Formation of Intracardiac Electrograms under Physiological and Pathological Conditions

Formation of Intracardiac Electrograms under Physiological and Pathological Conditions PDF Author: Keller, Matthias
Publisher: KIT Scientific Publishing
ISBN: 3731502283
Category : Technology & Engineering
Languages : en
Pages : 264

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Book Description
This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis.

Formation of Intracardiac Electrograms Under Physiological and Pathological Conditions

Formation of Intracardiac Electrograms Under Physiological and Pathological Conditions PDF Author: Matthias Keller
Publisher:
ISBN: 9781013281778
Category : Medical
Languages : en
Pages : 256

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Book Description
This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Characterizing Cardiac Electrophysiology during Radiofrequency Ablation : An Integrative Ex vivo, In silico, and In vivo Approach

Characterizing Cardiac Electrophysiology during Radiofrequency Ablation : An Integrative Ex vivo, In silico, and In vivo Approach PDF Author: Pollnow, Stefan
Publisher: KIT Scientific Publishing
ISBN: 3731508869
Category :
Languages : en
Pages : 296

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Book Description


A Multiscale In Silico Study to Characterize the Atrial Electrical Activity of Patients With Atrial Fibrillation : A Translational Study to Guide Ablation Therapy

A Multiscale In Silico Study to Characterize the Atrial Electrical Activity of Patients With Atrial Fibrillation : A Translational Study to Guide Ablation Therapy PDF Author: Sánchez Arciniegas, Jorge Patricio
Publisher: KIT Scientific Publishing
ISBN: 3731511703
Category : Medical
Languages : en
Pages : 162

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Book Description
The atrial substrate undergoes electrical and structural remodeling during atrial fibrillation. Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. Also, wave propagation direction was tracked from unannotated electrograms. In conclusion, in silico experiments provide insight into electrograms' information of the substrate.

ECG Imaging of Ventricular Activity in Clinical Applications

ECG Imaging of Ventricular Activity in Clinical Applications PDF Author: Schulze, Walther H. W.
Publisher: KIT Scientific Publishing
ISBN: 3731503743
Category : Technology (General)
Languages : en
Pages : 238

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Book Description
ECG imaging was performed in humans to reconstruct ventricular activation patterns and localize their excitation origins. The precision of the non-invasive reconstructions was evaluated against invasive measurements and found to be in line with the state-of-the-art literature. Statistics were produced for various excitation origins and reveal the beat-to-beat robustness of the imaging method.

Multiscale Cohort Modeling of Atrial Electrophysiology : Risk Stratification for Atrial Fibrillation through Machine Learning on Electrocardiograms

Multiscale Cohort Modeling of Atrial Electrophysiology : Risk Stratification for Atrial Fibrillation through Machine Learning on Electrocardiograms PDF Author: Nagel, Claudia
Publisher: KIT Scientific Publishing
ISBN: 3731512815
Category :
Languages : en
Pages : 280

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Book Description
An early detection and diagnosis of atrial fibrillation sets the course for timely intervention to prevent potentially occurring comorbidities. Electrocardiogram data resulting from electrophysiological cohort modeling and simulation can be a valuable data resource for improving automated atrial fibrillation risk stratification with machine learning techniques and thus, reduces the risk of stroke in affected patients.

Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves

Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves PDF Author: Loewe, Axel
Publisher: KIT Scientific Publishing
ISBN: 3731505282
Category :
Languages : en
Pages : 344

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Book Description


Electrophysiologic Testing

Electrophysiologic Testing PDF Author: Richard N. Fogoros
Publisher: John Wiley & Sons
ISBN: 0470750243
Category : Medical
Languages : en
Pages : 307

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Book Description
Following the huge success of previous editions,Electrophysiological Testing 4th edition is the must haveresource for students, residents, cardiology fellows, primary carephysicians, cardiologists, nurses, and technicians becauseit: clarifies the role of electrophysiology in the evaluation ofcardiac arrhythmias discusses advances in therapeutic electrophysiology keeping youcompletely up to date provides clear summaries of complex topics is written in a user-friendly and understandable writing styleto make the information easy to digest and recall includes an entirely new chapter on the key field of CardiacResynchronisation Reviews of previous edition: “Many times I have found that EP literature is verytied to research results and bogs down the primary topic and makesit difficult to understand. This book explains EP in plain English!I think it is in a class by itself." EP Technician, GalichiaHeart Hospital, Wichita, KS, USA "It gives a good understanding of EP without getting tootechnical and complex in the explanations. It accomplishes a majortask of “demystifying” the field of EP. It not onlyaddresses the needs of non technical EP Personnel, but alsoprovides a precise overview of EP for general review.”Cardiac NP, St. Jude's Medical Center

Computational Methods in Cardiac Electrophysiology

Computational Methods in Cardiac Electrophysiology PDF Author: Matthijs Cluitmans
Publisher: Frontiers Media SA
ISBN: 2832529259
Category : Science
Languages : en
Pages : 229

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Book Description


Electrocardiographic Imaging

Electrocardiographic Imaging PDF Author: Maria S. Guillem
Publisher: Frontiers Media SA
ISBN: 2889636712
Category :
Languages : en
Pages : 178

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Book Description
Electrical activity in the myocardium coordinates the contraction of the heart, and its knowledge could lead to a better understanding, diagnosis, and treatment of cardiac diseases. This electrical activity generates an electromagnetic field that propagates outside the heart and reaches the human torso surface, where it can be easily measured. Classical electrocardiography aims to interpret the 12-lead electrocardiogram (ECG) to determine cardiac activity and support the diagnosis of cardiac pathologies such as arrhythmias, altered activations, and ischemia. More recently, a higher number of leads is used to reconstruct a more detailed quantitative description of the electrical activity in the heart by solving the so-called inverse problem of electrocardiography. This technique is known as ECG imaging. Today, clinical applications of ECG imaging are showing promising results in guiding a variety of electrophysiological interventions such as catheter ablation of atrial fibrillation and ventricular tachycardia. However, in order to promote the adoption of ECG imaging in the routine clinical practice, further research is required regarding more accurate mathematical methods, further scientific validation under different preclinical scenarios and a more extensive clinical validation