Genomic Surveillance and Pandemic Preparedness

Genomic Surveillance and Pandemic Preparedness PDF Author: Rajesh Pandey
Publisher: Elsevier
ISBN: 0443187681
Category : Science
Languages : en
Pages : 428

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Book Description
Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference—moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness. Highlights different aspects of genomic surveillance, from theory to implementation to inferences Covers a broad range of infectious diseases, with emphasis on recent COVID-19 studies Shares methods and approaches for sequencing-based pathogen detection, diagnostics, and surveillance Facilitates international collaboration in drug and vaccine development

Genomic Surveillance and Pandemic Preparedness

Genomic Surveillance and Pandemic Preparedness PDF Author: Rajesh Pandey
Publisher: Elsevier
ISBN: 0443187681
Category : Science
Languages : en
Pages : 428

Get Book

Book Description
Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference—moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness. Highlights different aspects of genomic surveillance, from theory to implementation to inferences Covers a broad range of infectious diseases, with emphasis on recent COVID-19 studies Shares methods and approaches for sequencing-based pathogen detection, diagnostics, and surveillance Facilitates international collaboration in drug and vaccine development

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022–2032

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022–2032 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240084770
Category : Medical
Languages : en
Pages : 58

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Book Description


Considerations for developing a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential

Considerations for developing a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240076565
Category : Medical
Languages : en
Pages : 28

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Book Description
Policy considerations to strengthen genomic surveillance for pathogens with pandemic and epidemic potential is a support tool that provides key consideration and a proposed stepwise approach for countries to develop a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential. This document is intended for use by all stakeholders at the national and subnational level relevant to the development and implementation of the strategy or action plan, including health authorities, One Health partners, donors, public health officers, academia, the private sector and laboratory specialists.

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential, 2022-2032

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential, 2022-2032 PDF Author:
Publisher: World Health Organization
ISBN: 9240046976
Category : Medical
Languages : en
Pages : 32

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Book Description
The Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022-2032 provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, and its implementation should reinforce end-to-end capacities including sample collection, diagnostics, data sharing and analysis. The strategy aims to facilitate the connectivity between different disease control programs and surveillance networks. This interoperability will strengthen the cross-cutting essential public health laboratory functions underpinning genomics holistically. The strategy articulates the overarching goal, objectives and strategic actions needed. These are dependent on commitments from countries, partners and WHO for their implementation.

Future surveillance for epidemic and pandemic diseases

Future surveillance for epidemic and pandemic diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240080953
Category : Medical
Languages : en
Pages : 59

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Book Description
Surveillance is a pillar of the public health response to epidemics and pandemics. Yet, gaps in surveillance, from the local to the global, continue to leave the world vulnerable to infectious hazards. To address these vulnerabilities, the health emergency preparedness, response, and resilience (HEPR) architecture calls for a new approach to future surveillance - collaborative surveillance - that aligns traditional tactics with new initiatives to safeguard health for all. This report reflects the input and advice on future surveillance of leading experts with different skills, worldviews and experiences who share a commitment to better prepare for future infectious hazards. It charts a course towards future surveillance and collaborative action.

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022-2032

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022-2032 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240057404
Category : Medical
Languages : en
Pages : 26

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Book Description
The Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022-2032 provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, and its implementation should reinforce end-to-end capacities including sample collection, diagnostics, data sharing and analysis. The strategy aims to facilitate the connectivity between different disease control programs and surveillance networks. This interoperability will strengthen the cross-cutting essential public health laboratory functions underpinning genomics holistically. The strategy articulates the overarching goal, objectives and strategic actions needed. These are dependent on commitments from countries, partners and WHO for their implementation.

National Strategy for the COVID-19 Response and Pandemic Preparedness

National Strategy for the COVID-19 Response and Pandemic Preparedness PDF Author: Joseph R. Biden, Jr.
Publisher: Simon and Schuster
ISBN: 1510767614
Category : Political Science
Languages : en
Pages : 329

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Book Description
The ultimate guide for anyone wondering how President Joe Biden will respond to the COVID-19 pandemic—all his plans, goals, and executive orders in response to the coronavirus crisis. Shortly after being inaugurated as the 46th President of the United States, Joe Biden and his administration released this 200 page guide detailing his plans to respond to the coronavirus pandemic. The National Strategy for the COVID-19 Response and Pandemic Preparedness breaks down seven crucial goals of President Joe Biden's administration with regards to the coronavirus pandemic: 1. Restore trust with the American people. 2. Mount a safe, effective, and comprehensive vaccination campaign. 3. Mitigate spread through expanding masking, testing, data, treatments, health care workforce, and clear public health standards. 4. Immediately expand emergency relief and exercise the Defense Production Act. 5. Safely reopen schools, businesses, and travel while protecting workers. 6. Protect those most at risk and advance equity, including across racial, ethnic and rural/urban lines. 7. Restore U.S. leadership globally and build better preparedness for future threats. Each of these goals are explained and detailed in the book, with evidence about the current circumstances and how we got here, as well as plans and concrete steps to achieve each goal. Also included is the full text of the many Executive Orders that will be issued by President Biden to achieve each of these goals. The National Strategy for the COVID-19 Response and Pandemic Preparedness is required reading for anyone interested in or concerned about the COVID-19 pandemic and its effects on American society.

National Strategy for Pandemic Influenza

National Strategy for Pandemic Influenza PDF Author: Homeland Security Council (U.S.)
Publisher: International Medical Publishing
ISBN: 9781588088895
Category : Medical
Languages : en
Pages : 0

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Book Description
This Implementation Plan clarifies the roles and responsibilities of governmental and non-governmental entities, including Federal, State, local, and tribal authorities and regional, national, and international stakeholders, and provides preparedness guidance for all segments of society.--Preface.

Spike

Spike PDF Author: Jeremy Farrar
Publisher: Profile Books
ISBN: 1782839100
Category : Medical
Languages : en
Pages : 269

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Book Description
SHORTLISTED FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2022 THE TIMES SCIENCE BOOK OF THE YEAR A GUARDIAN BEST POLITICS BOOK OF THE YEAR A TOP 5 SUNDAY TIMES BESTSELLER *Revised and updated edition with new chapter reflecting on the impact of Covid-19 two years on, and what come next* Did the UK government really 'follow the science' throughout the Covid-19 pandemic, as it claims? As head of the Wellcome Trust, Jeremy Farrar was one of the first people in the world to hear about a mysterious new disease in China - and to learn it could readily spread between people. A member of the SAGE emergency committee, Farrar was a key figure in both the UK and the World Health Organization at the onset of the Covid-19 pandemic amid great uncertainty, fast-moving situations and missed opportunities. Spike is his widely acclaimed inside story. His account casts light on the UK government's claims to be 'following the science' and is informed not just by Farrar's views but by interviews with other top scientists and political figures.

Exploring Lessons Learned from a Century of Outbreaks

Exploring Lessons Learned from a Century of Outbreaks PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309490359
Category : Medical
Languages : en
Pages : 231

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Book Description
In November 2018, an ad hoc planning committee at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics. This publication summarizes the presentations and discussions from both workshops.