Genomics of Bacterial Metal Resistance PDF Download
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Author: Alessio Mengoni
Publisher: MDPI
ISBN: 3036503900
Category : Science
Languages : en
Pages : 238
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Book Description
The importance of understanding metal–microbe interactions underlies a number of social–economic issues in the world. The antimicrobial resistance era has created a need for novel antimicrobials and within this fieldm metal and metalloid ions are promising solutions. Pollution sites, either co-contaminated with metals or with metals as the sole pollutant, contain microbes that are present as key participants, with both of these issues habing links to agriculture. Microbes also play key roles in the global geochemical cycle of many elements. Such statements solidify the need to understand metal–microbe interactions. Given that genomics has arguably become the most useful tool in biology, the application of this technology within the field of understanding metal resistance comes as no surprise. Whilst by no means comprehensive, this book provides examples of the applications of genomic approaches in the study of metal–microbe interactions. Here, we present a collection of manuscripts that highlights some present directions in the field. The book starts with a collection of three papers evaluating aspects of the genomics of the archetype metal resistant bacteria, Cuprividus metallidurans. This is followed by four studies that evaluate the mechanisms of metal resistance. The next two papers assess metal resistance in agricultural related situations, including a review on metal resistance in Listeria. The book concludes with a review on metal phytoremediation via Rhizobia and two subsequent studies of metal biotechnology relevance.
Author: Alessio Mengoni
Publisher: MDPI
ISBN: 3036503900
Category : Science
Languages : en
Pages : 238
Get Book Here
Book Description
The importance of understanding metal–microbe interactions underlies a number of social–economic issues in the world. The antimicrobial resistance era has created a need for novel antimicrobials and within this fieldm metal and metalloid ions are promising solutions. Pollution sites, either co-contaminated with metals or with metals as the sole pollutant, contain microbes that are present as key participants, with both of these issues habing links to agriculture. Microbes also play key roles in the global geochemical cycle of many elements. Such statements solidify the need to understand metal–microbe interactions. Given that genomics has arguably become the most useful tool in biology, the application of this technology within the field of understanding metal resistance comes as no surprise. Whilst by no means comprehensive, this book provides examples of the applications of genomic approaches in the study of metal–microbe interactions. Here, we present a collection of manuscripts that highlights some present directions in the field. The book starts with a collection of three papers evaluating aspects of the genomics of the archetype metal resistant bacteria, Cuprividus metallidurans. This is followed by four studies that evaluate the mechanisms of metal resistance. The next two papers assess metal resistance in agricultural related situations, including a review on metal resistance in Listeria. The book concludes with a review on metal phytoremediation via Rhizobia and two subsequent studies of metal biotechnology relevance.
Author: Wolfgang Banzhaf
Publisher: Springer Nature
ISBN: 3030398315
Category : Computers
Languages : en
Pages : 600
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Book Description
This edited research monograph brings together contributions from computer scientists, biologists, and engineers who are engaged with the study of evolution and how it may be applied to solve real-world problems. It also serves as a Festschrift dedicated to Erik D. Goodman, the founding director of the BEACON Center for the Study of Evolution in Action, a pioneering NSF Science and Technology Center headquartered at Michigan State University. The contributing authors are leading experts associated with the center, and they serve in top research and industrial establishments across the US and worldwide. Part I summarizes the history of the BEACON Center, with refreshingly personal chapters that describe Erik's working and leadership style, and others that discuss the development and successes of the center in the context of research funding, projects, and careers. The chapters in Part II deal with the evolution of genomes and evolvability. The contributions in Part III discuss the evolution of behavior and intelligence. Those in Part IV concentrate on the evolution of communities and collective dynamics. The chapters in Part V discuss selected evolutionary computing applications in domains such as arts and science, automated program repair, cybersecurity, mechatronics, and genomic prediction. Part VI deals with evolution in the classroom, using creativity in research, and responsible conduct in research training. The book concludes with a special chapter from Erik Goodman, a short biography that concentrates on his personal positive influences and experiences throughout his long career in academia and industry.
