Fast Quantitative Magnetic Resonance Imaging

Fast Quantitative Magnetic Resonance Imaging PDF Author: Guido Buonincontri
Publisher: Morgan & Claypool Publishers
ISBN: 1681736950
Category : Medical
Languages : en
Pages : 142

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Book Description
Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (qMRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of qMRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of qMRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections. Recently, new methods for rapid qMRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (syMRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques. Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy.

Theory of Quantitative Magnetic Resonance Imaging

Theory of Quantitative Magnetic Resonance Imaging PDF Author: Hernán Jara
Publisher: World Scientific Publishing Company
ISBN: 9814518387
Category : Technology & Engineering
Languages : en
Pages : 264

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Book Description
qMRI is a rapidly evolving scientific field of high current interest because it has the potential of radically changing the clinical and research practices of magnetic resonance imaging (MRI). This focuses solely on the theoretical aspects of qMRI, which are treated and analyzed at three different spatial scales, specifically: i) the quantum physics scale of individual spins; ii) the semi-classical physics scale of spin packets; and iii) the imaging scale of voxels. Topics are presented paying particular attention to theoretical unification and mathematical uniformity.

Quantitative Magnetic Resonance Imaging

Quantitative Magnetic Resonance Imaging PDF Author: Nicole Seiberlich
Publisher: Academic Press
ISBN: 0128170581
Category : Computers
Languages : en
Pages : 1094

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Book Description
Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Fast Quantitative Magnetic Resonance Imaging

Fast Quantitative Magnetic Resonance Imaging PDF Author: Guido Buonincontri
Publisher: Morgan & Claypool Publishers
ISBN: 1681736950
Category : Medical
Languages : en
Pages : 142

Get Book Here

Book Description
Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (qMRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of qMRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of qMRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections. Recently, new methods for rapid qMRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (syMRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques. Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy.

Quantitative MRI of the Brain

Quantitative MRI of the Brain PDF Author: Mara Cercignani
Publisher: CRC Press
ISBN: 9781138032859
Category : Brain
Languages : en
Pages : 342

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Book Description
Cover -- Title Page -- Copyright Page -- Table of Contents -- Foreword -- Foreword to the First Edition -- Editors -- Contributors -- Introduction -- Introduction to the First Edition -- 1 Concepts: Measurement in MRI -- 2 Measurement Process: MR Data Collection and Image Analysis -- 3 Quality Assurance: Accuracy, Precision, Controls and Phantoms -- 4 PD: Proton Density of Tissue Water -- 5 T1: Longitudinal Relaxation Time -- 6 T2: Transverse Relaxation Time -- 7 T2*: Susceptibility Weighted Imaging and Quantitative Susceptibility Mapping -- 8 D: The Diffusion of Water (DTI) -- 9 Advanced Diffusion Models -- 10 MT: Magnetisation Transfer -- 11 CEST: Chemical Exchange Saturation Transfer -- 12 MRS: 1H Spectroscopy -- 13 Multinuclear MR Imaging and Spectroscopy -- 14 T1-Weighted DCE MRI -- 15 Functional and Metabolic MRI -- 16 ASL: Blood Perfusion Measurement Using Arterial Spin Labelling -- 17 Image Analysis -- 18 Future of Quantitative MRI -- Appendix A: Greek Alphabet for Scientific Use -- Appendix B: MRI Abbreviations and Acronyms -- Index

Quantitative Image Quality Evaluation of Fast Magnetic Resonance Imaging

Quantitative Image Quality Evaluation of Fast Magnetic Resonance Imaging PDF Author: Donglai Huo
Publisher:
ISBN:
Category :
Languages : en
Pages : 186

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Book Description


Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis

Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis PDF Author: Massimo Filippi
Publisher: Springer Science & Business Media
ISBN: 9788847000414
Category : Medical
Languages : en
Pages : 216

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Book Description
The therapeutic era for MS has begun, and many new, potentially effective treatments are now available. MRI offers a range of techniques which are more reliable and sensitive than any other available approach in detecting brain and spinal cord abnormalities, monitoring their evolution, and providing in vivo information about heterogenous pathological substrates of the MS lesions. Readers will find this volume a valuable summary of the state-of- the art, as well as a useful reference text from which to plan future clinical trials in MS.

