Genetic Variation and Human Disease

Genetic Variation and Human Disease PDF Author: Kenneth M. Weiss
Publisher: Cambridge University Press
ISBN: 9780521336604
Category : Medical
Languages : en
Pages : 384

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Book Description
Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.

Genetic Variation and Human Disease

Genetic Variation and Human Disease PDF Author: Kenneth M. Weiss
Publisher: Cambridge University Press
ISBN: 9780521336604
Category : Medical
Languages : en
Pages : 384

Get Book Here

Book Description
Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.

Genetic Variation

Genetic Variation PDF Author: Rafael Trindade Maia
Publisher: BoD – Books on Demand
ISBN: 183881096X
Category : Medical
Languages : en
Pages : 298

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Book Description
Genetic diversity is one of the measures of biodiversity and has consequences in biological variation. It is crucial to understand the evolutionary and adaptative processes in all living species. This book is an interdisciplinary and integrated work that will contribute to the knowledge of academics from different areas of biological sciences. This collection of scientific papers was chosen and analyzed to offer readers a broad and integrated view of the importance of genetic diversity in the evolution and adaptation of living beings, as well as practical applications of the information needed to analyze this diversity in different organisms. This book was edited by geneticist researchers and provides academics with up-to-date and quality information on the subject.

Evaluating Human Genetic Diversity

Evaluating Human Genetic Diversity PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309184746
Category : Science
Languages : en
Pages : 101

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Book Description
This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

Human Variation

Human Variation PDF Author: Aravinda Chakravarti
Publisher:
ISBN: 9781936113255
Category : Science
Languages : en
Pages : 200

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Book Description
"A subject collection from Cold Spring Harbor perspectives in medicine."

Genetic Variation and Its Maintenance

Genetic Variation and Its Maintenance PDF Author: Derek Frank Roberts
Publisher: Cambridge University Press
ISBN: 9780521332576
Category : Science
Languages : en
Pages : 318

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Book Description
This volume considers the genetic variability of human populations, particularly in the tropics: its origins and maintenance, and its contribution to the phenotypic variability of complex characters. The first section deals with the ways of analysing genetic variation and provides a valuable review of relevant developments in molecular biology. The origin and maintenance of genetic diversity is considered in the second section with data presented for Pacific, African, Asian and Central American populations. The final section concerns characters in which the genetic contribution to variability is complex and shows how such characters may be used to elucidate biological problems of affinity and differentiation, of adaptation and survival. Published as part of the Decade of the Tropics research programme of the International Union of Biological Sciences, this volume will be of particular interest to human geneticists, physical and biological anthropologists.

Eco-Evolutionary Dynamics

Eco-Evolutionary Dynamics PDF Author:
Publisher: Academic Press
ISBN: 0128014334
Category : Science
Languages : en
Pages : 392

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Book Description
The theme of this volume is to discuss Eco-evolutionary Dynamics. - Updates and informs the reader on the latest research findings - Written by leading experts in the field - Highlights areas for future investigation

Genetic Variation

Genetic Variation PDF Author: Michael P. Weiner
Publisher: CSHL Press
ISBN: 0879697806
Category : Human genetics
Languages : en
Pages : 472

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Book Description
This is the first compendium of protocols specifically geared towards genetic variation studies. It includes detailed step-by-step experimental protocols that cover the complete spectrum of genetic variation in humans and model organisms, along with advice on study design and analyzing data.

Virus as Populations

Virus as Populations PDF Author: Esteban Domingo
Publisher: Academic Press
ISBN: 0128163321
Category : Science
Languages : en
Pages : 428

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Book Description
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes

Homology Molecular Modeling

Homology Molecular Modeling PDF Author: Rafael Trindade Maia
Publisher: BoD – Books on Demand
ISBN: 1839628057
Category : Science
Languages : en
Pages : 147

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Book Description
Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.

Frontiers in the Nutrition Sciences

Frontiers in the Nutrition Sciences PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309041465
Category : Medical
Languages : en
Pages : 241

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Book Description
This series of individually authored chapters examines the nature and extent of scientific advances in the nutrition sciences and describes both future opportunities in the field and barriers to progress. Despite concern about declining attention to nutrition in universities and medical schools, the authors offer a bright and challenging future in nutrition research and training that should generate enthusiasm among young researchers and teachers for this indispensable component of biology.