Experimental and Clinical Neurotoxicology PDF Download
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Author: Peter S. Spencer
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 958
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Book Description
Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition, the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text.The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabetical treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index.In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humans and animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.
Author: Peter S. Spencer
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 958
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Book Description
Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition, the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text.The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabetical treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index.In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humans and animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.
Author: Louis W. Chang
Publisher: Elsevier
ISBN: 0080537472
Category : Science
Languages : en
Pages : 875
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Book Description
Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. - Discusses neurobehavioral testing methods for assessment of neural dysfunctions - Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems - Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity - Presents step-by-step procedures for many methods - Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation
Author: Mohamed B. Abou-Donia
Publisher: CRC Press
ISBN: 9781439805428
Category : Medical
Languages : en
Pages : 640
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Book Description
Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology. It discusses neurotoxic agents, describes the methods for studying neurotoxic actions, covers factors affecting neurotoxicity, and inc
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045312
Category : Science
Languages : en
Pages : 167
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Book Description
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Author: National Institute for Occupational Safety and Health
Publisher:
ISBN:
Category : Industrial hygiene
Languages : en
Pages : 238
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Book Description
Current NIOSH grant support for research and demonstration projects. Intended to give information on scope and status of program, as well as to stimulate interest among scientists of related disciplines. Arranged according to subjects. Each entry gives detailed information, e.g., investigator, institution, objective, methodology, significance, and publications resulting from grant. Indexes of investigators and of grantee institutions.
Author: William Slikker Jr.
Publisher: Academic Press
ISBN: 0128093943
Category : Science
Languages : en
Pages : 618
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Book Description
Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. - Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition - Contains new chapters that focus on subjects recent to the field - Includes well-illustrated material, with diagrams, charts, and tables - Contains compelling case studies and chapters written by world experts
Author:
Publisher:
ISBN:
Category : Industrial hygiene
Languages : en
Pages : 172
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Book Description
Author:
Publisher:
ISBN:
Category : Administrative law
Languages : en
Pages : 1040
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Book Description
Author: Stine Karen
Publisher: CRC Press
ISBN: 9780873716840
Category : Medical
Languages : en
Pages : 280
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Book Description
Written by two experienced toxicology lecturers, Principles of Toxicology is an easy-to-read, comprehensive textbook for a first course in toxicology at the undergraduate or graduate level - filling the acute need for a well-rounded introductory text. Students will no longer need to struggle with material that is too difficult or that has too narrow a toxicological focus. Principles of Toxicology covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and environmental and ecological. Within each chapter, the authors combine background material with new information in a manner that stresses principles and concepts. These principles are then illustrated with selected specific examples. This design helps students focus on understanding the subject rather than simply memorizing details. Your search for the perfect introductory toxicology text is over! Principles of Toxicology elegantly facilitates the teaching and learning of this challenging subject.
Author:
Publisher: Academic Press
ISBN: 0128137258
Category : Technology & Engineering
Languages : en
Pages : 1055
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Book Description
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field