Author: Simon Silver
Publisher: Springer Science & Business Media
ISBN: 1461559936
Category : Science
Languages : en
Pages : 479
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Book Description
This is the first volume on the role of metal ions in regulating genes to focus not only on toxicity effects of metals but also on the role of metal ions in normal metabolisms, in both prokaryotes and in eukaryotes. This book is a comprehensive treatment of the role of metal ions in gene regulation, and it will be of great utility for those doing basic biological and biomedical research.
Author: Frans J. de Bruijn
Publisher: John Wiley & Sons
ISBN: 1119004896
Category : Science
Languages : en
Pages : 1472
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Book Description
Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.
Author: Dietrich H. Nies
Publisher: Springer Science & Business Media
ISBN: 3540697713
Category : Science
Languages : en
Pages : 455
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Book Description
This book covers allocation of metals in cells, metal transporter, storage and metalloregulatory proteins, cellular responses to metal ion stress, transcription of genes involved in metal ion homeostasis, uptake of essential metals, metal efflux and other detoxification mechanisms. The book also discusses metal bioreporters for the nanomolar range of concentration and tools to address the metallome. In addition, coverage details specific metals.
Author: Javid A. Parray
Publisher: John Wiley & Sons
ISBN: 1119547954
Category : Science
Languages : en
Pages : 372
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Book Description
SOIL BIOREMEDIATION A practical guide to the environmentally sustainable bioremediation of soil Soil Bioremediation: An Approach Towards Sustainable Technology provides the first comprehensive discussion of sustainable and effective techniques for soil bioremediation involving microbes. Presenting established and updated research on emerging trends in bioremediation, this book provides contributions from both experimental and numerical researchers who provide reports on significant field trials. Soil Bioremediation instructs the reader on several different environmentally friendly bioremediation techniques, including: Bio-sorption Bio-augmentation Bio-stimulation Emphasizing molecular approaches and biosynthetic pathways of microbes, this one-of-a-kind reference focuses heavily on the role of microbes in the degradation and removal of xenobiotic substances from the environment and presents a unique management and conservation perspective in the field of environmental microbiology. Soil Bioremediation is perfect for undergraduate students in the fields of environmental science, microbiology, limnology, freshwater ecology and microbial biotechnology. It is also invaluable for researchers and scientists working in the areas of environmental science, environmental microbiology, and waste management.
Author: P.S. Lovett
Publisher: Springer Science & Business Media
ISBN: 0585323860
Category : Science
Languages : en
Pages : 226
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Book Description
Reviews recent research in eukaryotic, agricultural, environmental, and microbial biotechnology with a view to keeping scientists, government officials, and industrialists up to date on trends and advances in subspecialties adjacent to their own. Some of the specific topics are moveable elements in the human genome, agricultural applications of coat protein mediated protection, and the analysis of epitope in the cholera family of enterotoxins. The 29 papers were presented at a conference in Bangkok, Thailand, August 1990. Annotation copyright by Book News, Inc., Portland, OR
Author: Francisco Rodriguez-Valera
Publisher: Springer
ISBN:
Category : Science
Languages : en
Pages : 162
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Book Description
Author: Boyan B. Bonev
Publisher: John Wiley & Sons
ISBN: 111994077X
Category : Science
Languages : en
Pages : 288
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Book Description
AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Author: Stuart B. Levy
Publisher: Springer Science & Business Media
ISBN: 1468439839
Category : Medical
Languages : en
Pages : 692
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Book Description
This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. This was the first meeting of its kind in the Southern Hemisphere. The meeting place was selected for its relaxed and comfortable climate, conducive to interactions among participants. More importantly the locale facilitated the participation of nearby Latin American clinical and research scientists who deal directly with the health manifestations of pathogenic p1asmids. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there. The book includes the talks as well as extended abstracts of poster presentations from the meeting. This combination, which provides readers with reviews as well as recent findings, captures the full scientific exchange which took place during the 5-day meeting. As one indication of pathogenicity related to p1asmids, the conferees were surveyed for gastro-intestina1 problems during and after their stay in the Dominican Republic. The results are summarized at the end of this book.
