From Melanocytes to Melanoma

From Melanocytes to Melanoma PDF Author: Vincent J. Hearing
Publisher: Springer Science & Business Media
ISBN: 159259994X
Category : Medical
Languages : en
Pages : 673

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Book Description
Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

From Melanocytes to Melanoma

From Melanocytes to Melanoma PDF Author: Vincent J. Hearing
Publisher: Springer Science & Business Media
ISBN: 159259994X
Category : Medical
Languages : en
Pages : 673

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Book Description
Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

Cutaneous Melanoma

Cutaneous Melanoma PDF Author: Charles M. Balch
Publisher: Springer
ISBN: 9783030050689
Category : Medical
Languages : en
Pages : 0

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Book Description
Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the definitive and most authoritative textbook on melanoma used worldwide. Providing the most up-to-date and comprehensive information needed for the clinical management and scientific study of melanoma, Cutaneous Melanoma, 6th edition covers everything from precursors of melanoma to advanced stages of metastatic disease.

Histological Diagnosis of Nevi and Melanoma

Histological Diagnosis of Nevi and Melanoma PDF Author: Guido Massi
Publisher: Springer Science & Business Media
ISBN: 3642373119
Category : Medical
Languages : en
Pages : 764

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Book Description
The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.

Cutaneous Melanoma

Cutaneous Melanoma PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Structure and Control of the Melanocyte

Structure and Control of the Melanocyte PDF Author: G. Della Porta
Publisher: Springer Science & Business Media
ISBN: 3642999069
Category : Medical
Languages : en
Pages : 409

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Book Description
The first five International Pigment Cell Conferences have all been held in U.S.A., from 1948 to 1961. The late MYRON GORDON (1899-1959), was one of their initiators and was the person who was able to give a skillful continuity to these Conferences which have permitted a gathering together of the multiple aspects of investigations in pigment cell biology, including the clinical problem of melanomas. During the International Cancer Congress in Moscow, in 1962, mem bers of the Oncological Research Institute in Sofia offered to organize the Sixth Pigment Cell Conference. Because of their interest and experience in the field of experimental and human melanomas, this seemed highly appropriate. The International Union Against Cancer agreed to sponsor the Conference, since one of the final goals of studies in pigment cell bio logy is certainly the control of the neoplastic deviation of the melanocyte. Thus, for the first time, the Pigment Cell Conference was held in Europe. After discussions with various investigators, the Program Com mittee decided to limit somewhat the chemical and biological part of the program in order to allow relatively more space to electron microscopy of the melanocyte, biology of experimental melanomas, and epidemiology and clinical aspects of human melanomas.

From Melanocytes to Melanoma

From Melanocytes to Melanoma PDF Author: Vincent J. Hearing
Publisher: Humana
ISBN: 9781588294593
Category : Medical
Languages : en
Pages : 678

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Book Description
Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

Pathology of Melanocytic Tumors E-Book

Pathology of Melanocytic Tumors E-Book PDF Author: Klaus J. Busam
Publisher: Elsevier Health Sciences
ISBN: 0323508685
Category : Medical
Languages : en
Pages : 608

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Book Description
Constituting a large percentage of everyday diagnostic practice, melanocytic pathology is a complex and challenging area with many difficult-to-diagnose lesions. This highly illustrated reference, written by three of the world’s leading dermatopathologists, provides authoritative guidance in the accurate diagnosis of even the most challenging pigmented skin tumors, helping you avoid pitfalls and recognize mimics. Covers nearly every variant of melanocytic tumors you’re likely to see. Emphasizes how to arrive at an efficient, accurate diagnosis, and includes dermoscopic findings for optimal diagnostic precision. Discusses modern analytic techniques (cytogenetics, molecular studies) and how to use them for diagnosis. Includes numerous case examples to illustrate the differential diagnoses and work-up; how to use ancillary techniques, along with their pros, cons, and limitations; and clinical follow-up. Presents the knowledge and experience of Klaus Busam, Pedram Gerami, and Richard Scolyer, – three dermatopathologists who are globally renowned for their expertise in melanoma pathology and analysis of melanocytic tumors by modern ancillary diagnostic techniques.

Sunlight, Vitamin D and Skin Cancer

Sunlight, Vitamin D and Skin Cancer PDF Author: Jörg Reichrath
Publisher: Springer Nature
ISBN: 3030462277
Category : Medical
Languages : en
Pages : 428

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Book Description
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.

Pathology of Melanocytic Nevi and Malignant Melanoma

Pathology of Melanocytic Nevi and Malignant Melanoma PDF Author: Michael Piepkorn
Publisher: Springer Science & Business Media
ISBN: 0387216197
Category : Medical
Languages : en
Pages : 432

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Book Description
Highly acclaimed and considered the leading reference in the field, Pathology of Melanocytic Nevi and Malignant Melanoma has now been fully revised and updated to accomodate rapid advances in the field of melanoma pathology. Drs. Michael Piepkorn and Klaus Busam have now joined Dr. Barnhill, world-renowned expert in dermatology and pathology, to expand the text with new sections on the genetics and cytogenetics of melanoma, sentinal lymph node biopsy, the new AJCC TNM staging system for melanoma, the mechanisms of melanoma metastasis. The successful focus and format of the first edition have been preserved. Each lesion and diagnosis is clearly illustrated, now with more than 340 new, digitally enhanced full-color photomicrographs and over 125 tables. A corresponding precis, or concise description of the clinical features, histopathology, differential diagnosis, and outstanding characteristics of each lesion provides readers with a quick yet comprehensive overview of each topic covered. With the inclusion of recent advances in cancer research and new techniques, the second edition of Pathology of Melanocytic Nevi and Malignant Melanoma is the essential reference for every practicing dermatopathologist, pathologist, dermatologist, and cancer research scientist today.

Skin Cancer and UV Radiation

Skin Cancer and UV Radiation PDF Author: Peter Altmeyer
Publisher: Springer Science & Business Media
ISBN: 3642607713
Category : Medical
Languages : en
Pages : 1476

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Book Description
UV radiation is recognized as the major risk factor for skin can cer. For the last three decades the incidence and mortality of skin cancer have been increasing steadily in almost all parts of the world. Unfortunately, there have been very few advances in the management and treatment of skin cancer. In comparison to other malignant tumors, skin cancer offers the unique opportuni ty to identify this tumor at an early stage. Thus, there is strong interest in preventing death by early diagnosis and prompt treat ment. The proceedings of the International Congress on Skin Cancer and UV Radiation which was held in Bochum Germany in October 1996, reflect the newest scientific standards in the field of skin cancer. The conference in Bochum was a platform for leading scientists from all over the world to discuss the complexity and diversity of UV radiation in its interaction with the skin. Starting with basic science like physiology, immunology, and molecular biochemistry of the skin as influenced by UV radiati on, the book presents a profound survey into the field of skin can cer by focusing on the latest scientific results in prevention, early detection, treatment, and epidemiology. The congress in Bochum in 1996 was organized to provide a starting point for coordinated European strategies against skin cancer with internationally renown scientists.