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Author: Jim Litster
Publisher: Springer Science & Business Media
ISBN: 9401705461
Category : Science
Languages : en
Pages : 258
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Book Description
This book had its origins in a meeting between two (relatively) young particle technology researchers on Rehobeth Beach in Delaware in 1992 near the holiday house of Reg Davies (then Director of the Particle Science and Technology Research Center in Dupont). As we played in the sand, we shared an excitement for developments in particle technology, especially particle characterization, that would lead operations such as granulation to be placed on a sound scientific and engineering footing. The immediate outcome from this interaction was the development of new industry short courses in granulation and related topics which we taught together both in Australia and North America. This book follows closely the structure and approaches developed in these courses, particularly the emphasis on particle design in granulation, where the impact of both formulation properties and process variables on product attributes needs to be understood and quantified. The book has been a long time in the making. We have been actively preparing the book for at least five years. Although the chapters have relatively good bibliographies, this book is not a review of the field. Rather it is an attempt by the authors to present a comprehensive engineering approach to granulator design, scale up and operation. It is exciting for us to see the explosion of research interest around the world in this area in the last five to seven years. Some of the most recent work will have to find its way into the second edition.
Author: Jim Litster
Publisher: Springer Science & Business Media
ISBN: 9401705461
Category : Science
Languages : en
Pages : 258
Get Book Here
Book Description
This book had its origins in a meeting between two (relatively) young particle technology researchers on Rehobeth Beach in Delaware in 1992 near the holiday house of Reg Davies (then Director of the Particle Science and Technology Research Center in Dupont). As we played in the sand, we shared an excitement for developments in particle technology, especially particle characterization, that would lead operations such as granulation to be placed on a sound scientific and engineering footing. The immediate outcome from this interaction was the development of new industry short courses in granulation and related topics which we taught together both in Australia and North America. This book follows closely the structure and approaches developed in these courses, particularly the emphasis on particle design in granulation, where the impact of both formulation properties and process variables on product attributes needs to be understood and quantified. The book has been a long time in the making. We have been actively preparing the book for at least five years. Although the chapters have relatively good bibliographies, this book is not a review of the field. Rather it is an attempt by the authors to present a comprehensive engineering approach to granulator design, scale up and operation. It is exciting for us to see the explosion of research interest around the world in this area in the last five to seven years. Some of the most recent work will have to find its way into the second edition.
Author: Ajit S. Narang
Publisher: Academic Press
ISBN: 0323481035
Category : Medical
Languages : en
Pages : 894
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Book Description
Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation. - Discusses fundamentals of theory and current industrial practice in the field of wet granulation, including product and process design and role of material properties in wet granulation - Examines the modern evolution of wet granulation through current topics such as established and novel process analytical technologies (PATs), and product development and scale-up paradigms - Written for scientists working within the pharmaceutical industry, as well as academics, regulatory officials and equipment vendors who provide PAT tools and granulation equipment
Author: Dilip M. Parikh
Publisher: CRC Press
ISBN: 1000366383
Category : Medical
Languages : en
Pages : 905
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Book Description
Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies
Author: Gerhard Nestler
Publisher: Brynmorgen Press
ISBN: 9781929565368
Category : Art, Etruscan
Languages : en
Pages : 100
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Book Description
Author: Agba D. Salman
Publisher: Elsevier
ISBN: 0080467881
Category : Science
Languages : en
Pages : 1403
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Book Description
Granulation provides a complete and comprehensive introduction on the state-of-the-art of granulation and how it can be applied both in an academic context and from an industrial perspective. Coupling science and engineering practices it covers differing length scales from the sub-granule level through behaviour through single granules, to bulk granule behaviour and equipment design. With special focus on a wide range of industrially relevant areas from fertilizer production, through to pharmaceuticals. Experimental data is complemented by mathematical modelling in this emerging field, allowing for a greater understanding of the basis of particle products and this important industry sector.Four themes run through the book: 1. The Macro Scale processing for Granulation – including up to date descriptions of the methods used for granulation and how they come about and how to monitor – on-line these changes.2. The Applications of granulation from an industrial perspective, with current descriptive roles and how they are undertaken with relevance to industry, and effective properties.3. Mechanistic descriptions of granulation and the different rate processes occurring within the granulator. This includes methods of modelling the process using Population – Balance Equations, and Multi-level Computational Fluid Dynamics Models.4. The Micro Scale: Granules and Smaller, looking at single granules and there interactions and modelling, while also considering the structure of granules and their constituent liquid bridges.* Covers a wide range of subjects and industrial applications* Provides an understanding of current issues for industrial and academic environments* Allows the reader an understanding of the science behind engineered granulation processes
Author: P. J. Cullen
Publisher: John Wiley & Sons
ISBN: 1118682807
Category : Technology & Engineering
Languages : en
Pages : 508
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Book Description
Written in four parts, this book provides a dedicated and in-depth reference for blending within the pharmaceutical manufacturing industry. It links the science of blending with regulatory requirements associated with pharmaceutical manufacture. The contributors are a combination of leading academic and industrial experts, who provide an informed and industrially relevant perspective of the topic. This is an essential book for the pharmaceutical manufacturing industry, and related academic researchers in pharmaceutical science and chemical and mechanical engineering.
