Farming Human Pathogens

Farming Human Pathogens PDF Author: Rodrick Wallace
Publisher: Springer Science & Business Media
ISBN: 038792213X
Category : Computers
Languages : en
Pages : 220

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Book Description
Farming Human Pathogens: Ecological Resilience and Evolutionary Process introduces a cutting-edge mathematical formalism based on the asymptotic limit theorems of information theory to describe how punctuated shifts in mesoscale ecosystems can entrain patterns of gene expression and organismal evolution. The authors apply the new formalism toward characterizing a number of infectious diseases that have evolved in response to the world as humans have made it. Many of the human pathogens that are emerging out from underneath epidemiological control are 'farmed' in the metaphorical sense, as the evolution of drug-resistant HIV makes clear, but also quite literally, as demonstrated by avian influenza's emergence from poultry farms in southern China. The most successful pathogens appear able to integrate selection pressures humans have imposed upon them from a variety of socioecological scales. The book also presents a related treatment of Eigen's Paradox and the RNA 'error catastrophe' that bedevils models of the origins of viruses and of biological life itself.

Farming Human Pathogens

Farming Human Pathogens PDF Author: Rodrick Wallace
Publisher: Springer Science & Business Media
ISBN: 038792213X
Category : Computers
Languages : en
Pages : 220

Get Book Here

Book Description
Farming Human Pathogens: Ecological Resilience and Evolutionary Process introduces a cutting-edge mathematical formalism based on the asymptotic limit theorems of information theory to describe how punctuated shifts in mesoscale ecosystems can entrain patterns of gene expression and organismal evolution. The authors apply the new formalism toward characterizing a number of infectious diseases that have evolved in response to the world as humans have made it. Many of the human pathogens that are emerging out from underneath epidemiological control are 'farmed' in the metaphorical sense, as the evolution of drug-resistant HIV makes clear, but also quite literally, as demonstrated by avian influenza's emergence from poultry farms in southern China. The most successful pathogens appear able to integrate selection pressures humans have imposed upon them from a variety of socioecological scales. The book also presents a related treatment of Eigen's Paradox and the RNA 'error catastrophe' that bedevils models of the origins of viruses and of biological life itself.

WHO guidelines on use of medically important antimicrobials in food-producing animals

WHO guidelines on use of medically important antimicrobials in food-producing animals PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241550130
Category : Business & Economics
Languages : en
Pages : 0

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Book Description
WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.

Improving Food Safety Through a One Health Approach

Improving Food Safety Through a One Health Approach PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309259363
Category : Medical
Languages : en
Pages : 418

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Book Description
Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Big Farms Make Big Flu

Big Farms Make Big Flu PDF Author: Rob Wallace
Publisher: NYU Press
ISBN: 1583675906
Category : Business & Economics
Languages : en
Pages : 456

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Book Description
The first collection to explore infectious disease, agriculture, economics, and the nature of science together Thanks to breakthroughs in production and food science, agribusiness has been able to devise new ways to grow more food and get it more places more quickly. There is no shortage of news items on hundreds of thousands of hybrid poultry—each animal genetically identical to the next—packed together in megabarns, grown out in a matter of months, then slaughtered, processed and shipped to the other side of the globe. Less well known are the deadly pathogens mutating in, and emerging out of, these specialized agro-environments. In fact, many of the most dangerous new diseases in humans can be traced back to such food systems, among them Campylobacter, Nipah virus, Q fever, hepatitis E, and a variety of novel influenza variants. Agribusiness has known for decades that packing thousands of birds or livestock together results in a monoculture that selects for such disease. But market economics doesn't punish the companies for growing Big Flu—it punishes animals, the environment, consumers, and contract farmers. Alongside growing profits, diseases are permitted to emerge, evolve, and spread with little check. “That is,” writes evolutionary biologist Rob Wallace, “it pays to produce a pathogen that could kill a billion people.” In Big Farms Make Big Flu, a collection of dispatches by turns harrowing and thought-provoking, Wallace tracks the ways influenza and other pathogens emerge from an agriculture controlled by multinational corporations. Wallace details, with a precise and radical wit, the latest in the science of agricultural epidemiology, while at the same time juxtaposing ghastly phenomena such as attempts at producing featherless chickens, microbial time travel, and neoliberal Ebola. Wallace also offers sensible alternatives to lethal agribusiness. Some, such as farming cooperatives, integrated pathogen management, and mixed crop-livestock systems, are already in practice off the agribusiness grid. While many books cover facets of food or outbreaks, Wallace's collection appears the first to explore infectious disease, agriculture, economics and the nature of science together. Big Farms Make Big Flu integrates the political economies of disease and science to derive a new understanding of the evolution of infections. Highly capitalized agriculture may be farming pathogens as much as chickens or corn.

Encyclopedia of Food Security and Sustainability

Encyclopedia of Food Security and Sustainability PDF Author:
Publisher: Elsevier
ISBN: 0128126884
Category : Technology & Engineering
Languages : en
Pages : 1861

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Book Description
The Encyclopedia of Food Security and Sustainability, Three Volume Set covers the hottest topics in the science of food sustainability, providing a synopsis of the path society is on to secure food for a growing population. It investigates the focal issue of sustainable food production in relation to the effects of global change on food resources, biodiversity and global food security. This collection of methodological approaches and knowledge derived from expert authors around the world offers the research community, food industry, scientists and students with the knowledge to relate to, and report on, the novel challenges of food production and sustainability. This comprehensive encyclopedia will act as a platform to show how an interdisciplinary approach and closer collaboration between the scientific and industrial communities is necessary to strengthen our existing capacity to generate and share research data. Offers readers a ‘one-stop’ resource on the topic of food security and sustainability Contains articles split into sections based on the various dimensions of Food Security and Food Sustainability Written by academics and practitioners from various fields and regions with a “farm to fork understanding Includes concise and accessible chapters, providing an authoritative introduction for non-specialists and readers from undergraduate level upwards, as well as up-to-date foundational content for those familiar with the field

The Use of Drugs in Food Animals

The Use of Drugs in Food Animals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309175771
Category : Medical
Languages : en
Pages : 276

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Book Description
The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.

