DNA-Encoded Libraries PDF Download
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Author: Andreas Brunschweiger
Publisher: Springer Nature
ISBN: 303118629X
Category : Science
Languages : en
Pages : 280
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Book Description
This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "disruptive" technology for drug discovery. The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as to graduate students and scholars who are interested in this rapidly improving technology.
Author: Herong Yang
Publisher: HerongYang.com
ISBN:
Category : Computers
Languages : en
Pages : 135
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Book Description
This book is a collection of tutorial notes and example codes written by the author while he was learning different data encoding algorithms. Topics include introduction of data encoding algorithms: Base32, Base64, UUEncode; Base64 Encoding Algorithm with W3C Implementation; Base64 Encoding tools and API in Java, Python, PHP and Perl; Base67URL Encoding to be URL and Filename safe; Base32 Encoding Algorithm with Java, PHP and C++ Implementations; URI/URL encoding with Java and PHP example programs; application/x-www-form-urlencoded encoding with Java and PHP example programs; UUEncode Encoding Algorithm with Sun Implementation. Updated in 2023 (Version v5.23) with minor changes. For latest updates and free sample chapters, visit https://www.herongyang.com/Encoding.
Author: Robert A. Goodnow, Jr.
Publisher: John Wiley & Sons
ISBN: 1118487680
Category : Science
Languages : en
Pages : 495
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Book Description
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Author: Andreas Brunschweiger
Publisher: Springer Nature
ISBN: 303118629X
Category : Science
Languages : en
Pages : 280
Get Book Here
Book Description
This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "disruptive" technology for drug discovery. The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as to graduate students and scholars who are interested in this rapidly improving technology.
Author: Nancy Ide
Publisher: Springer Science & Business Media
ISBN: 9780792336891
Category : Computers
Languages : en
Pages : 258
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Book Description
Charles F. Goldfarb Saratoga. California If asked for a sure recipe for chaos I would propose a I am delighted that my invention, the Standard project in which several thousand impassioned special Generalized Markup Language, was able to play a ists in scores of disciplines from a dozen or more role in the TEl's magnificent accomplishment, particu countries would be given five years to produce some larly because almost all of the original applications 1300 pages of guidelines for representing the informa of SGML were in the commercial and technological tion models of their specialties in a rigorous, machine realms. It is reasonable, of course, that organiza verifiable notation. Clearly, it would be sociologically tions with massive economic investments in new and and technologically impossible for such a group even changing information should want the benefits of infor to agree on the subject matter of such guidelines, let mation asset preservation and reuse that SGML offers. alone the coding details. But just as clearly as the It is gratifying that the TEl, representing the guardians bumblebee flies despite the laws of aerodynamics, the of humanity's oldest and most truly valuable informa Text Encoding Initiative has actually succeeded in such tion, chose SGML for those same benefits. an effort. The vaunted "information superhighway" would The TEl Guidelines are extraordinary.
Author: George M Church
Publisher: Basic Books
ISBN: 0465038654
Category : Science
Languages : en
Pages : 305
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Book Description
A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Author: Sareeta Amrute
Publisher: Duke University Press
ISBN: 0822374277
Category : Social Science
Languages : en
Pages : 244
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Book Description
In Encoding Race, Encoding Class Sareeta Amrute explores the work and private lives of highly skilled Indian IT coders in Berlin to reveal the oft-obscured realities of the embodied, raced, and classed nature of cognitive labor. In addition to conducting fieldwork and interviews in IT offices as well as analyzing political cartoons, advertisements, and reports on white-collar work, Amrute spent time with a core of twenty programmers before, during, and after their shifts. She shows how they occupy a contradictory position, as they are racialized in Germany as temporary and migrant grunt workers, yet their middle-class aspirations reflect efforts to build a new, global, and economically dominant India. The ways they accept and resist the premises and conditions of their work offer new potentials for alternative visions of living and working in neoliberal economies. Demonstrating how these coders' cognitive labor realigns and reimagines race and class, Amrute conceptualizes personhood and migration within global capitalism in new ways.
Author: Bill Stockting
Publisher: Routledge
ISBN: 0789030268
Category : Language Arts & Disciplines
Languages : en
Pages : 288
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Book Description
Encoding Across Frontiers is a careful selection of the finest presentations from the European Conference on Encoded Archival Description and Context (EAD and EAC) held in Paris, France in October 2004. International experts explore the history and practical use of EAD in Europe, the development and future of EAC, and a data format for information about archive holders, Encoded Archival Guide (EAG). Archivists will learn the latest in technology, practical applications, and international perspectives on how to transcend the printed word.
Author: Avinash Ramachandran
Publisher: Avinash Ramachandran
ISBN: 9780998045016
Category :
Languages : en
Pages : 228
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Book Description
Video coding is complex. YouTube and Netflix use it to deliver great video even at extremely low data rates. Have you ever wondered how they optimize video for low bandwidths? Do technical terms like 'rate distortion optimization', 'predictive coding' or 'adaptive quantization' overwhelm you? Decode To Encode is the only book that answers the hows and whys of elements in AVC (H.264), HEVC (H.265) and VP9. It provides video engineers and students all the compression fundamentals they need to solve problems, conduct research and serve their customers better. Coming from an experienced video codec engineer and product enthusiast, the book is written in a clear language with numerous examples.You will learn about: - digital video fundamentals and the evolution of codecs;- spatial and temporal aspects leveraged to achieve compression in block-based video architecture;- intra and inter coding, GOPs, block partitioning, prediction, transforms, quantization, CABAC, in-loop filtering, rate-distortion optimization and rate control;- bitrate modes, performance metrics and comparisons;- emerging topics like per-title encoding, AV1, 360 Video and VR, and encoding with ML.Why be left behind in today's evolving video landscape? Get the tools you need to understand technical specifications and design video algorithms. Learn the concepts in this book and become a compression expert today. Exude confidence as you walk into your next meeting or start a conversation about video compression
Author: Liss C. Werner
Publisher: Lulu.com
ISBN: 0976294141
Category : Architecture
Languages : en
Pages : 279
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Book Description
Author: Gustavo Sanchez
Publisher: Springer Nature
ISBN: 3030259277
Category : Technology & Engineering
Languages : en
Pages : 83
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Book Description
This book describes and analyzes in detail the encoding effort and the encoding tool usage applied to 3D-HEVC depth map coding. Based on the analyzed information, the authors introduce efficient algorithms for accelerating the available encoding tools. The contributions discussed in this book include four algorithms for reducing intra-frame encoding effort and three algorithms for reducing inter-frame encoding effort. The presented results demonstrate several levels of encoding effort reduction with different impacts in the encoding efficiency, surpassing state-of-the-art solutions by more than 50% the encoding effort with only 0.3% encoding efficiency loss.
