languages : en
Pages : 352

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Book Description
Flow Control Methods and Devices in Micrometer Scale Channels, by Shuichi Shoji and Kentaro Kawai. Micromixing Within Microfluidic Devices, by Lorenzo Capretto, Wei Cheng, Martyn Hill and Xunli Zhang. Basic Technologies for Droplet Microfluidics, by Shaojiang Zeng, Xin Liu, Hua Xie and Bingcheng Lin. Electrorheological Fluid and Its Applications in Microfluidics, by Limu Wang, Xiuqing Gong and Weijia Wen. Biosensors in Microfluidic Chips, by Jongmin Noh, Hee Chan Kim and Taek Dong Chung. A Nanomembrane-Based Nucleic Acid Sensing Platform for Portable Diagnostics, by Satyajyoti Senapati, Sagnik Basuray, Zdenek Slouka, Li-Jing Cheng and Hsueh-Chia Chang. Optical Detection Systems on Microfluidic Chips, by Hongwei Gai, Yongjun Li and Edward S. Yeung. Integrated Microfluidic Systems for DNA Analysis, by Samuel K. Njoroge, Hui-Wen Chen, Małgorzata A. Witek and Steven A. Soper. Integrated Multifunctional Microfluidics for Automated Proteome Analyses, by John K. Osiri, Hamed Shadpour, Małgorzata A. Witek and Steven A. Soper. Cells in Microfluidics, by Chi Zhang and Danny van Noort. Microfluidic Platform for the Study of Caenorhabditis elegans,by Weiwei Shi, Hui Wen, Bingcheng Lin and Jianhua Qin.

Utilizing Microfluidics in the Food Industry

Utilizing Microfluidics in the Food Industry PDF Author: C. Anandharamakrishnan
Publisher: Elsevier
ISBN: 0443134545
Category : Technology & Engineering
Languages : en
Pages : 424

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Book Description
"Microfluidics for the food industry thoroughly covers the state-of-the-art applications of microfluidic system for food sector. The book presents fundamental concepts of microfluidic devices, liquid conduction in microfluidics, fabrication techniques, computational approaches, scalability approaches and emerging concepts in nanofluidics. The second section provides details on microfluidics for food structure (emulsion, foams, micro and nano carriers) formulation and aspects for food processing food safety and quality analysis. The last section is dedicated to providing a futuristic view of this rapidly advancing field, emphasizing the need for research and market potential. A comprehensive reference written by world renowned scientists providing both fundamentals and principles or other application sectors in the Microfluidics on food processing. - Addresses the basic fundamental concepts and principles behind the design and fabrication of microfluidic devices - Provides practical guidance on how to analyze and test microfluidic devices - Discusses the application of microfluidic technology for food processing and food safety analysis - Covers major challenges and provides a futuristic overview of microfluidic applications for the food industry - Brings applications, literature reviews, recent developments, methods, and case studies