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Author: Jacopo Lamanna
Publisher: Frontiers Media SA
ISBN: 2832536379
Category : Science
Languages : en
Pages : 117
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Book Description
Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.
Author: Jacopo Lamanna
Publisher: Frontiers Media SA
ISBN: 2832536379
Category : Science
Languages : en
Pages : 117
Get Book Here
Book Description
Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.
Author: Ford Lumban Gaol
Publisher: CRC Press
ISBN: 0429817134
Category : Business & Economics
Languages : en
Pages : 363
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Book Description
Inclusive Development of Society contains papers that were originally presented at the 2018 International Congress on Management and Technology in Knowledge, Service, Tourism & Hospitality (SERVE 2018), held 6-7 October and 15-16 December 2018 in Kuta, Bali, Indonesia and 18-19 October, 2018 at The Southern Federal University, Rostov-on-don, Russia. The contributions deal with various interdisciplinary research topics, particularly in the fields of social sciences, economics and the arts. The papers focus especially on such topics as language, cultural studies, economics, behavior studies, political sciences, media and communication, psychology and human development. The theoretical research studies included here should provide a solid foundation for the development of new tools that explore the possibilities of developing tourism, hospitality, service industries in Knowledge Economic Era, and the empirical papers will advance our knowledge regarding the impact of information technologies in organizations’ and institutions’ practices. These proceedings should be of interest to academics and professionals in the wider field of social sciences, including disciplines such as education, psychology, tourism and knowledge management.
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Department of the Interior and Related Agencies
Publisher:
ISBN:
Category : United States
Languages : en
Pages : 1956
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Book Description
Author: National Institutes of Health (U.S.). Division of Resources Analysis
Publisher:
ISBN:
Category : Federal aid to higher education
Languages : en
Pages : 104
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Book Description
Author: T. G. K. Bryce
Publisher:
ISBN:
Category : Education
Languages : en
Pages : 1046
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Book Description
'Scottish Education' is a frank and authoritative commentary on every aspect of education in Scotland. It provides detailed information on pre-school, primary, secondary and tertiary education.
Author:
Publisher:
ISBN:
Category : Delegated legislation
Languages : en
Pages : 708
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Book Description
Author: Sheldon Krimsky
Publisher: Harvard University Press
ISBN: 0674071093
Category : Science
Languages : en
Pages : 314
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Book Description
Can genes determine which fifty-year-old will succumb to Alzheimer’s, which citizen will turn out on voting day, and which child will be marked for a life of crime? Yes, according to the Internet, a few scientific studies, and some in the biotechnology industry who should know better. Sheldon Krimsky and Jeremy Gruber gather a team of genetic experts to argue that treating genes as the holy grail of our physical being is a patently unscientific endeavor. Genetic Explanations urges us to replace our faith in genetic determinism with scientific knowledge about how DNA actually contributes to human development. The concept of the gene has been steadily revised since Watson and Crick discovered the structure of the DNA molecule in 1953. No longer viewed by scientists as the cell’s fixed set of master molecules, genes and DNA are seen as a dynamic script that is ad-libbed at each stage of development. Rather than an autonomous predictor of disease, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning. Emphasizing relatively new understandings of genetic plasticity and epigenetic inheritance, the authors put into a broad developmental context the role genes are known to play in disease, behavior, evolution, and cognition. Rather than dismissing genetic reductionism out of hand, Krimsky and Gruber ask why it persists despite opposing scientific evidence, how it influences attitudes about human behavior, and how it figures in the politics of research funding.
Author: Shashank Arora
Publisher: Butterworth-Heinemann
ISBN: 0128181273
Category : Technology & Engineering
Languages : en
Pages : 264
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Book Description
Heavy-Duty Electric Vehicles: From Concept to Reality presents a step-by-step design and development guide for heavy-duty electric vehicles. It also offers practical insights based on the commercial application of an electric city bus. Heavy-duty electric vehicle design is challenging due to a lack of clear understanding of the government policies, R&D directions and uncertainty around the performance of various subsystems in an electric powertrain. Therefore, this book discusses key technical aspects of motors, power electronics, batteries and vehicle control systems, and outlines the system integration strategies necessary for design and safe operation of electric vehicles in practice. This comprehensive book serves as a guide to engineers and decision makers involved in electric vehicle development programs and assists them in finding the suitable electric powertrain solution for a given heavy-duty vehicle application. - Offers an overview of various standards and regulations that guide the electric vehicle design process and a comprehensive discussion on various government policies and incentive schemes propelling the growth of heavy electric vehicle markets across the world - Provides a comparative evaluation of different electric drivetrain concepts and a step-by-step power calculation guide for heavy-duty electric powertrain - Explains material selection and manufacturing methods for next generation batteries - Discusses key elements and design rules for creating a robust high voltage energy storage system, appropriate packaging and its support systems including charging network - Includes a concise description of torque mapping, power management and fault handling strategies for inverter drive and control systems - Features case studies to better understand complex topics like charging system requirements and vehicle control system diagnostics
Author: United States. Congress. Senate. Committee on Labor and Public Welfare. Subcommittee on Education
Publisher:
ISBN:
Category : Federal aid to higher education
Languages : en
Pages : 1204
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Book Description
Author: John I'Anson
Publisher: Taylor & Francis
ISBN: 1351654756
Category : Religion
Languages : en
Pages : 190
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Book Description
This book is concerned with re-imagining Religious Education (RE) as this is practiced in schools, colleges and universities throughout the UK and in a wide variety of international educational contexts. On the basis of a critical analysis of current theory and practice in RE the authors argue that this educational framing is no longer plausible in the light of new theoretical developments within the academy. A new educational approach to RE is outlined that challenges students to think and practice differently. This includes a ‘becoming ethnographer’ that can acknowledge socio-material relations and engage the broader literacies necessary for such study. Part One examines how RE has been constructed as a discipline in historical and spatial terms that abstract its study from material concerns. In Part Two, the authors offer some new starting points: Spinoza, Foucault and feminist theory that differently foreground context and relationality, and 'Islam' read as a discursive, located tradition rather than as 'world view'. Finally, Part Three proposes a new trajectory for research and practice in RE, with the aim of re-engaging schools, colleges and universities in a dialogue that promotes thinking and practice that – as educational – is continually in touch with the need to be critical, open-ended and ethically justifiable.
