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Author: Patrick Royston
Publisher: Stata Press
ISBN: 9781597180795
Category : Mathematics
Languages : en
Pages : 0
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Book Description
Through real-world case studies, this book shows how to use Stata to estimate a class of flexible parametric survival models. It discusses the modeling of time-dependent and continuous covariates and looks at how relative survival can be used to measure mortality associated with a particular disease when the cause of death has not been recorded. The book describes simple quantification of differences between any two covariate patterns through calculation of time-dependent hazard ratios, hazard differences, and survival differences.
Author: Patrick Royston
Publisher: Stata Press
ISBN: 9781597180795
Category : Mathematics
Languages : en
Pages : 0
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Book Description
Through real-world case studies, this book shows how to use Stata to estimate a class of flexible parametric survival models. It discusses the modeling of time-dependent and continuous covariates and looks at how relative survival can be used to measure mortality associated with a particular disease when the cause of death has not been recorded. The book describes simple quantification of differences between any two covariate patterns through calculation of time-dependent hazard ratios, hazard differences, and survival differences.
Author: Takeshi Emura
Publisher: Springer
ISBN: 9811335168
Category : Medical
Languages : en
Pages : 126
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Book Description
This book introduces readers to advanced statistical methods for analyzing survival data involving correlated endpoints. In particular, it describes statistical methods for applying Cox regression to two correlated endpoints by accounting for dependence between the endpoints with the aid of copulas. The practical advantages of employing copula-based models in medical research are explained on the basis of case studies. In addition, the book focuses on clustered survival data, especially data arising from meta-analysis and multicenter analysis. Consequently, the statistical approaches presented here employ a frailty term for heterogeneity modeling. This brings the joint frailty-copula model, which incorporates a frailty term and a copula, into a statistical model. The book also discusses advanced techniques for dealing with high-dimensional gene expressions and developing personalized dynamic prediction tools under the joint frailty-copula model. To help readers apply the statistical methods to real-world data, the book provides case studies using the authors’ original R software package (freely available in CRAN). The emphasis is on clinical survival data, involving time-to-tumor progression and overall survival, collected on cancer patients. Hence, the book offers an essential reference guide for medical statisticians and provides researchers with advanced, innovative statistical tools. The book also provides a concise introduction to basic multivariate survival models.
Author: Kris Bogaerts
Publisher: CRC Press
ISBN: 1351643053
Category : Mathematics
Languages : en
Pages : 537
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Book Description
Survival Analysis with Interval-Censored Data: A Practical Approach with Examples in R, SAS, and BUGS provides the reader with a practical introduction into the analysis of interval-censored survival times. Although many theoretical developments have appeared in the last fifty years, interval censoring is often ignored in practice. Many are unaware of the impact of inappropriately dealing with interval censoring. In addition, the necessary software is at times difficult to trace. This book fills in the gap between theory and practice. Features: -Provides an overview of frequentist as well as Bayesian methods. -Include a focus on practical aspects and applications. -Extensively illustrates the methods with examples using R, SAS, and BUGS. Full programs are available on a supplementary website. The authors: Kris Bogaerts is project manager at I-BioStat, KU Leuven. He received his PhD in science (statistics) at KU Leuven on the analysis of interval-censored data. He has gained expertise in a great variety of statistical topics with a focus on the design and analysis of clinical trials. Arnošt Komárek is associate professor of statistics at Charles University, Prague. His subject area of expertise covers mainly survival analysis with the emphasis on interval-censored data and classification based on longitudinal data. He is past chair of the Statistical Modelling Society and editor of Statistical Modelling: An International Journal. Emmanuel Lesaffre is professor of biostatistics at I-BioStat, KU Leuven. His research interests include Bayesian methods, longitudinal data analysis, statistical modelling, analysis of dental data, interval-censored data, misclassification issues, and clinical trials. He is the founding chair of the Statistical Modelling Society, past-president of the International Society for Clinical Biostatistics, and fellow of ISI and ASA.
Author: Jonathan H. Turner
Publisher: Routledge
ISBN: 1000213757
Category : Social Science
Languages : en
Pages : 234
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Book Description
In this book, Jonathan H. Turner combines sociology, evolutionary biology, cladistic analysis from biology, and comparative neuroanatomy to examine human nature as inherited from common ancestors shared by humans and present-day great apes. Selection pressures altered this inherited legacy for the ancestors of humans—termed hominins for being bipedal—and forced greater organization than extant great apes when the hominins moved into open-country terrestrial habitats. The effects of these selection pressures increased hominin ancestors’ emotional capacities through greater social and group orientation. This shift, in turn, enabled further selection for a larger brain, articulated speech, and culture along the human line. Turner elaborates human nature as a series of overlapping complexes that are the outcome of the inherited legacy of great apes being fed through the transforming effects of a larger brain, speech, and culture. These complexes, he shows, can be understood as the cognitive complex, the psychological complex, the emotions complex, the interaction complex, and the community complex.
