The Genetics and Biology of Sex Determination PDF Download
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Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 9780470843468
Category : Science
Languages : en
Pages : 286
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Book Description
Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 9780470843468
Category : Science
Languages : en
Pages : 286
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Book Description
Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045371
Category : Science
Languages : en
Pages : 524
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Book Description
Do persons exposed to radiation suffer genetic effects that threaten their yet-to-be-born children? Researchers are concluding that the genetic risks of radiation are less than previously thought. This finding is explored in this volume about the children of atomic bomb survivors in Hiroshima and Nagasakiâ€"the population that can provide the greatest insight into this critical issue. Assembled here for the first time are papers representing more than 40 years of research. These documents reveal key results related to radiation's effects on pregnancy termination, sex ratio, congenital defects, and early mortality of children. Edited by two of the principal architects of the studies, J. V. Neel and W. J. Schull, the volume also offers an important comparison with studies of the genetic effects of radiation on mice. The wealth of technical details will be immediately useful to geneticists and other specialists. Policymakers will be interested in the overall conclusions and discussion of future studies.
Author: Maxwell Colin Robertson
Publisher: Austin Macauley Publishers
ISBN: 1035843013
Category : Fiction
Languages : en
Pages : 163
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Book Description
As Earth’s biome crumbles, humanity fails to develop the technologies necessary to stop an impending climate disaster. Faced with widespread starvation and environmental ruin, a radical faction seeks to preserve a segment of humankind by unleashing a deadly virus, targeting the vast heterosexual majority in a drastic attempt to reduce the population and save the planet. However, this extreme measure falls short of halting the escalating environmental catastrophe. With the planet deteriorating rapidly, the remnants of humanity embark on a daring exodus. They set off on a 6,000-year journey to the nearest habitable planet outside our solar system. This epic voyage, devoid of star or warp drive, demands a completely self-sustaining environment, where everything, including the colonists themselves, must be recycled. Amidst this backdrop, one man finds himself an outsider on this formidable journey, constrained by strict rules governing all aspects of life, including reproduction, which is meticulously controlled to preserve the colony’s genetic health. Defying these regulations, he forms a clandestine relationship, leading to the conception of an unauthorized child. This grave breach of protocol poses a moral dilemma for the crew: how should they deal with this infraction, and what consequences will their decision have for the future of their fragile society? This narrative explores the complexities of survival, ethics, and human relationships in the face of a daunting interstellar challenge.
Author: Bryan Sykes
Publisher: W. W. Norton & Company
ISBN: 9780393058963
Category : Science
Languages : en
Pages : 336
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Book Description
Examines the history and future of the Y chromosome and maintains that because it is unable to exchange genetic material or repair itself, the day will come when it will cease to exist.
Author: José Callejas-Fernández
Publisher: Royal Society of Chemistry
ISBN: 1782625216
Category : Science
Languages : en
Pages : 411
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Book Description
Nanoparticles are attractive for many biomedical applications such as imaging, therapeutics and diagnostics. This new book looks at different soft nanoparticles and their current and potential uses in medicine and health including magnetoliposomes, micro/nanogels, polymeric micelles, DNA particles, dendrimers and bicelles. Each chapter provides a description of the synthesis of the particles and focus on the techniques used to characterize the size, shape, surface charge, internal structure, and surface microstructure of the nanoparticles together with modeling and simulation methods. By giving a strong physical-chemical approach to the topic, readers will gain a good background into the subject and an overview of recent developments. The multidisciplinary point of view makes the book suitable for postgraduate students and researchers in physics, chemistry, and biology interested in soft matter and its uses.
Author: Graham Zimmatore
Publisher: Mirrors In The Sky
ISBN: 9781420861792
Category : Fiction
Languages : en
Pages : 494
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Book Description
When Damien Birch a brilliant young geneticist discovers a series of microdots containing binary code in a set of ancient manuscripts written six centuries before Christ he is catapulted into a quest to unravel his own destiny. Buried in the mountains of Tibet an alien craft holds secrets of a radically advanced DNA technology and revelations that expose the genus of the Infinati, a despotic syndicate of eight family dynasties who have been the true architects of war, famine and planetary decay down the ages and still continue their reign of terror today. Assisted by a few trusted friends he embarks on a perilous adventure leading them into the very core of the most clandestine and suppressive regime on earth in a daring plot to undo the hegemony they wield over mankind as a whole. With each discovery comes another twist, another turn in what becomes a desperate struggle to prevent a genetic meltdown of the human race.
Author: Kim Sterelny
Publisher: Icon Books
ISBN:
Category : Science
Languages : en
Pages : 226
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Book Description
Already an international bestseller, this completely revised edition updates the story of science's most bitter argument.
Author: Egbert J.W. Boers
Publisher: Springer Science & Business Media
ISBN: 3540419209
Category : Computers
Languages : en
Pages : 530
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Book Description
This book constitutes the refereed proceedings of five application-oriented workshops held concurrently as EvoWorkshops 2001 in Como, Italy in April 2001. The 52 revised full papers presented were carefully reviewed and selected out of 75 submissions. The papers are organized in topical sections on graph problems, Knapsack problems, ant algorithms, assignment problems, evolutionary algorithms analysis, permutative problems, aeronautics, image analysis and signal processing, evolutionary learning, and evolutionary scheduling and timetabling.
Author: Stephen E. Hughes
Publisher: Trafford Publishing
ISBN: 1553691636
Category : History
Languages : en
Pages : 528
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Book Description
The Iraqi Military and its Weapons of Mass Destruction, Saddam Hussein and Bid Laden alliance.
Author: Martine Demeunynck
Publisher: John Wiley & Sons
ISBN: 3527605665
Category : Science
Languages : en
Pages : 754
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Book Description
The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such as metal complexes, peptides, oligonucleotides and a wide array of synthetic organic compounds, is as manifold as the functions of nucleic acids. Nucleic acid recognition sequences are often found in the major or minor groove of a double strand, while other typical interactions include intercalation between base pairs or the formation of triple or quadruple helices. One example of a binding mode that has recently been proposed is end stacking on such complex structures as the telomere tetraplex. In this comprehensive book, internationally recognized experts describe in detail the important aspects of nucleic acid binding, and in so doing present impressive approaches to drug design. Since typical substances may be created naturally or synthetically, emphasis is placed on natural products, chemical synthesis, the use of combinatorial libraries, and structural characterization. The whole is rounded off by contributions on molecular modeling, as well as investigations into the way in which any given drug interacts with its nucleic acid recognition site.
