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Author: Stephanie Willerth
Publisher: Academic Press
ISBN: 0128113863
Category : Technology & Engineering
Languages : en
Pages : 224
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Book Description
Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications. Provides readers entering the field with a strong basis of neural tissue engineering processes and real-world applications Discusses the most current clinical trials and their importance of treating nervous system disorders Reviews the structure and immune response of the nervous system, including the brain, spinal cord and their present cells Offers a necessary overview of the natural and synthetic biomaterials used to engineer neural tissue
Author: Stephanie Willerth
Publisher: Academic Press
ISBN: 0128113863
Category : Technology & Engineering
Languages : en
Pages : 224
Get Book
Book Description
Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications. Provides readers entering the field with a strong basis of neural tissue engineering processes and real-world applications Discusses the most current clinical trials and their importance of treating nervous system disorders Reviews the structure and immune response of the nervous system, including the brain, spinal cord and their present cells Offers a necessary overview of the natural and synthetic biomaterials used to engineer neural tissue
Author: Stephanie Willerth
Publisher: Academic Press
ISBN: 9780128113851
Category : Technology & Engineering
Languages : en
Pages : 0
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Book Description
Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications.
Author: Lijie Grace Zhang
Publisher: Springer
ISBN: 3319314335
Category : Technology & Engineering
Languages : en
Pages : 311
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Book Description
This book covers the principles of advanced 3D fabrication techniques, stem cells and biomaterials for neural engineering. Renowned contributors cover topics such as neural tissue regeneration, peripheral and central nervous system repair, brain-machine interfaces and in vitro nervous system modeling. Within these areas, focus remains on exciting and emerging technologies such as highly developed neuroprostheses and the communication channels between the brain and prostheses, enabling technologies that are beneficial for development of therapeutic interventions, advanced fabrication techniques such as 3D bioprinting, photolithography, microfluidics, and subtractive fabrication, and the engineering of implantable neural grafts.There is a strong focus on stem cells and 3D bioprinting technologies throughout the book, including working with embryonic, fetal, neonatal, and adult stem cells and a variety of sophisticated 3D bioprinting methods for neural engineering applications. There is also a strong focus on biomaterials, including various conductive biomaterials and biomimetic nanomaterials such as carbon-based nanomaterials and engineered 3D nanofibrous scaffolds for neural tissue regeneration. Finally, two chapters on in vitro nervous system models are also included, which cover this topic in the context of studying physiology and pathology of the human nervous system, and for use in drug discovery research. This is an essential book for biomedical engineers, neuroscientists, neurophysiologists, and industry professionals.
Author: Song Li
Publisher: World Scientific
ISBN: 9814317055
Category : Science
Languages : en
Pages : 473
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Book Description
Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.
Author: Mirjana Pavlovic
Publisher: Springer Science & Business Media
ISBN: 1461455057
Category : Technology & Engineering
Languages : en
Pages : 159
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Book Description
Stem cells are the building blocks for all other cells in an organism. The human body has about 200 different types of cells and any of those cells can be produced by a stem cell. This fact emphasizes the significance of stem cells in transplantational medicine, regenerative therapy and bioengineering. Whether embryonic or adult, these cells can be used for the successful treatment of a wide range of diseases that were not treatable before, such as osteogenesis imperfecta in children, different forms of leukemias, acute myocardial infarction, some neural damages and diseases, etc. Bioengineering, e.g. successful manipulation of these cells with multipotential capacity of differentiation toward appropriate patterns and precise quantity, are the prerequisites for successful outcome and treatment. By combining in vivo and in vitro techniques, it is now possible to manage the wide spectrum of tissue damages and organ diseases. Although the stem-cell therapy is not a response to all the questions, it provides more and more answers every day. Stem Cells and Tissue Engineering is a concise review on the functional, phenotypic, regenerative, transplantational and curative aspects of a stem cell’s entity. It is critical and encouraging at the same time, providing truthful and appropriate samples from the practice and research that can lead toward optimal use of this immense source of adjuvant and curative therapy in human pathology. Written by a clinician and a researcher, who are currently teaching what they are doing, it is recommended as a teaching tool along with an original textbook.
Author: Li Song
Publisher: World Scientific
ISBN: 9813147768
Category : Science
Languages : en
Pages : 568
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Book Description
Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students. Contents: Tissue Engineering: From Basic Biology to Cell-Based Applications (R M Nerem)Recent Advances and Future Perspectives on Somatic Cell Reprogramming (K-Y Kim & I-H Park)Hematopoietic Stem Cells (J J Trowbridge)Mesenchymal Stem Cells for Tissue Regeneration (N F Huang & S Li)Delivery Vehicles for Deploying Mesenchymal Stem Cells in Tissue Repair (M S Friedman & J K Leach)Stem Cells for Cardiac Tissue Engineering (J L Young et al.)Cardiovascular System: Stem Cells in Tissue-Engineered Blood Vessels (R Sawh-Martinez et al.)Stem Cells for Vascular Regeneration: An Engineering Approach (L E Dickinson & S Gerecht)Stem Cells and Wound Repair (S H Ko et al.)Engineering Cartilage: From Materials to Small Molecules (J M Coburn & J H Elisseeff)Adult Stem Cells for Articular Cartilage Tissue Engineering (S Saha et al.)Stem Cells for Disc Repair (A A Allon et al.)Skeletal Tissue Engineering: Progress and Prospects (N J Panetta et al.)Clinical Applications of a Stem Cell Based Therapy for Oral Bone Reconstruction (B McAllister & K Haghighat)Therapeutic Strategies for Repairing the Injured Spinal Cord Using Stem Cells (M S Beattie & J C Bresnahan)Potential of Tissue Engineering and Neural Stem Cells in the Understanding and Treatment of Neurodegenerative Diseases (C Auclair-Daigle & F Berthod)High-Throughput Systems for Stem Cell Engineering (D A Brafman et al.)Microscale Technologies for Tissue Engineering and Stem Cell Differentiation (J W Nichol et al.)Quality Control of Autologous Cell- and Tissue-Based Therapies (N Dusserre et al.)Regulatory Challenges for Cell-Based Therapeutics (T McAllister et al.) Readership: Life science scientists; biomedical researchers; cell biologists; academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals. Keywords: Stem Cells;Tissue Engineering;Regenerative Medicine;Biotechnology;Cell EngineeringReview:0
Author: A. Wilkinson
Publisher: Springer Nature
ISBN: 3031025822
Category : Science
Languages : en
Pages : 112
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Book Description
Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks
Author:
Publisher: Academic Press
ISBN: 012410536X
Category : Science
Languages : en
Pages : 338
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Book Description
This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. This volume of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery
Author: Anwarul Hasan
Publisher: John Wiley & Sons
ISBN: 3527338632
Category : Science
Languages : en
Pages : 762
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Book Description
A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.
Author: A. E. Wilkinson
Publisher: Morgan & Claypool Publishers
ISBN: 1608457877
Category : Technology & Engineering
Languages : en
Pages : 122
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Book Description
Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks
