Guidelines for Clinical Trials in Helicobacter Pylori Infection PDF Download
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Author: A. T. R. Axon
Publisher:
ISBN:
Category : Helicobacter pylori
Languages : en
Pages : 23
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Book Description
Author: A. T. R. Axon
Publisher:
ISBN:
Category : Helicobacter pylori
Languages : en
Pages : 23
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Book Description
Author: Francis Mégraud
Publisher:
ISBN:
Category : Helicobacter pylori
Languages : en
Pages : 23
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Book Description
Author: Mikael Sörberg
Publisher:
ISBN: 9789162825843
Category :
Languages : en
Pages : 50
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Book Description
Author: Shigeru Kamiya
Publisher: Springer Nature
ISBN: 303021916X
Category : Medical
Languages : en
Pages : 284
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Book Description
This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.
Author: C. Scarpignato
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805576587
Category : Medical
Languages : en
Pages : 481
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Book Description
Author: Giovanni Gasbarrini
Publisher: Springer
ISBN: 9783642782336
Category : Medical
Languages : en
Pages : 0
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Book Description
A century ago the Italian pathologist Bizzozero described the relationships between spiral bacteria and the mammalian gastro intestinal tract. Since 1982, when Helicobacter pylori was discovered, gastroduodenal disease have been completely revised as a con sequence of the results of basic and clinical research in this field. Progress in understanding the pathogenesis of this bacterium has been made by studying H. pylori infection in animal models. More specific diagnostic tools have been developed using new molecular biology techniques. Future trends are directed towards preparing a specific H. pylori vaccine. A new classification for gastritis, the Sydney System, including H. pylori gastritis, was proposed in 1990. As concerns the clinical approach to peptic ulcer disease in the 1990's, the majority of authors agree on the importance of H. pylori eradication. Moreover, recent clinical studies suggest that H. pylori infection can be associated with other gastroduodenal diseases, such as non ulcer dyspepsia and gastric cancer. Multicenter trials to standardize serological methods and evaluate the efficacy of new antimicrobial therapy schedules are planned throughout different European countries. The fourth Workshop of the European Helicobacter Pylori Study Group was held in Bologna, Italy, in November 1991. Two years before Bologna University celebrated its ninth centennial, giving evidence of being the oldest University in the modern world. Thus the H. pylori story that has continued for more than a century has been discussed once again at the University with the oldest tradition in the world.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 46
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Book Description
The purpose of this document is to suggests points for consideration when designing clinical trials dealing with eradication of H. pylori in gastrointestinal (GI) diseases and to outline elements to be reviewed. The document specifically addresses issues related to clinical trial design for the demonstration of eradication of H. pylori in patients with duodenal ulcers. It sets out minimum requirements related to study design & objectives, diagnosis & definition of H. pylori status, data analysis, studies carried out for other H. pylori-associated GI diseases, and other issues such as drug doses & bioequivalence, length of treatment, and drug interactions.
Author: Huaxiang Xia
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Chi-Jen Lee
Publisher: CRC Press
ISBN: 1420039148
Category : Medical
Languages : en
Pages : 520
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Book Description
The pharmaceutical industry is on the verge of an exciting and challenging century. Advances in pharmaceutical sciences have dramatically changed the processes of discovery and development of new therapeutic drugs and, in turn, resulted in an extraordinary increase in the potential prophylactic and therapeutic interventions. In this atmosphere, an
Author: R.H. Hunt
Publisher: Springer
ISBN: 9789401072991
Category : Medical
Languages : en
Pages : 420
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Book Description
The impact of Helicobacter pylori on basic science and the clinical management of patients with the complications of this infection is bewildering. The explosion of new information both in the laboratory and at the bedside has progressed at an unprecedented rate. Our main objective in furthering this progress has been to integrate this new information and organize a series of top-quality presentations and discussions between investigators and clinicians on all aspects of H. pylori research and to review the current position and future research directions. To that end, the second meeting 'Helicobacter pylori: Basic Mechanisms to Clinical Cure' was organized in June 1996 in Ottawa, Canada, following the successful format of the first such meeting held in Amelia Island, Florida, in 1993. The meeting again focused on all timely aspects of H. pylori research. Internationally renowned basic and clinical scientists, all experts in their respective fields, explored in depth the spectrum of H. pylori infection and the related complications of gastritis, peptic ulcer, gastric cancer and lymphoma.
