Handbook of Oxidative Stress in Cancer: Therapeutic Aspects PDF Download
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Author: Sajal Chakraborti
Publisher: Springer Nature
ISBN: 9811654220
Category : Medical
Languages : en
Pages : 4078
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Book Description
This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy.
Author: Sajal Chakraborti
Publisher: Springer Nature
ISBN: 9811654220
Category : Medical
Languages : en
Pages : 4078
Get Book Here
Book Description
This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy.
Author: Sajal Chakraborti
Publisher: Springer
ISBN: 9789811594106
Category : Medical
Languages : en
Pages : 2675
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Book Description
This comprehensive, up-to-date reference work compiles the scientific research on the relationship between various forms of cancer and reactive oxygen species (ROS). It is well known that ROS play a key role in the various steps leading to malignancy, this includes increase in DNA mutation rates. The book brings together exciting reviews, written by leading experts all over the world. The book is divided into four broad sections. Each section describes the role of oxidative stress and underlying mechanisms and pathways, at various stages of cancer, including its role in carcinogenesis, cancer progression and metastasis. Further, the book describes how the reactive oxygen species (ROS) modulate gene expression and signal transduction pathways in cancer. The book discusses the ways to interfere with the cancer progression, and design of anti-cancer drugs. The book provides an integrated approach for better understanding of the development phases of oxidative stress-induced cancers, and mainly the current perspectives about mechanistic aspects of cancer initiation, progression and metastasis. It is a highly resourceful book and would be extremely important to clinicians, students and researchers in the field of cancer genetics, therapeutics and oncology.
Author: Sajal Chakraborti
Publisher:
ISBN: 9789811545016
Category : Oxidative stress
Languages : en
Pages :
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Book Description
Author: Lester Packer
Publisher: CRC Press
ISBN: 0203904044
Category : Medical
Languages : en
Pages : 732
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Book Description
Contains new and expanded material on antioxidants in beverages and herbal products, nitric oxide and selenium, and the effect of vitamin C on cardiovascular disease and of lipoic acid on aging, hyperglycemia, and insulin resistance! Offering over 4200 contemporary references-2000 more than the previous edition-the Second Edition of the Handbook of Antioxidants is an up-to-the-minute source for nutritionists and dietitians, cell biologists and biochemists, cardiologists, oncologists, dermatologists, and medical students in these disciplines.
Author: Adolfo M. Reyes
Publisher: Nova Science Publishers
ISBN: 9781619421783
Category : Oxidative stress
Languages : en
Pages : 0
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Book Description
This book presents new research in the study of oxidative stress. Topics discussed include pharmacological treatments in myocardial ischemia-reperfusion injury; oxidative stress in neurodenegerative disorders, hyptertension, and the cardiovascular system; the role of antioxidant supplementation in ischemic stroke; mitochondria at the crossroads of cancer and oxidative stress; and the influence of aerobic exercise training on post-prandial oxidative stress.
Author: Adolfo M. Reyes
Publisher: Nova Science Publishers
ISBN: 9781619422063
Category : Oxidative stress
Languages : en
Pages : 524
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Book Description
This book presents new research in the study of oxidative stress. Topics discussed include pharmacological treatments in myocardial ischemia-reperfusion injury; oxidative stress in neurodenegerative disorders, hyptertension, and the cardiovascular system; the role of antioxidant supplementation in ischemic stroke; mitochondria at the crossroads of cancer and oxidative stress; and the influence of aerobic exercise training on postprandial oxidative stress.
Author: Victor R Preedy
Publisher: Academic Press
ISBN: 0124055249
Category : Medical
Languages : en
Pages : 325
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Book Description
Cancer: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in cancer and then the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component of this. Oncologists, cancer researchers, and nutritionists are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While oncologists and cancer researchers may study the underlying pathogenesis of cancer, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of oncology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of cancer. Nutritionists can apply information related to mitochondrial oxidative stress in one disease to diet-related strategies in another unrelated disease Dietitians can prescribe new foods or diets containing anti-oxidants for conditions resistant to conventional pharmacological treatments Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams Nutritionists and dietitians will gain an understanding of cell signaling, and be able to suggest new preventative or therapeutic strategies with anti-oxidant rich foods
Author: Ah-Ng Tony Kong
Publisher: CRC Press
ISBN: 1466503718
Category : Medical
Languages : en
Pages : 631
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Book Description
Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and
Author: Victor R Preedy
Publisher: Academic Press
ISBN: 0128195630
Category : Medical
Languages : en
Pages : 592
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Book Description
Cancer: Oxidative Stress and Dietary Antioxidants, Second Edition, covers the science of oxidative stress in cancer and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor-mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component. Other sections cover new organ site tumors—skin and liver cancer, the role of polymorphisms, cytochrome p450s, COX gene, fatty acids, apoptosis, T cells and mitochondria, prevention/protection with anthocyanins, esculetin, nanoparticles, and more. This book is a valuable resource for cancer researchers, oncologists, nutritionists and other members of the biomedical field who are interested in enhancing treatment outcome, improving the quality of life of patients, and developing new treatments in the fight against cancer. Encompasses updated, revised and state-of-the-art information to advance cancer research Bridges the gaps between nutrition, oxidative stress, and cancer, presenting a holistic approach for health care and research Contains wide applicability to cancer research, from prevention to novel therapeutics
Author: Donald Armstrong
Publisher: John Wiley & Sons
ISBN: 1118832485
Category : Science
Languages : en
Pages : 610
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Book Description
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.
