Author: Roger H. Sawyer
Publisher: Greenwood
ISBN:
Category : Science
Languages : en
Pages : 280
Book Description
Epithelial-mesenchymal Interactions in Development
Author: Roger H. Sawyer
Publisher: Greenwood
ISBN:
Category : Science
Languages : en
Pages : 280
Book Description
Publisher: Greenwood
ISBN:
Category : Science
Languages : en
Pages : 280
Book Description
Epithelial—Mesenchymal Interactions in Cancer
Author: Itzhak D. Goldberg
Publisher: Birkhäuser
ISBN: 3034890702
Category : Science
Languages : en
Pages : 304
Book Description
The contribution of epithelia-mesenchyme interaction to normal development (eg., tissue formation) and to neoplasia has become a subject of increasing interest to scientists because of recent progress in deciphering the molecular signals that mediate this interaction. Clearly, some of the same types of molecules (eg., growth factors and their receptors, proteolytic enzymes, cell adhesion molecules, and structural proteins of the extracellular matrix) mediate exchange of information between epithelia and mesenchyme during normal development and malignant growth. However, defects in the regulation of this exchange appear to contribute to malignancy by allowing growth promoting, invasogenic, and angiogenic factors to accumulate within the microenvironment of the tumor. For example, recent studies suggest that abnormal interactions between tumor epithelial cells and stromal mesenchymal cells contribute to the overproduction and accumulation of scatter factor (hepatocyte growth factor), an invasogenic and angiogenic cytokine, in certain types of tumor. The production and and activation of type IV collagenase, a matrix-degrading enzyme required for tumor cell invasion, appears to require intimate cooperation between tumor and stromal cells. The material contained in this volume highlights the state-of-the-art of knowledge of the molecular mechanisms by which epithelia and mesenchyme collaborate, and the abnormalities in these mechanisms that may lead to the development of cancer.
Publisher: Birkhäuser
ISBN: 3034890702
Category : Science
Languages : en
Pages : 304
Book Description
The contribution of epithelia-mesenchyme interaction to normal development (eg., tissue formation) and to neoplasia has become a subject of increasing interest to scientists because of recent progress in deciphering the molecular signals that mediate this interaction. Clearly, some of the same types of molecules (eg., growth factors and their receptors, proteolytic enzymes, cell adhesion molecules, and structural proteins of the extracellular matrix) mediate exchange of information between epithelia and mesenchyme during normal development and malignant growth. However, defects in the regulation of this exchange appear to contribute to malignancy by allowing growth promoting, invasogenic, and angiogenic factors to accumulate within the microenvironment of the tumor. For example, recent studies suggest that abnormal interactions between tumor epithelial cells and stromal mesenchymal cells contribute to the overproduction and accumulation of scatter factor (hepatocyte growth factor), an invasogenic and angiogenic cytokine, in certain types of tumor. The production and and activation of type IV collagenase, a matrix-degrading enzyme required for tumor cell invasion, appears to require intimate cooperation between tumor and stromal cells. The material contained in this volume highlights the state-of-the-art of knowledge of the molecular mechanisms by which epithelia and mesenchyme collaborate, and the abnormalities in these mechanisms that may lead to the development of cancer.
Epithelial-Mesenchymal Interactions
Author: Raul Fleischmajer
Publisher:
ISBN:
Category :
Languages : en
Pages : 326
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 326
Book Description
Epithelial-Mesenchymal Interactions in Cancer
Author: Itzhak D. Goldberg
Publisher:
ISBN: 9783034890717
Category :
Languages : en
Pages : 316
Book Description
Publisher:
ISBN: 9783034890717
Category :
Languages : en
Pages : 316
Book Description
Epithelial-Mesenchymal Interactions
Author: Raul Fleischmajer
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Epithelial Mesenchymal Interactions
Author: Thippeswamy Halappa
Publisher:
ISBN: 9783659854743
Category :
Languages : en
Pages : 116
Book Description
Publisher:
ISBN: 9783659854743
Category :
Languages : en
Pages : 116
Book Description
Morphogenesis of Skin
Author: Sengel
Publisher: CUP Archive
ISBN: 9780521206440
Category : Medical
Languages : en
Pages : 296
Book Description
Publisher: CUP Archive
ISBN: 9780521206440
Category : Medical
Languages : en
Pages : 296
Book Description
The Role of Epithelial-mesenchymal Interactions in Patterning the Developing Murine Lung
Author: Molly Weaver
Publisher:
ISBN:
Category : Cellular control mechanisms
Languages : en
Pages : 436
Book Description
Publisher:
ISBN:
Category : Cellular control mechanisms
Languages : en
Pages : 436
Book Description
Epithelial-mesanchymal Interactions
Author: Raul Fleischmajer (ed)
Publisher:
ISBN:
Category : Epithelium
Languages : en
Pages : 348
Book Description
Publisher:
ISBN:
Category : Epithelium
Languages : en
Pages : 348
Book Description
Epithelial-mesenchymal Interactions
Author: Annette M. Marme'
Publisher:
ISBN:
Category : Epithelium
Languages : en
Pages : 108
Book Description
Publisher:
ISBN:
Category : Epithelium
Languages : en
Pages : 108
Book Description