Pre-Clinical Models of PTSD

Pre-Clinical Models of PTSD PDF Author: Israel Liberzon
Publisher: Frontiers Media SA
ISBN: 2889632512
Category :
Languages : en
Pages : 194

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Pre-Clinical Models of PTSD

Pre-Clinical Models of PTSD PDF Author: Israel Liberzon
Publisher: Frontiers Media SA
ISBN: 2889632512
Category :
Languages : en
Pages : 194

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Book Description


The Mineralogical Magazine and Journal of the Mineralogical Society

The Mineralogical Magazine and Journal of the Mineralogical Society PDF Author:
Publisher:
ISBN:
Category : Mineralogy
Languages : en
Pages : 364

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Emotional Modulation of the Synapse

Emotional Modulation of the Synapse PDF Author: Christa McIntyre
Publisher: Frontiers Media SA
ISBN: 2889196062
Category : Neurology
Languages : en
Pages : 137

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Book Description
Highly emotional events tend to be well remembered. The adaptive value in this is clear – those events that have a bearing on survival should be stored for future use as long-term memories whereas memories of inconsequential events would not as likely contribute to future survival. Enduring changes in the structure and function of synapses, neural circuitry, and ultimately behavior, can be modulated by highly aversive or rewarding experiences. In the last decade, the convergence of cellular, molecular, and systems neuroscience has produced new insights into the biological mechanisms that determine whether a memory will be stored for the long-term or lost forever. This Research Topic brings together leading experts, who work at multiple levels of analysis, to reveal recent discoveries and concepts regarding the synaptic mechanisms of consolidation and extinction of emotionally arousing memories.

Reinforcement

Reinforcement PDF Author: R. M. Gilbert
Publisher: Academic Press
ISBN: 1483266249
Category : Psychology
Languages : en
Pages : 303

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Book Description
Reinforcement: Behavioral Analyses covers the proceedings of the 1970 Symposium on Schedule-induced and Schedule-Dependent Phenomena, held in Toronto, Ontario, Canada. This symposium highlights theoretically inclined papers on reinforcement processes. This text contains 10 chapters and begins with a description of how behavior is induced by various environmental events, especially reinforcing events, as well as the relationship between control by inducing stimuli and reinforceability. The subsequent chapters deal with reinforcement phenomena in terms of preference relations and the conditioned emotional responses in terms of opposing motivational processes. These topics are followed by reviews of schedule-dependent effects of preaversive stimuli and the maintenance of behavior by apparent reinforcers that might be expected to punish, as well as the identification of critical variable that underlie the phenomenon. Other chapters examine the interactions between operant and responded conditioning processes. The final chapters outline the experiments on behavior stream whose hallmark is reinforcement if the absence of specified behavior. These chapters emphasize the analogy between the evolution of species and the modification of behavior. This book will be of value to behaviorists and psychologists.

Estrogens and Memory

Estrogens and Memory PDF Author: Karyn M. Frick
Publisher:
ISBN: 0190645903
Category : Medical
Languages : en
Pages : 525

