Endocytic Components: Identification and Characterization

Endocytic Components: Identification and Characterization PDF Author: J.J.M. Bergeron
Publisher: Springer Science & Business Media
ISBN: 1461530261
Category : Science
Languages : en
Pages : 269

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Book Description
In step with the rapid growth of research into the biochemical and functional characterization of the endosome, Volume 19 surveys the recent advances in the methodological aspects of this field. Coverage includes the use of free flow electrophoresis to define endosome subpopulations, the endosomal compartments in rat hepatocytes, the role of endosomes in transmembrane signalling, and six additional articles.

Biology of the Lysosome

Biology of the Lysosome PDF Author: John B. Lloyd
Publisher: Springer Science & Business Media
ISBN: 1461558336
Category : Science
Languages : en
Pages : 429

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Book Description
Volume 27 provides a comprehensive review of current knowledge of lysosome function in mammalian cells. The book's unique contribution is its series of chapters that offers unparalleled treatment of the metabolic activities of lysosomes.

Subcellular Biochemistry

Subcellular Biochemistry PDF Author: J. Robin Harris
Publisher: Springer Science & Business Media
ISBN: 1461303257
Category : Science
Languages : en
Pages : 446

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Book Description
In Volume 25, leading experts present studies on the value of increased ascorbic acid intake and explore its specific contributions to human and animal health.

Proteins: Structure, Function, and Engineering

Proteins: Structure, Function, and Engineering PDF Author: B.B. Biswas
Publisher: Springer Science & Business Media
ISBN: 1489917276
Category : Science
Languages : en
Pages : 451

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Book Description
Here, researchers review the latest breakthroughs in protein research. Their contributions explore emerging principles and techniques and survey important classes of proteins that will play key roles in the field's future. Articles examine the possibility of a Boltzman-like distribution in protein substructures, the new technique of Raman spectroscopy, and compact intermediate states of protein folding. This well-illustrated volume also features coverage of proteins that bind nucleic acids.

Mycoplasma Cell Membranes

Mycoplasma Cell Membranes PDF Author: Shlomo Rottem
Publisher: Springer Science & Business Media
ISBN: 1461529247
Category : Science
Languages : en
Pages : 326

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Book Description
The mycoplasmas, a trivial name used to denote organisms included in the class Mollicutes, are a group of prokaryotic organisms comprising more than 120 species distinguished from ordinary bacteria by their small size and the total lack of cell walls. The absence of a cell wall in mycoplasmas is a characteristic of outstanding importance to which the mycoplasmas owe many of their pecu liarities, for example, their morphological instability, osmotic sensitivity, unique ion pumping systems, resistance to antibiotics that interfere with cell wall bio synthesis, and susceptibility to lysis by detergents and alcohols. The fact that the mycoplasma cells contain only one membrane type, the plasma membrane, constitutes one of their most useful properties for membrane studies; once the membrane is isolated, it is uncontaminated with other mem brane types. Another advantage in using mycoplasmas as models for membrane studies stems from the fact that their membrane lipid composition can be altered in a controlled manner. This characteristic results from the partial or total inabili ty of the mycoplasmas to synthesize long-chain fatty acids and cholesterol, making mycoplasmas dependent on the supply of fatty acids from the growth medium. The ability to introduce controlled alterations in the fatty acid composi tion and cholesterol content of mycoplasma membranes has been utilized in studying the molecular organization and physical properties of biological mem branes.

Membrane Biogenesis

Membrane Biogenesis PDF Author: A.H. Maddy
Publisher: Springer Science & Business Media
ISBN: 1461524016
Category : Science
Languages : en
Pages : 424

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Book Description
Scientific reviews are now of two complementary types: short, very up-to-date articles, as are found in the Trends series, and the more traditional longer re views, which are more comprehensive but take longer to publish. The Subcellu lar Biochemistry series belongs to the latter category where a number of reviews on a broad topic are collected together in the one volume. It has been the aim of this volume to summarize the present state of knowledge of membrane assembly. It is appreciated that some relevant topics have not been included, and an editor's selection is restricted by the many calls on potential authors who are unable to meet all requests made to them. The absence of a discussion of the roles of lipids is," however, a reflection of the fact that a recent volume in this series, edited by Dr. H. 1. Hilderson, has been devoted to this subject (Vol. 16, Intracellular Transfer of Lipid Molecules), and readers are recommended to this source.

Handbook of Spectroscopy

Handbook of Spectroscopy PDF Author: G¿nter Gauglitz
Publisher: John Wiley & Sons
ISBN: 3527605029
Category : Science
Languages : en
Pages : 1168

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Book Description
This handbook provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that can be derived from spectra. The sequence of chapters covers a wide range of the electromagnetic spectrum, and the physical processes involved, from nuclear phenomena to molecular rotation processes. - A day-by-day laboratory guide: its design based on practical knowledge of spectroscopists at universities, industries and research institutes - A well-structured information source containing methods and applications sections framed by sections on general topics - Guides users to a decision about which spectroscopic method and which instrumentation will be the most appropriate to solve their own practical problem - Rapid access to essential information - Correct analysis of a huge number of measured spectra data and smart use of such information sources as databases and spectra libraries

myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction

myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction PDF Author: B.B. Biswas
Publisher: Springer Science & Business Media
ISBN: 1461303435
Category : Science
Languages : en
Pages : 433

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Book Description
`The heterogeneity of topics ... is very ambitious, and the result is, overall, successful because of the high quality of the individual contributions ... highly recommended.' -American Scientist, from a review of a previous volume Volume 26 examines the emerging areas of signal transduction based on myoinositol phosphates and Ca2+ while focusing on plant and animal responses. Chapters explore synthesis, separation, and identification of different inositol phosphates.

Physicochemical Methods in the Study of Biomembranes

Physicochemical Methods in the Study of Biomembranes PDF Author: Herwig J. Hilderson
Publisher: Springer Science & Business Media
ISBN: 1461518636
Category : Science
Languages : en
Pages : 524

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Book Description
In mammalian cells many physiological processes rely on the dynamics of the organization of lipids and proteins in biological membranes. The topics in this volume deal with physicochemical methods in the study of biomembranes. Some of them have a long and respectable history in the study of soluble proteins and have only recently been applied to the study of membranes. Some have tradi tionally been applied to studies of model systems of lipids of well-defined com position, as well as to intact membranes. Other methods, by their very nature, apply to organized bilayers comprised of both protein and lipid. Van Meer and van Genderen provide us with an introduction to the field (Chapter I). From their personal perspective regarding the distribution, trans port, and sorting of membrane lipids, they formulate a number of biologically relevant questions and show that the physicochemical methods described in this book may contribute in great measure to solving these issues. The methods of analytical ultracentrifugation have served faithfully for 60 years in the study of water-soluble proteins. The use of detergent extraction of membrane proteins, and the manipulation of density with H20/D20 mixtures, has extended this technique to the study of proteins, and in particular their interactions, from biological membranes. As described by Morris and Ralston in Chapter 2, this technique can be used to determine a number of important properties of proteins.

Cholesterol

Cholesterol PDF Author: Robert Bittman
Publisher: Springer Science & Business Media
ISBN: 1461559014
Category : Science
Languages : en
Pages : 567

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Book Description
Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholesterol in cancer, atherosclerosis, and diseases of the nervous system. The book's comprehensive coverage also includes the pathological consequences and potential therapies for various disease states, and the development of new anti-atherogenic drugs.