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Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0
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Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0
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Book Description
Author: Upper Mississippi River Comprehensive Basin Study Coordinating Committee
Publisher:
ISBN:
Category : Water resources development
Languages : en
Pages : 1072
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Book Description
Author: Jacques W. Delleur
Publisher: CRC Press
ISBN: 1420006002
Category : Technology & Engineering
Languages : en
Pages : 1342
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Book Description
A complete treatment of the theory and practice of groundwater engineering, The Handbook of Groundwater Engineering, Second Edition provides a current and detailed review of how to model the flow of water and the transport of contaminants both in the unsaturated and saturated zones, covers the production of groundwater and the remediation of contaminated groundwater.
Author: Marilyn J. Cipolla
Publisher: Biota Publishing
ISBN: 1615047239
Category : Medical
Languages : en
Pages : 82
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Book Description
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 1786
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Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 1020
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Author: Geological Survey (U.S.)
Publisher:
ISBN:
Category : Geology
Languages : en
Pages : 584
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Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241210281
Category : Business & Economics
Languages : en
Pages : 303
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Book Description
The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensusbuilding process. The following new guidelines were adopted and recommended for use: Procedure for development of the WHO medicines quality assurance guidelines; Guidelines on Good Manufacturing Practices (GMP) for heating ventilation and air-conditioning systems (HVAC) ? illustrative part; Guidance on GMP for Validation including the general main text analytical procedure validation validation of computerized systems and qualification; in the area of interchangeability of multisource medicines: the Protocol to conduct equilibrium solubility experiments for the purpose of biopharmaceutics classification systembased classification of active pharmaceutical ingredients for biowaiver; Guidelines on Import Procedures for pharmaceutical products; and the Good Practice Guidance document on implementing the collaborative procedures. All of the above are included in this report and recommended for implementation.
Author:
Publisher:
ISBN:
Category : Patents
Languages : en
Pages : 2278
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Author:
Publisher:
ISBN:
Category : Energy development
Languages : en
Pages : 1062
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Book Description
