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Author: Simone Badal McCreath
Publisher: Elsevier
ISBN: 0443186588
Category : Medical
Languages : en
Pages : 849
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Book Description
Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting. Covers the main sources of natural bioactive substances Contains practice questions and laboratory exercises at the end of every chapter to test learning and retention Describes how pharmacokinetics and pharmacodynamics play a crucial role in discerning the relationships of active metabolites to bioavailability and function at active sites Includes a dedicated chapter on the effect of plant metabolites on SARS-CoV-2
Author: Simone Badal McCreath
Publisher: Elsevier
ISBN: 0443186588
Category : Medical
Languages : en
Pages : 849
Get Book Here
Book Description
Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting. Covers the main sources of natural bioactive substances Contains practice questions and laboratory exercises at the end of every chapter to test learning and retention Describes how pharmacokinetics and pharmacodynamics play a crucial role in discerning the relationships of active metabolites to bioavailability and function at active sites Includes a dedicated chapter on the effect of plant metabolites on SARS-CoV-2
Author: Prof(Dr)Sailesh Narayan
Publisher: Newredmars Education Pvt Ltd
ISBN: 9393620717
Category : Business & Economics
Languages : en
Pages : 235
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Book Description
This textbook marks a pioneering attempt to align with the updated syllabus set by the Pharmacy Council of India for semester-4, focusing on Pharmacognosy & Phytochemistry-I. While numerous established authors have penned texts on Pharmacognosy, this edition distinguishes itself by presenting information in a simplified manner, complemented with abundant tables, figures, and essential diagrams. The primary goal is to facilitate easy comprehension for students. Aligned with the revised syllabus of the Bachelor of Pharmacy (B. Pharm.) course regulations 2014, this book follows the norms outlined in Regulations 6, 7 & 8 and subsequent amendments from 2017 onward, ensuring uniformity across India. The content is structured to match the semester-wise syllabus, with Pharmacognosy & Phytochemistry-I falling under semester-IV. This subject comprises five sub-units: Unit – I: Encompassing discussions on the history, scope, interconnections with related disciplines, and contemporary applications of Pharmacognosy. It delves into crude drug classifications, various sources, and emphasizes quality control techniques, including detection methods for adulterants through microscopic evaluation and camera lucida. Unit − II: This unit provides a comprehensive exploration of cultivation, collection, processing, and storage of naturally derived drugs. It emphasizes Good Agricultural Practice, factors influencing cultivation, and the role of plant hormones. Additionally, it covers crop improvement techniques such as polyploidy, mutation, and hybridization, as well as the conservation of medicinal and aromatic plants. Unit − III: Explores alternative cultivation methods through in-vitro techniques, specifically plant cell and tissue culture. It traces the historical development, types of cultures, nutritional requirements, growth, and maintenance under sterile laboratory conditions. The unit also touches upon applications of plant tissue culture in Pharmacognosy. Unit − IV: Focuses on Pharmacognosy's role in allopathy and traditional medicinal systems like Ayurveda, Unani, Siddha, Homeopathy, and Chinese medicine. It elucidates the significance of plant secondary metabolites and methods for identifying alkaloids, glycosides, flavonoids, tannins, volatile oils, and resins. Unit − V: Covers the study of biological sources, chemical nature, and uses of drugs derived from plant fibers and primary metabolites. Detailed discussions include their chemistry, sources, preparation, evaluation, therapeutic uses, and commercial utility as Pharmaceutical aids. Additionally, it delves into important drugs obtained from marine sources. This book endeavors to offer contemporary knowledge in a systematic manner across all units. Your feedback and constructive criticism are invaluable and will be incorporated into future editions to rectify any shortcomings. SYLLABUS UNIT-I Introduction to Pharmacognosy: (a) Definition, history, scope and development of Pharmacognosy (b) Sources of Drugs – Plants, Animals, Marine & Tissue culture (c) Organized drugs, unorganized drugs (dried latex, dried juices, dried extracts, gums and mucilage’s, oleoresins, and oleo- gum -resins). Classification of drugs: Alphabetical, morphological, taxonomical, chemical, pharmacological, chemo and Sero taxonomical classification of drugs. Quality control of Drugs of Natural Origin: Adulteration of drugs of natural origin. Evaluation by organoleptic, microscopic, physical, chemical and biological methods and properties. Quantitative microscopy of crude drugs including lycopodium spore method, leaf constants, camera lucida and diagrams of microscopic objects to scale with camera lucida. UNIT-II Cultivation, Collection, Processing and storage of drugs of natural origin: Cultivation and Collection of drugs of natural origin Factors influencing cultivation of medicinal plants. Plant hormones and their applications. Polyploidy, mutation and hybridization with reference to medicinal plants. Conservation of medicinal plants. UNIT-III Plant tissue culture: Historical development of plant tissue culture, types of cultures, Nutritional requirements, growth and their maintenance. Applications of plant tissue culture in pharmacognosy. Edible vaccines UNIT IV Pharmacognosy in various systems of medicine: Role of Pharmacognosy in allopathy and traditional systems of medicine namely, Ayurveda, Unani, Siddha, Homeopathy and Chinese systems of medicine. Introduction to secondary metabolites: Definition, classification, properties and test for identification of Alkaloids, Glycosides, Flavonoids, Tannins, Volatile oil and Resins UNIT V Study of biological source, chemical nature and uses of drugs of natural origin containing following drugs. Plant Products: Fibress - Cotton, Jute, Hemp Hallucinogens, Teratogens, Natural allergens Primary metabolites: General introduction, detailed study with respect to chemistry, sources, preparation, evaluation, preservation, storage, therapeutic used and commercial utility as Pharmaceutical Aids and/or Medicines for the following Primary metabolites: Carbohydrates: Acacia, Agar, Tragacanth, Honey Proteins and Enzymes: Gelatine, casein, proteolytic enzymes (Papain, bromelain, serratiopeptidase, urokinase, streptokinase, pepsin). Lipids (Waxes, fats, fixed oils): Castor oil, Chaulmoogra oil, Wool Fat, Bees Wax Marine Drugs: Novel medicinal agents from marine sources.
