Evolutionary Genomics and Proteomics

Evolutionary Genomics and Proteomics PDF Author: Mark D. Pagel
Publisher: Sinauer Associates, Incorporated
ISBN:
Category : Science
Languages : en
Pages : 372

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Book Description
Highlights new research on developments in the rapidly advancing areas of genomics and proteomics, with particular emphasis on placing these fields in an evolutionary context. Topics incude systems biology, the origin of genes and lateral gene transfer, gene regulation and gene dispensability, proteome complexity, genomic immune systems, sex-biased genomic expression, sex chromosome evolution, gene and protein network evolution, adaptive genome evolution, and human evolutional genomics.

Evolutionary Genomics and Proteomics

Evolutionary Genomics and Proteomics PDF Author: Mark D. Pagel
Publisher: Sinauer Associates, Incorporated
ISBN:
Category : Science
Languages : en
Pages : 372

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Book Description
Highlights new research on developments in the rapidly advancing areas of genomics and proteomics, with particular emphasis on placing these fields in an evolutionary context. Topics incude systems biology, the origin of genes and lateral gene transfer, gene regulation and gene dispensability, proteome complexity, genomic immune systems, sex-biased genomic expression, sex chromosome evolution, gene and protein network evolution, adaptive genome evolution, and human evolutional genomics.

Genomics and Proteomics

Genomics and Proteomics PDF Author: Devarajan Thangadurai
Publisher: CRC Press
ISBN: 149872311X
Category : Medical
Languages : en
Pages : 425

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Book Description
The book provides scope and knowledge on advanced techniques and its applications into the modern fields of biotechnology-genomics and proteomics. In this book, different genomics and proteomics technologies and principles are examined. The fundamental knowledge presented in this book opens up an entirely new way of approaching DNA chip technology,

Concepts of Biology

Concepts of Biology PDF Author: Samantha Fowler
Publisher:
ISBN: 9781680921021
Category :
Languages : en
Pages : 624

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Book Description
Concepts of Biology is designed for the introductory biology course for nonmajors taught at most two- and four-year colleges. The scope, sequence, and level of the program are designed to match typical course syllabi in the market. Concepts of Biology includes interesting applications, features a rich art program, and conveys the major themes of biology. The images in this textbook are grayscale.

Evolutionary Genomics and Systems Biology

Evolutionary Genomics and Systems Biology PDF Author: Gustavo Caetano-Anollés
Publisher: Wiley-Blackwell
ISBN: 0470570407
Category : Science
Languages : en
Pages : 330

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Book Description
A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.

Introduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers

Introduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers PDF Author: Robert B. Northrop
Publisher: CRC Press
ISBN: 1420061216
Category : Medical
Languages : en
Pages : 492

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Book Description
Illustrates the Complex Biochemical Relations that Permit Life to ExistIt can be argued that the dawn of the 21st century has emerged as the age focused on molecular biology, which includes all the regulatory mechanisms that make cellular biochemical reaction pathways stable and life possible. For biomedical engineers, this concept is essential to

Reaping the Benefits of Genomic and Proteomic Research

Reaping the Benefits of Genomic and Proteomic Research PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309100674
Category : Science
Languages : en
Pages : 189

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Book Description
The patenting and licensing of human genetic material and proteins represents an extension of intellectual property (IP) rights to naturally occurring biological material and scientific information, much of it well upstream of drugs and other disease therapies. This report concludes that IP restrictions rarely impose significant burdens on biomedical research, but there are reasons to be apprehensive about their future impact on scientific advances in this area. The report recommends 13 actions that policy-makers, courts, universities, and health and patent officials should take to prevent the increasingly complex web of IP protections from getting in the way of potential breakthroughs in genomic and proteomic research. It endorses the National Institutes of Health guidelines for technology licensing, data sharing, and research material exchanges and says that oversight of compliance should be strengthened. It recommends enactment of a statutory exception from infringement liability for research on a patented invention and raising the bar somewhat to qualify for a patent on upstream research discoveries in biotechnology. With respect to genetic diagnostic tests to detect patient mutations associated with certain diseases, the report urges patent holders to allow others to perform the tests for purposes of verifying the results.

Discovering Genomics, Proteomics, and Bioinformatics

Discovering Genomics, Proteomics, and Bioinformatics PDF Author: A. Malcolm Campbell
Publisher: Benjamin-Cummings Publishing Company
ISBN:
Category : Computers
Languages : en
Pages : 468

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Book Description
Discovering Genomics is the first genomics text that combines web activities and case studies with a problem-solving approach to teach upper-level undergraduates and first-year graduate students the fundamentals of genomic analysis. More of a workbook than a traditional text, Discovering Genomics, Second Edition allows students to work with real genomic data in solving problems and provides the user with an active learning experience. The companion website at www.aw-bc.com/geneticsplace is regularly updated to keep up with changes to online databases. The Second Edition has been thoroughly revised and updated to incorporate the latest scientific findings on popular topics such as disease-causing organisms and genetic defects. Case study chapters have been placed throughout the book to tie real-life scenarios into the concepts that follow. Two of the book's key pedagogical features, Discovery Questions and Math Minutes, have also been updated and expanded. The interactive companion website has been reprogrammed with JMOL, the latest 3-D software used to view DNA structures.

Sperm Biology

Sperm Biology PDF Author: Scott S. Pitnick
Publisher: Academic Press
ISBN: 0080919871
Category : Science
Languages : en
Pages : 683

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Book Description
Sperm Biology represents the first analysis of the evolutionary significance of sperm phenotypes and derived sperm traits and the possible selection pressures responsible for sperm-egg coevolution. An understanding of sperm evolution is fast developing and promises to shed light on many topics from basic reproductive biology to the evolutionary process itself as well as the sperm proteome, the sperm genome and the quantitative genetics of sperm. The Editors have identified 15 topics of current interest and biological significance to cover all aspects of this bizarre, fascinating and important subject. It comprises the most comprehensive and up-to-date review of the evolution of sperm and pointers for future research, written by experts in both sperm biology and evolutionary biology. The combination of evolution and sperm is a potent mix, and this is the definitive account. The first review survey of this emerging field Written by experts from a broad array of disciplines from the physiological and biomedical to the ecological and evolutionary Sheds light on the intricacies of reproduction and the coevolution of sperm, egg and reproductive behavior

Evolution of Translational Omics

Evolution of Translational Omics PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309224187
Category : Science
Languages : en
Pages : 354

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Book Description
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Evolutionary Genomics and Systems Biology

Evolutionary Genomics and Systems Biology PDF Author: Gustavo Caetano-Anoll¿s
Publisher: John Wiley & Sons
ISBN: 1118210719
Category : Science
Languages : en
Pages : 529

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Book Description
A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.