Author: Sovereignty Education and Defense Ministry (SEDM)
Publisher: Sovereignty Education and Defense Ministry (SEDM)
ISBN:
Category : Law
Languages : en
Pages : 46
Book Description
Describes the burden of proof imposed upon the government whenever enforcement actions are employed.
Government Burden of Proof, Form #05.025
Author: Sovereignty Education and Defense Ministry (SEDM)
Publisher: Sovereignty Education and Defense Ministry (SEDM)
ISBN:
Category : Law
Languages : en
Pages : 46
Book Description
Describes the burden of proof imposed upon the government whenever enforcement actions are employed.
Publisher: Sovereignty Education and Defense Ministry (SEDM)
ISBN:
Category : Law
Languages : en
Pages : 46
Book Description
Describes the burden of proof imposed upon the government whenever enforcement actions are employed.
SEDM Resource Index, Form #01.008
Author: Sovereignty Education and Defense Ministry (SEDM)
Publisher: Sovereignty Education and Defense Ministry (SEDM)
ISBN:
Category : Law
Languages : en
Pages : 65
Book Description
Master index of all Forms, Litigation Tools, Response Letters, and Exhibits grouped by resource type and then Item Number. Does not include Member Subscription Library content.
Publisher: Sovereignty Education and Defense Ministry (SEDM)
ISBN:
Category : Law
Languages : en
Pages : 65
Book Description
Master index of all Forms, Litigation Tools, Response Letters, and Exhibits grouped by resource type and then Item Number. Does not include Member Subscription Library content.
National Criminal Justice Thesaurus
Author:
Publisher:
ISBN:
Category : Subject headings
Languages : en
Pages : 516
Book Description
Publisher:
ISBN:
Category : Subject headings
Languages : en
Pages : 516
Book Description
Looseleaf Regulations System
Author: United States. Internal Revenue Service
Publisher:
ISBN:
Category : Income tax
Languages : en
Pages : 12
Book Description
The IRS Looseleaf regulation system is a compilation of all tax regulations issued by the Service, except those relating to alcohol, tobacco, firearms and tax conventions.
Publisher:
ISBN:
Category : Income tax
Languages : en
Pages : 12
Book Description
The IRS Looseleaf regulation system is a compilation of all tax regulations issued by the Service, except those relating to alcohol, tobacco, firearms and tax conventions.
Therapeutic Modulation of the Complement System: Clinical Indications and Emerging Drug Leads
Author: John D. Lambris
Publisher: Frontiers Media SA
ISBN: 2889634701
Category :
Languages : en
Pages : 185
Book Description
The complement system is a multi-tasking gatekeeper of innate immunity thatintricately interacts with other key defense systems, such as the endothelial barrier,contact activation and coagulation systems, in maintaining tissue immunosurveillanceand homeostasis. Its rapid and forceful activation in the bloodstream not onlyensures the effective containment of microbial infections through potent cytolyticmechanisms, but also alerts the adaptive immune compartment to ensure the mountingof a proper humoral immune response against foreign antigens. However, there isa lurking ‘dark side’ that can lead complement astray, fueling a self-perpetuatingvicious cycle of inflammation, exuberant immune activation and irreversible tissueinjury that collectively exacerbate both acute and chronic pathologies. Indeed,complement dysregulation or excessive activation have been widely recognized askey pathogenic drivers in a wide spectrum of inflammatory or immune-mediateddiseases. Targeted modulation of the complement system at various points ofthe cascade has revealed promising therapeutic targets for ameliorating diseasescores in a number of conditions ranging from ocular, neurodegenerative andthromboinflammatory disorders, to cancer, periodontal diseases, chronic hemolyticanemias, ischemia-reperfusion organ injury, antibody-mediated transplant rejectionand hemodialysis-triggered inflammation. Elegant pre-clinical studies employing a diversified toolbox of highly specificcomplement inhibitors in rodent or primate models of disease have opened newavenues of therapeutic exploration by providing proof of concept for the therapeuticefficacy of complement modulation. At the same time, the clinical experience gainedduring this last decade with the sole complement-specific drug currently in the clinic,eculizumab, has rekindled the interest of biopharmaceutical companies in developingnew and potent complement therapeutics for complement-driven diseases. In this respect, the complement field is witnessing a new surge of clinical trialsthat are evaluating the safety, PK/PD profile and clinical efficacy of promising drugcandidates in a number of clinical conditions driven by complement imbalance orover-activation.