Magnetic Resonance Imaging

Magnetic Resonance Imaging PDF Author: Marinus T. Vlaardingerbroek
Publisher: Springer Science & Business Media
ISBN: 9783540436812
Category : Mathematics
Languages : en
Pages : 526

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Book Description
Presents an overall analytical treatment of MRI physics and engineering. Special attention is paid to the treatment of intrinsic artefacts of the different sequences which can be described for the different scan methods. The book contains many images, especially showing specific properties of the different scan methods. The methods discussed include RARE, GRASE, EPI and Spiral Scan. The 3rd edition deals with stranger gradient and new RF coil systems, and sequences such as Balanced FFE and q-space diffusion imaging and SENSE.

Computational Molecular Magnetic Resonance Imaging for Neuro-oncology

Computational Molecular Magnetic Resonance Imaging for Neuro-oncology PDF Author: Michael O. Dada
Publisher: Springer Nature
ISBN: 3030767280
Category : Science
Languages : en
Pages : 412

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Book Description
Based on the analytical methods and the computer programs presented in this book, all that may be needed to perform MRI tissue diagnosis is the availability of relaxometric data and simple computer program proficiency. These programs are easy to use, highly interactive and the data processing is fast and unambiguous. Laboratories (with or without sophisticated facilities) can perform computational magnetic resonance diagnosis with only T1 and T2 relaxation data. The results have motivated the use of data to produce data-driven predictions required for machine learning, artificial intelligence (AI) and deep learning for multidisciplinary and interdisciplinary research. Consequently, this book is intended to be very useful for students, scientists, engineers, the medical personnel and researchers who are interested in developing new concepts for deeper appreciation of computational magnetic resonance imaging for medical diagnosis, prognosis, therapy and management of tissue diseases.

Magnetic Resonance Imaging - E-Book

Magnetic Resonance Imaging - E-Book PDF Author: Stewart C. Bushong
Publisher: Elsevier Health Sciences
ISBN: 0323277659
Category : Medical
Languages : en
Pages : 528

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Book Description
Magnetic Resonance Imaging: Physical and Biological Principles, 4th Edition offers comprehensive, well-illustrated coverage on this specialized subject at a level that does not require an extensive background in math and physics. It covers the fundamentals and principles of conventional MRI along with the latest fast imaging techniques and their applications. Beginning with an overview of the fundamentals of electricity and magnetism (Part 1), Parts 2 and 3 present an in-depth explanation of how MRI works. The latest imaging methods are presented in Parts 4 and 5, and the final section (Part 6) covers personnel and patient safety and administration issues. This book is perfect for student radiographers and practicing technologists preparing to take the MRI advanced certification exam offered by the American Registry of Radiologic Technologists (ARRT). "I would recommend it to anyone starting their MRI training and anyone trying to teach MRI to others." Reviewed by RAD Magazine, June 2015 Challenge questions at the end of each chapter help you assess your comprehension. Chapter outlines and objectives assist you in following the hierarchy of material in the text. Penguin boxes highlight key points in the book to help you retain the most important information and concepts in the text. NEW! Two MRI practice exams that mirror the test items in each ARRT category have been added to the end of the text to help you replicate the ARRT exam experience. NEW! Chapter on Partially Parallel Magnetic Resonance Imaging increases the comprehensiveness of the text. NEW! Updated key terms have been added to each chapter with an updated glossary defining each term.

Magnetic Resonance Imaging

Magnetic Resonance Imaging PDF Author: Robert W. Brown
Publisher: John Wiley & Sons
ISBN: 0471720852
Category : Medical
Languages : en
Pages : 976

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Book Description
New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.