Genetics of Complex Human Diseases PDF Download
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Author: Ammar Al-Chalabi
Publisher:
ISBN: 9780879698829
Category : Medical genetics
Languages : en
Pages : 0
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Book Description
Many human diseases – including Alzheimer's disease, schizophrenia, cancer, and cardiovascular disease – have complex genetics that require sophisticated analysis. Genetics of Complex Human Diseases: A Laboratory Manual& brings together the tools that geneticists use to find disease genes with the genetic concepts and statistical theories that underpin these research approaches. Topics covered include basic genetics and Mendelian inheritance, statistical methods, genetic epidemiology, linkage studies, transmission disequilibrium test analysis, variance components analysis, genome-wide association studies, copy-number variation, methods for high-throughput genotyping, the complexity of RNA editing, and genetic computer programs. The book's chapters, written by leading investigators in the field, blend practical information and reviews of each topic, providing both the how and the why of complex disease analysis. Genetics of Complex Human Diseasesis an important guide for anyone with an interest in human genetics or who uses genetic techniques in the study of diseases with complex inheritance.
Author: Ammar Al-Chalabi
Publisher:
ISBN: 9780879698829
Category : Medical genetics
Languages : en
Pages : 0
Get Book Here
Book Description
Many human diseases – including Alzheimer's disease, schizophrenia, cancer, and cardiovascular disease – have complex genetics that require sophisticated analysis. Genetics of Complex Human Diseases: A Laboratory Manual& brings together the tools that geneticists use to find disease genes with the genetic concepts and statistical theories that underpin these research approaches. Topics covered include basic genetics and Mendelian inheritance, statistical methods, genetic epidemiology, linkage studies, transmission disequilibrium test analysis, variance components analysis, genome-wide association studies, copy-number variation, methods for high-throughput genotyping, the complexity of RNA editing, and genetic computer programs. The book's chapters, written by leading investigators in the field, blend practical information and reviews of each topic, providing both the how and the why of complex disease analysis. Genetics of Complex Human Diseasesis an important guide for anyone with an interest in human genetics or who uses genetic techniques in the study of diseases with complex inheritance.
Author: Maitreya J. Dunham
Publisher:
ISBN: 9781621821342
Category : Cytogenetik
Languages : en
Pages : 0
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Book Description
Methods in Yeast Genetics is a course that has been offered annually at Cold Spring Harbor Laboratory for the last 45 years. This is an updated edition of the course manual, which provides a set of teaching experiments, along with protocols and recipes for the standard techniques and reagents used in the study of yeast biology. Since the last edition of the manual was published (2005), revolutionary advances in genomics, proteomics, and imaging technologies have had a significant impact on the field. The 11 experiments included in this manual provide a foundation of methods for any modern-day yeast lab. These methods emphasize combinations of classical and modern genetic approaches, including isolation and characterization of mutants, two-hybrid analysis, tetrad analysis, complementation, and recombination. Also covered are molecular genetic techniques for genome engineering. Additional experiments introduce fundamental techniques in yeast genomics, including both performance and interpretation of Synthetic Genetic Array analysis, multiplexed whole genome and barcode sequencing, and comparative genomic hybridization to DNA arrays. Comparative genomics is introduced using different yeast strains to study natural variation, evolution, and quantitative traits. This manual covers the full repertoire of genetic approaches needed to dissect complex biological problems in the yeast Saccharomyces cerevisiae.
Author: Jeffrey H. Miller
Publisher: CSHL Press
ISBN: 9780879693497
Category : Medical
Languages : en
Pages : 484
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Book Description
University of California, Los Angeles. Introduction to bacterial genetics, including laboratory methods, for advanced students and beginning researchers. Handbook with plastic spiral-bound laboratory manual.