Author: Peter F. Thall
Publisher: CRC Press
ISBN: 1040026710
Category : Mathematics
Languages : en
Pages : 711
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Book Description
Bayesian Precision Medicine presents modern Bayesian statistical models and methods for identifying treatments tailored to individual patients using their prognostic variables and predictive biomarkers. The process of evaluating and comparing treatments is explained and illustrated by practical examples, followed by a discussion of causal analysis and its relationship to statistical inference. A wide array of modern Bayesian clinical trial designs are presented, including applications to many oncology trials. The later chapters describe Bayesian nonparametric regression analyses of datasets arising from multistage chemotherapy for acute leukemia, allogeneic stem cell transplantation, and targeted agents for treating advanced breast cancer. Features: Describes the connection between causal analysis and statistical inference Reviews modern personalized Bayesian clinical trial designs for dose-finding, treatment screening, basket trials, enrichment, incorporating historical data, and confirmatory treatment comparison, illustrated by real-world applications Presents adaptive methods for clustering similar patient subgroups to improve efficiency Describes Bayesian nonparametric regression analyses of real-world datasets from oncology Provides pointers to software for implementation Bayesian Precision Medicine is primarily aimed at biostatisticians and medical researchers who desire to apply modern Bayesian methods to their own clinical trials and data analyses. It also might be used to teach a special topics course on precision medicine using a Bayesian approach to postgraduate biostatistics students. The main goal of the book is to show how Bayesian thinking can provide a practical scientific basis for tailoring treatments to individual patients.
Author: Chris Hann
Publisher: John Wiley & Sons
ISBN: 0745699391
Category : Social Science
Languages : en
Pages : 161
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Book Description
This book is a new introduction to the history and practice of economic anthropology by two leading authors in the field. They show that anthropologists have contributed to understanding the three great questions of modern economic history: development, socialism and one-world capitalism. In doing so, they connect economic anthropology to its roots in Western philosophy, social theory and world history. Up to the Second World War anthropologists tried and failed to interest economists in their exotic findings. They then launched a vigorous debate over whether an approach taken from economics was appropriate to the study of non-industrial economies. Since the 1970s, they have developed a critique of capitalism based on studying it at home as well as abroad. The authors aim to rejuvenate economic anthropology as a humanistic project at a time when the global financial crisis has undermined confidence in free market economics. They argue for the continued relevance of predecessors such as Marcel Mauss and Karl Polanyi, while offering an incisive review of recent work in this field. Economic Anthropology is an excellent introduction for social science students at all levels, and it presents general readers with a challenging perspective on the world economy today. Selected by Choice as a 2013 Outstanding Academic Title
Author: Shannon Lee Dawdy
Publisher: University of Chicago Press
ISBN: 0226138437
Category : Social Science
Languages : en
Pages : 344
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Book Description
Building the Devil’s Empire is the first comprehensive history of New Orleans’s early years, tracing the town’s development from its origins in 1718 to its revolt against Spanish rule in 1768. Shannon Lee Dawdy’s picaresque account of New Orleans’s wild youth features a cast of strong-willed captives, thin-skinned nobles, sharp-tongued women, and carousing travelers. But she also widens her lens to reveal the port city’s global significance, examining its role in the French Empire and the Caribbean, and she concludes that by exemplifying a kind of rogue colonialism—where governments, outlaws, and capitalism become entwined—New Orleans should prompt us to reconsider our notions of how colonialism works. "[A] penetrating study of the colony's founding."—Nation “A brilliant and spirited reinterpretation of the emergence of French New Orleans. Dawdy leads us deep into the daily life of the city, and along the many paths that connected it to France, the North American interior, and the Greater Caribbean. A major contribution to our understanding of the history of the Americas and of the French Atlantic, the work is also a model of interdisciplinary research and analysis, skillfully bringing together archival research, archaeology, and literary analysis.”—Laurent Dubois, Duke University
Author: Geoff Williams
Publisher: Bloomsbury Publishing
ISBN: 1441184589
Category : Language Arts & Disciplines
Languages : en
Pages : 279
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Book Description
This book presents a unique range of interdisciplinary work on questions of language development and evolution. It makes visible the significant contribution which meaning-oriented linguistics is making to debates about the origins of language - from the perspective of language evolution in the species as well as language development in the child. As well as linguistics in the systemic functional, or Hallidayan, tradition, the book offers contributions from primatology, psychiatry, sociology and education.
Author: Gina Perez
Publisher: Univ of California Press
ISBN: 9780520936416
Category : Social Science
Languages : en
Pages : 300
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Book Description
In The Near Northwest Side Story, Gina M. Pérez offers an intimate and unvarnished portrait of Puerto Rican life in Chicago and San Sebastian, Puerto Rico—two places connected by a long history of circulating people, ideas, goods, and information. Pérez's masterful blend of history and ethnography explores the multiple and gendered reasons for migration, why people maintain transnational connections with distant communities, and how poor and working-class Puerto Ricans work to build meaningful communities. Pérez traces the changing ways that Puerto Ricans have experienced poverty, displacement, and discrimination and illustrates how they imagine and build extended families and dense social networks that link San Sebastian to barrios in Chicago. She includes an incisive analysis of the role of the state in shaping migration through such projects as the Chardon Plan, Operation Bootstrap, and the Chicago Experiment. The Near Northwest Side Story provides a unique window on the many strategies people use to resist the negative consequences of globalization, economic development, and gentrification.
Author: George Edward Milne
Publisher: University of Georgia Press
ISBN: 0820347507
Category : History
Languages : en
Pages : 313
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Book Description
"This manuscript focuses on the interactions between Native Americans and European colonists during the seventeenth and eighteenth centuries, particularly the relationships that developed between the French and the Natchez, Chickasaw, and Choctaw peoples. Milne's history of the Lower Mississippi Valley and its peoples provides the most comprehensive and detailed account of the Natchez in particular, from La Salle's first encounter with what would become Louisiana to the ultimate disappearance of the Natchez by the end of the 1730s. In crafting this narrative, George Milne also analyzes the ways in which French attitudes about race and slavery influenced native North American Indians in the vicinity of French colonial settlements on the Gulf coast, and how in turn Native Americans adopted and/or resisted colonial ideology"--
