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Languages : en
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Author: Klaus Günther
Publisher:
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Category : Plasma (Ionized gases)
Languages : de
Pages : 130
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Languages : en
Pages :
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Languages : en
Pages : 0
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Author: National Library of Medicine (U.S.)
Publisher:
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Category : Medicine
Languages : en
Pages : 690
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First multi-year cumulation covers six years: 1965-70.
Author: Marija Pezer
Publisher: Springer Nature
ISBN: 3030769127
Category : Medical
Languages : en
Pages : 588
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This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author: R.M. Leuschner
Publisher: Birkhäuser
ISBN: 303487491X
Category : Science
Languages : en
Pages : 410
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Author: Rene Lontie
Publisher: CRC Press
ISBN: 1351079344
Category : Medical
Languages : en
Pages : 250
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These volumes of Copper Proteins and Copper Enzymes are intended to describe the contemporary spectroscopy and other biophysical chemistry now being applied to copper proteins in order to determine the structures of their active sites. Several chapters of the treatise describe the functional understanding which is emerging from the new work. The authors are all major contributors to research progress on copper proteins and the volumes will be found to be definitive and authoritative.
Author: Edward D. Levin
Publisher: Springer Science & Business Media
ISBN: 3764377720
Category : Medical
Languages : en
Pages : 284
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This book gathers cutting edge research on how transmitter interactions form the mechanistic bases for attention, learning and memory. The research provides a more accurate, though complex, picture of how the brain provides cognitive function, and offers new understanding about the mechanisms of cognitive dysfunction and novel avenues for therapeutic treatment. The contributors review their latest findings, and point out directions of advancement of the field of neurotransmitter interactions and cognitive function.
Author: G. Csaba
Publisher: Birkhäuser
ISBN: 3034892918
Category : Science
Languages : en
Pages : 193
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Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 762
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