Author: William Charles Evans
Publisher: Elsevier Health Sciences
ISBN: 9780702041891
Category : Medical
Languages : en
Pages : 3322
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Book Description
This encyclopedic reference work on pharmacognosy covers the study of those natural substances, principally plants, that find a use in medicine. Its popularity and longevity stem from the book's balance between classical (crude and powdered drugs' characterization and examination) and modern (phytochemistry and pharmacology) aspects of this branch of science, as well as the editor's recognition in recent years of the growing importance of complementary medicines, including herbal, homeopathic and aromatherapy. No other book provides such a wealth of detail. A reservoir of knowledge in a field where there is a resurgence of interest - plants as a source of drugs are of growing interest both in complementary medicine fields and in the pharmaceutical industry in their search for new 'lead compounds'. Dr Evans has been associated with the book for over 20 years and is a recognised authority in all parts of the world where pharmacognosy is studied, his knowledge and grasp of the subject matter is unique. Meticulously referenced and kept up to date by the editor, new contributors brought in to cover new areas. New chapter on 'Neuroceuticals'. Addition of many new compounds recently added to British Pharmacopoeia as a result of European harmonisation. Considers development in legal control and standardisation of plant materials previously regarded as 'herbal medicines'. More on the study of safety and efficacy of Chinese and Asian drugs. Quality control issues updated in line with latest guidelines (BP 2007).
Author: Roland Barret
Publisher: Elsevier
ISBN: 0081027605
Category : Technology & Engineering
Languages : en
Pages : 174
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Book Description
Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific concerns of the European Pharmacopeia – the industrialist's bible – its role, and a description of the monographs of active principles. - Defines the lifecycle of drugs - Explains the physico-chemical properties and consequences of a drug - Studies the fundamental concepts of medicinal chemistry - Describes the active ingredient monographs
Author: Gunnar Samuelsson
Publisher: Swedish Pharmaceutical Press
ISBN: 9789198094251
Category : Natural products
Languages : en
Pages : 0
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Book Description
Drugs of Natural Origin is a unique multidisciplinary book suitable for undergraduate and graduate students and teachers in the area of natural product science, but also as a complementary book for disciplines like medicinal chemistry, biochemistry and pharmacology. The book can also serve society as a scientific source for the understanding of a sustainable use of natural products in the development of new drugs, scientifically based herbal remedies, and environmentally friendly biomolecules. During evolution, molecules have been developed for specific functions in nature. These bioactive substances have a potential as new drug candidates in drug development, but also as pharmacological tools, intermediates or templates for synthesis of drugs. This book deals with terrestrial and marine bioactive substances of plant, microbial or animal origin. The occurrence, biosynthesis, isolation, chemistry and medical use are described together with basic research strategies. An increased understanding of the medical importance of bioactive natural products has developed in society. Since the publication of the sixth edition, six years ago, considerable progress has been achieved in the study of biosynthetic pathways, mainly based on gene technology. The revolution in high-throughput sequencing technology has given an increasing access to microbial genome sequences, which opens up new possibilities in the discovery of novel bioactive natural products. This development is reflected in a substantial revision and expansion of the book, but also removal of some sections containing products remotely associated with drugs. The new book also contains description of novel drugs marketed since the publication of the previous edition, especially in the field of diabetes, cancer and infection.
Author: Chukwuebuka Egbuna
Publisher: Academic Press
ISBN: 0128202858
Category : Medical
Languages : en
Pages : 576
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Book Description
Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals, nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals, their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery. This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful. - Includes the history and current highlights in phytomedicine, along with classifications of crude drugs, herbal drug technologies and herbal cosmeticology - Provides detailed information on herbal remedies and toxicity, traditional and alternative systems of medicine, and applications of microbiology and biotechnology in drug discovery - Discusses the nutritional and health benefits of nutraceuticals and how they help in the management and treatment of metabolic diseases
Author: Paul M. Dewick
Publisher: John Wiley & Sons
ISBN: 9780471496410
Category : Law
Languages : en
Pages : 524
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Book Description
This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Author: Gary Walsh
Publisher: John Wiley & Sons
ISBN: 111868575X
Category : Science
Languages : en
Pages : 499
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Book Description
Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309082587
Category : Medical
Languages : en
Pages : 172
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Book Description
This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Author: Dr Biren Shah
Publisher: Elsevier India
ISBN: 8131234584
Category : Medical
Languages : en
Pages : 48
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Book Description
This comprehensive textbook primarily aims at fulfilling the syllabus requirements of B.Pharm. students. It is specifically designed to impart knowledge about the alternative systems of medicine and modern pharmacognosy. Additionally, it will also serve as a valuable information resource to other health sciences students and researchers working in the field of herbal technology.
