Author:
Publisher:
ISBN:
Category : Ophthalmology
Languages : en
Pages : 456
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Author: F. Rintelen
Publisher:
ISBN:
Category : Ophthalmology
Languages : en
Pages :
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Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author:
Publisher:
ISBN:
Category : Research
Languages : en
Pages : 490
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Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1516
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Book Description
A keyword listing of serial titles currently received by the National Library of Medicine.
Author: S. Mishima
Publisher: Wayenborgh Publishing
ISBN: 9062998992
Category : Medical
Languages : en
Pages : 466
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Book Description
Author: Atish S Mundada
Publisher: Smithers Rapra
ISBN: 1847355641
Category : Medical
Languages : en
Pages : 210
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Book Description
The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological and anatomical constraints only a small fraction of the drug, effectively 1% or even less of the instilled dose is ocularly absorbed. The effective dose of medication administered ophthalmically may be altered by increasing the retention time of medication in contact with the surface of the eye. To date, Pharmaceutical Technologists have tried to develop different novel formulations like gel, ocular inserts, collagen shields, implants, liposomes, nanoparticles, penetration enhancers and in-situ gelling systems, in order to increase the bioavailability and duration of the therapeutic action of ocular drugs and polymers plays an important role in all these approaches. This book provides detailed information regarding all such polymers which have been used and shown to be excellent in improving the bioavailability of ocular drugs.
Author: Alan F. Wright
Publisher: CRC Press
ISBN: 9783718654932
Category : Medical
Languages : en
Pages : 554
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Book Description
Molecular Genetics of Inherited Eye Disorders provides an authoritative and up-to-date account of molecular genetic advances in a wide spectrum of genetic eye disorders, and forms the second volume in the Modern Genetics book series. The field has produced some dramatic and often unexpected findings in recent years ranging from the elegant unravelling of the molecular basis of colour vision defects to the subtle complexity of the retinoblastoma gene. The role of crystallins in congenital cataract and of the rhodopsin molecule in retinitis pigmentosa are discussed, illustrating the importance of the candidate gene approach to genetic eye disease. Reverse genetic approaches to the cloning of genes responsible for aniridia and choroideremia exemplify the power of the new genetic techniques and signal the start of the next experimental phase, in which the functional characterization of identified genes begins.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :
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Author: Andrew G Lee
Publisher: World Scientific Publishing Company
ISBN: 9814578797
Category : Medical
Languages : en
Pages : 278
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Book Description
The book presents the most common problems seen in neuro-ophthalmology in a case-based learning format that provides rapid access and is easy to read. The user friendly format guides and stimulates the reader to identify the distinctive symptoms in the main complaint and history; to define the differentiating signs on neuro-ophthalmic exam; and to describe the key laboratory or neuroimaging in specific entities. It also challenges the reader to ask additional questions of themselves and others by providing an initial set of questions and answers on specific neuro-ophthalmologic topics.The questions chosen are meant to simulate “real world” questions in the clinic; the answers given serve to provide both the rationale for the correct answer and the explanations or reasons for the incorrect but plausible answers that might distract or mislead a clinician in specific neuro-ophthalmic cases.