Author: Dilip M. Parikh
Publisher: CRC Press
ISBN: 1616310030
Category : Medical
Languages : en
Pages : 678
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Book Description
The Third Edition presents all pharmaceutical industry personnel and those in academia with critical updates on the recent advances in granulation technology and changes in FDA regulatory guidelines. Addressing precisely how these recent innovations and revisions affect unit operation of particle generation and granulation, this text assists the re
Author: Yihong Qiu
Publisher: Academic Press
ISBN: 008093272X
Category : Medical
Languages : en
Pages : 976
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Book Description
Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: - Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms - Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies - New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development - The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards - It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter - A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies
Author: Luis M. Rubio-Martinez
Publisher: John Wiley & Sons
ISBN: 111919007X
Category : Medical
Languages : de
Pages : 896
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Book Description
Complications in Equine Surgery ist das erste Referenzwerk, das sich ausschließlich damit befasst, verfahrensbezogene und postoperative Komplikationen bei chirurgischen Eingriffen an Pferden zu verstehen, zu vermeiden, zu erkennen und zu managen sowie Prognosen zu formulieren. Die beiden Herausgeber sind anerkannte Fachexperten auf dem Gebiet und präsentieren in ihrer Publikation evidenzbasierte Informationen, klar, zugänglich und nach Körpersystem strukturiert. Das Fachbuch enthält farbige Abbildungen und deckt das gastronintestinale, respiratorische, Muskel-Skelett-, Urogenital- und neurologische System im Detail ab. Jedes Kapitel beginnt mit einer kurzen Einführung des jeweiligen Verfahrens und erläutert, wann und wie das Verfahren einzusetzen ist. Durchgängig wird erläutert, wie man technische Komplikationen erkennt und vermeidet und wie das Management postoperativer Komplikationen aussieht. Inhalt: - Das erste Referenzwerk, das sich insbesondere mit Komplikationen bei chirurgischen Eingriffen an Pferden beschäftigt. - Übersichtliches Format, geordnet nach Körpersystem. - Einheitliche Kapitelstruktur und Benutzerfreundlichkeit. - Präsentiert klinisch relevante Informationen für den Umgang mit verfahrensbezogenen und postoperativen Komplikationen. - Enthält mehr als 350 farbige Abbildungen zur Verdeutlichung der Konzepte. Complications in Equine Surgery richtet sich an Veterinärmediziner und spezialisierte Fachtierärzte. Das Referenzwerk ist unabdingbar, wenn es darum geht, Morbidität und Mortalität bei Pferden zu senken und chirurgische Eingriffe erfolgreicher durchzuführen.
Author: UN Industrial Development Organization
Publisher: Springer Science & Business Media
ISBN: 9780792350323
Category : Nature
Languages : en
Pages : 636
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Book Description
The Fertilizer Manual, 3rd Edition, is a new, fully updated, comprehensive reference on the technology of fertilizer production. The manual contains engineering flow diagrams and process requirements for all major fertilizer processes including ammonia, urea, phosphates, potassium products and many others. Environmental considerations are addressed clearly. Equally important, the manual includes chapters on fertilizer use, production and distribution economics, raw materials, and the status of the fertilizer industry with demand-supply projections. Professionals involved with any phase of fertilizer production, use, marketing, or distribution will find this book valuable.
