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Author: J. Perry Gustafson
Publisher: Springer Science & Business Media
ISBN: 0387241876
Category : Science
Languages : en
Pages : 257
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Book Description
Genome Exploitation: Data Mining the Genome is developed from the 23rd Stadler Genetic Symposium. This volume discusses and illustrates how scientists are going to characterize and make use of the massive amount of information being accumulated about the plant and animal genomes. Genome Exploitation: Data Mining the Genome is a state-of-the-art picture on mining the Genome databases. This is one of the few times that researchers in both plants and animals will be working together to create a seminal data resource.
Author: J. Perry Gustafson
Publisher: Springer Science & Business Media
ISBN: 0387241876
Category : Science
Languages : en
Pages : 257
Get Book Here
Book Description
Genome Exploitation: Data Mining the Genome is developed from the 23rd Stadler Genetic Symposium. This volume discusses and illustrates how scientists are going to characterize and make use of the massive amount of information being accumulated about the plant and animal genomes. Genome Exploitation: Data Mining the Genome is a state-of-the-art picture on mining the Genome databases. This is one of the few times that researchers in both plants and animals will be working together to create a seminal data resource.
Author: Marc Lappé
Publisher: Random House (NY)
ISBN:
Category : Law
Languages : en
Pages : 376
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Book Description
Author: S. Block
Publisher:
ISBN:
Category :
Languages : en
Pages : 21
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Book Description
In 1997, JASON conducted a DOE-sponsored study of the human genome project with special emphasis on the areas of technology, quality assurance and quality control, and informatics. The present study has two aims: first, to update the 1997 Report in light of recent developments in genome sequencing technology, and second, to consider possible roles for the DOE in the "post-genomic" era, following acquisition of the complete human genome sequence.
Author: David B. Resnik
Publisher: State University of New York Press
ISBN: 0791485943
Category : Science
Languages : en
Pages : 251
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Book Description
DNA patenting has emerged as a hot topic in science policy and bioethics as private companies and government agencies spend billions of dollars on genetic research and development in a race to identify, sequence, and analyze DNA from human, animal, and plant species. David B. Resnik's Owning the Genome explores the ethical, social, philosophical, theological, and policy issues surrounding DNA patenting and develops a comprehensive approach to the topic. Resnik considers arguments for and against DNA patenting and concludes that only a patent on a whole human genome would be inherently immoral, while the morality of other DNA patents depends on their consequences for science, medicine, agriculture, industry, and society. He also stresses the importance of government regulations and policies in order to minimize the harmful effects of patenting while promoting the beneficial ones.
Author: J. Perry Gustafson
Publisher: Springer Science & Business Media
ISBN: 1489911367
Category : Science
Languages : en
Pages : 227
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Book Description
The potato (Solanum tuberosum L. ) tuber is a major food source in many countries of the world, and subsequently potato has been the target of a good deal of effort directed at engineering disease and herbicide tolerance, and improvements in various crop characteristics. Consequently investigations into the regulation of gene expression in tubers is relevant to these endeavours, as tubers are the main target organ for modification of gene expression. We have been interested in the regulation of genes in tubers for these reasons. Morphologically tubers are modified stems, which have enlarged radially by limited cell division and substantial expansion. At the molecular level, tuber development is characterised by a massive increase in starch deposition and the synthesis of a limited number of abundant proteins. These include proteinase inhibitors and a 40kd group of proteins called patatin, which are acyl hydrolases. Together these proteins account for over 50% of tuber proteins (reviewed by Bevan, 1991). The synthesis of these proteins has parallels to the synthesis of other somatic storage proteins, especially the VSP proteins of soybean. In both potato and soybean, removal of the sink for these proteins (tubers and pods, respectively) causes deposition in other tissues (Staswick, 1990). It is hypothesised that transcriptional control of the genes encoding these proteins is regulated in part by source-sink relationships of metabolites or other factors. In the case of VSPs, both amino acid levels and jasmonic acid play a major regulatory role (Staswick et aI.
Author: Giuseppe Gasparre
Publisher: Academic Press
ISBN: 0128226420
Category : Science
Languages : en
Pages : 596
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Book Description
The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including cancer, neurodegenerative, age-related, mtDNA depletion, deletion, and point mutation diseases. Nucleosides supplementation, mitoTALENs, and mitoZNF nucleases are among the therapeutic approaches examined in-depth. With increasing funding for mtDNA studies, many clinicians and clinician scientists are turning their attention to mtDNA disease association. This book provides the tools and background knowledge required to perform new, impactful research in this exciting space, from distinguishing a haplogroup-defining variant or disease-related mutation to exploring emerging therapeutic pathways. Fully examines recent advances and technological innovations in the field, enabling new mtDNA studies, variant and mutation identification, pathogenic assessment, and therapies Disease discussion accompanied by diagnostic and therapeutic strategies currently implemented clinically Outlines and discusses essential research protocols and perspectives for young scientists to pick up Features an international team of authoritative contributors from basic biologists to clinician-scientists
Author: Doris Schroeder
Publisher: Springer
ISBN: 3319647318
Category : Philosophy
Languages : en
Pages : 144
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Book Description
This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.
Author: J.P. Gustafson
Publisher: Springer Science & Business Media
ISBN: 0387767231
Category : Medical
Languages : en
Pages : 232
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Book Description
This title develops from the 24th Stadler symposium. It explores the general theme "GENOME EXPLOITATION: Data Mining the Genomes". The idea behind the theme is to discuss and illustrate how scientists are going to characterize and make use of the massive amount of information being accumulated about plant and animal genomes. The book presents a state-of-the-art picture on mining the Genome databases. Its chapters are authored by key stars in the field.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309047986
Category : Medical
Languages : en
Pages : 353
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Book Description
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Author: David B. Resnik
Publisher: SUNY Press
ISBN: 9780791459324
Category : Science
Languages : en
Pages : 254
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Book Description
A clear, introductory overview of the issues surrounding gene patenting.