Publisher: Frontiers Media SA
ISBN: 2889634701
Category :
Languages : en
Pages : 185
Book Description
The complement system is a multi-tasking gatekeeper of innate immunity thatintricately interacts with other key defense systems, such as the endothelial barrier,contact activation and coagulation systems, in maintaining tissue immunosurveillanceand homeostasis. Its rapid and forceful activation in the bloodstream not onlyensures the effective containment of microbial infections through potent cytolyticmechanisms, but also alerts the adaptive immune compartment to ensure the mountingof a proper humoral immune response against foreign antigens. However, there isa lurking ‘dark side’ that can lead complement astray, fueling a self-perpetuatingvicious cycle of inflammation, exuberant immune activation and irreversible tissueinjury that collectively exacerbate both acute and chronic pathologies. Indeed,complement dysregulation or excessive activation have been widely recognized askey pathogenic drivers in a wide spectrum of inflammatory or immune-mediateddiseases. Targeted modulation of the complement system at various points ofthe cascade has revealed promising therapeutic targets for ameliorating diseasescores in a number of conditions ranging from ocular, neurodegenerative andthromboinflammatory disorders, to cancer, periodontal diseases, chronic hemolyticanemias, ischemia-reperfusion organ injury, antibody-mediated transplant rejectionand hemodialysis-triggered inflammation. Elegant pre-clinical studies employing a diversified toolbox of highly specificcomplement inhibitors in rodent or primate models of disease have opened newavenues of therapeutic exploration by providing proof of concept for the therapeuticefficacy of complement modulation. At the same time, the clinical experience gainedduring this last decade with the sole complement-specific drug currently in the clinic,eculizumab, has rekindled the interest of biopharmaceutical companies in developingnew and potent complement therapeutics for complement-driven diseases. In this respect, the complement field is witnessing a new surge of clinical trialsthat are evaluating the safety, PK/PD profile and clinical efficacy of promising drugcandidates in a number of clinical conditions driven by complement imbalance orover-activation.
Psychology and Pathophysiological Outcomes of Eating
Author: Akikazu Takada
Publisher:
ISBN: 9781839687785
Category :
Languages : en
Pages : 0
Book Description
The psychology of eating is regulated by neural mechanisms. When not well controlled, eating may result in disorders and health hazards such as obesity, type 2 diabetes mellitus, and vascular diseases. Lifestyles and cultures influence eating habits, thus there are differences in the prevalence of health problems depending upon living environments. This book examines the psychology and the pathophysiological outcomes of eating. Chapters address such topics as the influence of lifestyle, circadian rhythm, sleep, and fragrant odors on appetite and weight regulation; the impact of glucose, sucrose, lactate, and ketone bodies on the brain; the consequences of glycation stress on the skeletal muscle; and much more.
Publisher:
ISBN: 9781839687785
Category :
Languages : en
Pages : 0
Book Description
The psychology of eating is regulated by neural mechanisms. When not well controlled, eating may result in disorders and health hazards such as obesity, type 2 diabetes mellitus, and vascular diseases. Lifestyles and cultures influence eating habits, thus there are differences in the prevalence of health problems depending upon living environments. This book examines the psychology and the pathophysiological outcomes of eating. Chapters address such topics as the influence of lifestyle, circadian rhythm, sleep, and fragrant odors on appetite and weight regulation; the impact of glucose, sucrose, lactate, and ketone bodies on the brain; the consequences of glycation stress on the skeletal muscle; and much more.