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Book Description
"A book about the influence of estrogens on memory would have been unthinkable as recently as 30 years ago. Although a few small studies in the late 1970's reported a beneficial effect of estrogens on memory in human women (Hackman and Galbraith, 1976; Fedor-Freybergh, 1977), examination of the role of estrogens in memory did not truly capture more widespread attention until the pioneering work of Barbara Sherwin and colleagues in 1988 and beyond. In her initial paper, Sherwin showed that bilateral removal of the ovaries (aka surgical menopause) led to impaired short-term and long-term memory, whereas treatment of surgically menopausal women with estradiol alone, testosterone alone, or estradiol plus testosterone prevented this decline (Sherwin, 1988). As a search for the terms "estrogen" and "memory" in PubMed illustrates, well over 2000 papers have been published on the subject of estrogens and memory in the ensuing decades. The vast majority of these studies have focused on the hippocampus, a bilateral medial temporal lobe structure essential for the formation of episodic memories, particularly those with spatial, contextual, relational, temporal, and recognition components (Olton et al., 1979; Morris et al., 1982; Kim and Fanselow, 1992; Squire, 1992; Cohen and Stackman, 2015; Tonegawa et al., 2015; Eichenbaum, 2017). Although various forms of learning and memory are mediated by numerous brain regions, including the prefrontal cortex, medial temporal lobe cortices, amygdala, striatum, and cerebellum, the hippocampus has received the lion's share of attention due to its central importance for episodic memory formation. Hippocampal damage produces profound retrograde amnesia for facts and events, as well as anterograde amnesia for new information and impairments in spatial navigation (Winocur, 1990; Anagnostaras et al., 2001; Clark et al., 2002; Gilboa et al., 2006). Hippocampal dysfunction in middle-aged and aged subjects is a primary contributor to age-related memory decline (Golumb et al., 1996; Grady et al., 2003; Apostolova et al., 2010; Burke and Barnes, 2010; Small et al., 2011; Yassa et al., 2011), and has also been implicated in the cognitive impairments observed in diseases such as schizophrenia and depression (Small et al., 2011; Nakahara et al., 2018; Santos et al., 2018; Ott et al., 2019). Moreover, the hippocampi of patients with Alzheimer's disease are substantially atrophied and burdened with copious amounts of amyloid plaques and neurofibrillary tangles, the hallmark pathologies of this insidious disease (Hyman et al., 1984; Walsh and Selkoe, 2004; Selkoe and Hardy, 2016). As such, understanding how estrogens influence hippocampal functioning may provide important insights not only about the fundamental neurobiology of memory processes, but also into the etiology of neuropsychiatric and neurodegenerative diseases"--

Mineralogical Magazine

Mineralogical Magazine PDF Author:
Publisher:
ISBN:
Category : Mineralogy
Languages : en
Pages : 356

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Magical Doctor of Life

Magical Doctor of Life PDF Author: Tie BeiLe
Publisher: Funstory
ISBN: 1649917368
Category : Fiction
Languages : en
Pages : 843

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Book Description
Li Yifan, with the Nine Yin Meridians on his body, was able to reach the world with just his hands alone. He had stolen the hearts of countless young girls, and facing the women around him, Li Yifan chuckled and waved his hand, "Come ... Let this Divine Doctor treat your illnesses. "

The Synaptic Basis of Neuropathology

The Synaptic Basis of Neuropathology PDF Author: Fereshteh S. Nugent
Publisher: Frontiers Media SA
ISBN: 2832519784
Category : Science
Languages : en
Pages : 218

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Brain Recyclers

Brain Recyclers PDF Author: J.S. Morin
Publisher: Magical Scrivener Press
ISBN: 1942642261
Category : Fiction
Languages : en
Pages : 351

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Book Description
Immortality is a prison of fear. With humanity out in the open, Eve and her sisters are now the subject of worldwide adoration—and constant surveillance. With Eve as humanity’s spokeswoman, it’s up to her to bargain for the freedom she craves now that’s she’s had a taste of it. But Eve’s pleas fall on deaf ears. Hers is only one voice, lost in a committee of robots hundreds of years her senior. No amount of earnestness can overcome the crushing inertia of the Human Committee. With no prospect of gaining room to breathe within the rules, Eve hatches a plot to escape and finds out exactly why the robots have tried so hard to keep the humans safe. The Brain Recyclers are out there. They want to be human again. They will stop at nothing. Brain Recyclers is the second book in the Robot Geneticists series. For fans of old-school science fiction where robots are people and any problem can be solved (or created) with enough scientists. If you've ever wondered what the world would be like if scientists who'd read I, Robot created a race of robots, or if you ever wondered what might be more dangerous to clone than dinosaurs, this is the series for you.

Rebel Robots

Rebel Robots PDF Author: J.S. Morin
Publisher: Magical Scrivener Press
ISBN: 1942642385
Category : Fiction
Languages : en
Pages : 321

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Book Description
"Never in a thousand years" just expired. Charlie7 has his secrets. Every robot knows that history has a dark period where he was the only one alive, with no one to corroborate his story. That was before an old adversary, long believed dead, emerges from hiding to expose Charlie7 as a fraud. With a newfound internship mixing new robotic personalities, Rachel Eighteen stumbles across an old file in the archive that no robot can access. The data it contains could upset the underpinnings of the thousand-year-old robotic civilization. When rebel forces seize control of the factory and take Rachel prisoner, can she hold out long enough for help to arrive? Does she even want to? What value does the truth have when the lie is all you've ever known? Charlie7, for one, hopes never to find out.