On-Farm Biodiversity as a Tool to Suppress Foodborne Human Pathogens

On-Farm Biodiversity as a Tool to Suppress Foodborne Human Pathogens PDF Author: Matthew Steven Jones
Publisher:
ISBN:
Category : Agrobiodiversity
Languages : en
Pages : 172

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Book Description
Farmland biodiversity generally benefits pollination, biological control, and other key ecosystem services. Food safety has been seen as an exception to this broader pattern, as diverse farmlands can attract wildlife that vector foodborne human pathogens. Resulting mitigation efforts thus often seek to deter wildlife by removing natural habitats, while also excluding vertebrate livestock. However, surprising recent evidence suggests that farm simplification actually increases the likelihood that produce will be contaminated with human pathogens. In this dissertation, I introduce readers to my research focus in Chapter 1 and review the impact of arthropod biodiversity on ecosystem services in Chapter 2. In Chapter 3, I consider the possibility that intensified agriculture harms feces-feeding (coprophagous) beetles and bacteria, which may contribute to heightened food safety risk. I found that organic and integrated crop-livestock management encourage Escherichia coli suppressive species better than conventional management. In Chapter 4, I examine the role of dung beetles in suppressing pathogen-transmitting flies. I found that dung beetles reduce vector emergence and subsequently, the amount of pathogenic E. coli which gets transmitted to produce. To better understand the impacts of invasion on dung beetle-mediated ecosystem services, I initiated a long-term study in order to capitalize on the recent dung beetle introductions to NZ and this dataset is reported in Chapter 5. Chapter 6 closes the dissertation with a guide for farmers to better maximize the dung-beetle mediated ecosystem services on their farms throughout the west coast. The approaches presented in this dissertation provide a detailed understanding of several mechanisms underlying how on-farm biodiversity can be used as a tool for ecologically-based pathogen suppression. It is my hope that these chapters might serve as a guide for better incorporating the coprophage community in future agroecological decision-making.

On-farm Strategies to Control Foodborne Pathogens

On-farm Strategies to Control Foodborne Pathogens PDF Author: Todd Riley Callaway
Publisher: Nova Science Publishers
ISBN: 9781621004110
Category : Agriculture
Languages : en
Pages : 0

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Book Description
The economic impact of food-borne illnesses caused by bacteria associated with food animals ranges from $10 to 40 billion (USD) per year, and effects across the EU are similar in scale. Due to the large drain on the GDP, as well as human health and societal impacts, research and regulations over the past 100 years have focused on improving food safety which has resulted in the U.S. and EU currently having the safest food supply in history. Unfortunately, the very safety of the food supply causes increased notice of the sporadic outbreaks of food-borne illness, receiving intensive media coverage and instilling fear and distrust in the public mind in regards to the safety of their food supply. This book encapsulates many of the arenas in which the future improvements in food safety and human health will be explored.

Advancements and Technologies in Pig and Poultry Bacterial Disease Control

Advancements and Technologies in Pig and Poultry Bacterial Disease Control PDF Author: Neil Foster
Publisher: Academic Press
ISBN: 0128182385
Category : Nature
Languages : en
Pages : 278

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Book Description
Advancements and Technologies in Pig and Poultry Bacterial Disease Control provides the most up-to-date knowledge on the tools and technologies used in the economics, prevention, monitoring and control of the most important bacterial diseases in these two important livestock species. Written by international experts in veterinary medicine, veterinary science, agricultural economics and environmental monitoring, this book provides state-of-the-art information regarding the application of technology to the prevention and control of bacterial disease in pigs and poultry. It presents the most up-to-date information on the major bacterial pathogens, why they are important, their epidemiology, pathogenesis and molecular basis of their virulence. Additional sections examine how genomic sequencing addresses the development of disease biomarkers for faster and highly specific diagnosis and how next generation sequencing can identify good and bad microflora. This book will be a valuable resource for veterinarians, epidemiologists, animal scientists, technologists, and researchers studying precision livestock farming. Students in veterinary, animal science and bio-science courses will also find it useful for its coverage of diseases and monitoring tools. Highlights crossover technologies from human to veterinary medicine, including the use of bioinformatics and genomics for disease prevention Uses results from the EU FP7-funded ProHealth project, the largest of its type ever awarded by the EU Examines how genomic analysis via next generation sequencing and microarray platforms can be exploited to develop novel biomarkers of bacterial disease in animals Reports on novel environmental monitoring tools and their use in determining disease threshold levels within herds and flocks

Emerging foodborne pathogens

Emerging foodborne pathogens PDF Author: Yasmine Motarjemi
Publisher: CRC Press
ISBN: 9780849334290
Category : Technology & Engineering
Languages : en
Pages : 664

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Book Description
Developments such as the increasing globalization of the food industry, constant innovations in technologies and products, and changes in the susceptibility of populations to disease have all highlighted the problem of emerging pathogens, either newly discovered through more sensitive analytical methods, linked for the first time to disease in humans, or newly associated with a particular food. Designed for microbiologists and quality assurance professionals and for government and academic food safety scientists, this timely reference discusses ways of identifying emerging pathogens and includes chapters on individual pathogens, their epidemiology, methods of detection, and means of control.