Code of Federal Regulations
Author:
Publisher:
ISBN:
Category : Administrative law
Languages : en
Pages : 1088
Book Description
Special edition of the Federal register. Subject/agency index for rules codified in the Code of Federal Regulations, revised as of Jan. 1 ...
Publisher:
ISBN:
Category : Administrative law
Languages : en
Pages : 1088
Book Description
Special edition of the Federal register. Subject/agency index for rules codified in the Code of Federal Regulations, revised as of Jan. 1 ...
Artificial Intelligence and Sustainable Computing
Author: Hari Mohan Dubey
Publisher: Springer Nature
ISBN: 981161220X
Category : Technology & Engineering
Languages : en
Pages : 483
Book Description
This book presents the outcome of two-day 2nd International e-Conference on Sustainable and Innovative Solutions for Current Challenges in Engineering and Technology (ICSISCET 2020) held at Madhav Institute of Technology & Science (MITS), Gwalior, India, from December 18–19, 2020. The book extensively covers recent research in artificial intelligence (AI) that knit together nature-inspired algorithms, evolutionary computing, fuzzy systems, computational intelligence, machine learning, deep learning, etc., which is very useful while dealing with real problems due to their model-free structure, learning ability, and flexible approach. These techniques mimic human thinking and decision-making abilities to produce systems that are intelligent, efficient, cost-effective, and fast. The book provides a friendly and informative treatment of the topics which makes this book an ideal reference for both beginners and experienced researchers.
Publisher: Springer Nature
ISBN: 981161220X
Category : Technology & Engineering
Languages : en
Pages : 483
Book Description
This book presents the outcome of two-day 2nd International e-Conference on Sustainable and Innovative Solutions for Current Challenges in Engineering and Technology (ICSISCET 2020) held at Madhav Institute of Technology & Science (MITS), Gwalior, India, from December 18–19, 2020. The book extensively covers recent research in artificial intelligence (AI) that knit together nature-inspired algorithms, evolutionary computing, fuzzy systems, computational intelligence, machine learning, deep learning, etc., which is very useful while dealing with real problems due to their model-free structure, learning ability, and flexible approach. These techniques mimic human thinking and decision-making abilities to produce systems that are intelligent, efficient, cost-effective, and fast. The book provides a friendly and informative treatment of the topics which makes this book an ideal reference for both beginners and experienced researchers.
India's Neighbourhood
Author: Vishal Chandra
Publisher:
ISBN: 9788182747067
Category : Armies
Languages : en
Pages : 0
Book Description
Examines the role, relevance and status of armies in the dynamic socio-political milieu of the countries in India's South Asian neighbourhood. This book is part of an ongoing endeavour to further explore and understand the role of the Army in shaping the political destiny and defining the ideational evolution of states in South Asia.
Publisher:
ISBN: 9788182747067
Category : Armies
Languages : en
Pages : 0
Book Description
Examines the role, relevance and status of armies in the dynamic socio-political milieu of the countries in India's South Asian neighbourhood. This book is part of an ongoing endeavour to further explore and understand the role of the Army in shaping the political destiny and defining the ideational evolution of states in South Asia.
Poetic Inquiry
Author:
Publisher: BRILL
ISBN: 9087909519
Category : Education
Languages : en
Pages : 404
Book Description
Poetic Inquiry: Vibrant Voices in the Social Sciences, co-edited by Monica Prendergast, Carl Leggo and Pauline Sameshima, features many of the foremost scholars working worldwide in aesthetic ways through poetry.
Publisher: BRILL
ISBN: 9087909519
Category : Education
Languages : en
Pages : 404
Book Description
Poetic Inquiry: Vibrant Voices in the Social Sciences, co-edited by Monica Prendergast, Carl Leggo and Pauline Sameshima, features many of the foremost scholars working worldwide in aesthetic ways through poetry.