Author: Gregore Koliantz
Publisher:
ISBN: 9780891185611
Category : Electronic books
Languages : en
Pages : 0
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Book Description
Cell Division(Mitosis): Looking at Chromosomes -- Restriction Testing -- Extraction of Genomic DNA -- Polymerase Chain Reaction -- Cloning 1 Generating Recombinant Plasmids -- Cloning 2 Minipreping -- Southern Blotting 1 DNA Transfer -- Southern Blotting 2 DNA-DNA Hybridization and Sequence Detection -- Regulation of Gene Expression -- Physical Properties of DNA and DNA Assay -- Transmission Genetics (Heredity) -- Meiosis and Analysis of Crossing Over -- Complementation Test -- Molecular Markers: Mapping the Genome of Arabidopsis -- Population Genetics How Changes Occur within a Population -- Front Matter.
Author: G. P. Rdei
Publisher: World Scientific
ISBN: 9789810227807
Category : Science
Languages : en
Pages : 1150
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Book Description
"Redei has created an outstanding compendium of genetics. Arranged as a dictionary, the book is almost an encyclopedic collection of terms & concepts ... The author has managed to define terms with appropriate mixtures of depth & detail for the researcher, along with clarity useful for the nonexpert." Choice, 1998
Author: Chiyedza Small
Publisher:
ISBN: 9781524988159
Category :
Languages : en
Pages :
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Book Description
Author: Mark David Rose
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 212
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Book Description
An intensive course in yeast genetics has been held at Cold Spring Harbor Laboratory for some years, and the course manual reflects its content and scope. Since its last publication in 1987, this manual's sequence of experiments has been extensively updated and expanded, and the protocols and append
Author: A. M. Winchester
Publisher: McGraw-Hill Science, Engineering & Mathematics
ISBN:
Category : Medical
Languages : en
Pages : 248
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Book Description
Give your students the opportunity to apply the scientific method to "real" -not simulated- lab investigations in both classical and molecular genetics. It is appropriate for a range of genetics and molecular biology laboratory courses because it incorporates material spanning the areas of basic genetics, molecular genetics, and human genetics. Since the first edition, "Laboratory Manual of Genetics has been carefully constructed to be student-oriented.
Author: William Webb
Publisher: Ridiculously Simple Books
ISBN:
Category : Science
Languages : en
Pages : 46
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Book Description
Discover the fascinating world of genetics in this comprehensive and engaging guide, which delves into the very core of life itself. From the simplest organisms to the complexities of the human body, this book unravels the mysteries of heredity, molecular biology, and evolution, providing readers with a deeper understanding of the intricate workings of life. Written in a friendly and conversational tone, this guide is designed to be accessible to readers of all backgrounds, from curious novices to seasoned enthusiasts. Subtle humor is sprinkled throughout, making the learning experience both enjoyable and informative. Each chapter is meticulously crafted to build upon the previous one, ensuring a coherent and captivating journey through the world of genetics. In this book, you will explore the history of genetic research, from Mendel's groundbreaking work with pea plants to the awe-inspiring advances in biotechnology and genome editing. Along the way, you will encounter the renowned scientists who have shaped our understanding of genetics, and gain insights into the ethical considerations that accompany the ever-evolving field. You will also discover key terms and concepts that will help you navigate the complex world of genetics, as well as additional resources to further your understanding and satisfy your curiosity. This book will inspire you to delve deeper into the subject, spark your imagination, and fuel your passion for genetics. Embark on an extraordinary journey through the microscopic world that lies at the heart of every living organism, and unlock the secrets that govern the blueprint of life. This book will leave you with a newfound appreciation for the incredible science of genetics and the wonders of the natural world.
Author: Benjamin Pierce
Publisher: Macmillan
ISBN: 9780716775492
Category : Science
Languages : en
Pages : 836
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Book Description
Based on the author's more than twenty years of teaching experience, Genetics: A Conceptual Approach offers a fresh new way of introducing the major concepts and mechanics of genetics, focusing students on the big picture without overwhelming them with detail.
