Therapeutic Strategies in Cancer Biology and Pathology PDF Download
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Author: Gajanan V. Sherbet
Publisher: Elsevier
ISBN: 9780128103425
Category : Medical
Languages : en
Pages : 312
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Book Description
Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. Identifies molecular targets and their accessibility for therapeutic interventionProvides information on biological features of tumor development and dissemination Background information provided for each topic
Author: Gajanan V. Sherbet
Publisher: Elsevier
ISBN: 9780128103425
Category : Medical
Languages : en
Pages : 312
Get Book Here
Book Description
Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. Identifies molecular targets and their accessibility for therapeutic interventionProvides information on biological features of tumor development and dissemination Background information provided for each topic
Author: Samuel Henry Dickson
Publisher:
ISBN:
Category :
Languages : en
Pages : 1030
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Book Description
Author: Aller Gustin Ellis
Publisher:
ISBN:
Category : Pathology
Languages : en
Pages : 658
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Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309174619
Category : Medical
Languages : en
Pages : 422
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Book Description
The most recent high-profile advocate for Americans with disabilities, actor Christopher Reeve, has highlighted for the public the economic and social costs of disability and the importance of rehabilitation. Enabling America is a major analysis of the field of rehabilitation science and engineering. The book explains how to achieve recognition for this evolving field of study, how to set priorities, and how to improve the organization and administration of the numerous federal research programs in this area. The committee introduces the "enabling-disability process" model, which enhances the concepts of disability and rehabilitation, and reviews what is known and what research priorities are emerging in the areas of: Pathology and impairment, including differences between children and adults. Functional limitationsâ€"in a person's ability to eat or walk, for example. Disability as the interaction between a person's pathologies, impairments, and functional limitations and the surrounding physical and social environments. This landmark volume will be of special interest to anyone involved in rehabilitation science and engineering: federal policymakers, rehabilitation practitioners and administrators, researchers, and advocates for persons with disabilities.
Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128132582
Category : Medical
Languages : en
Pages : 636
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Book Description
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Author: Matthew A. Wallig
Publisher: Academic Press
ISBN: 0080919324
Category : Medical
Languages : en
Pages : 714
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Book Description
Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
Author: Caleb Hillier Parry
Publisher:
ISBN:
Category : Pathology
Languages : en
Pages :
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Book Description
Author: Eve Caligor
Publisher: American Psychiatric Pub
ISBN: 1615371818
Category : Medical
Languages : en
Pages : 622
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Book Description
Deftly combining contemporary theory with clinical practice, Psychodynamic Therapy for Personality Pathology: Treating Self and Interpersonal Functioning is an invaluable resource for any clinician seeking a coherent model of personality functioning and pathology, classification, assessment, and treatment. This insightful guide introduces Transference-Focused Psychotherapy -- Extended (TFP-E), a specialized but accessible approach for any clinician interested in the skillful treatment of personality disorders. Compatible with the DSM-5 Section III Alternative Model for Personality Disorders -- and elaborating on that approach, this volume offers clinicians at all levels of experience an accessible framework to guide evaluation and treatment of personality disorders in a broad variety of clinical and research settings. In this book, readers will find: A coherent model of personality functioning and disorders based in psychodynamic object relations theory A clinically near approach to the classification of personality disorders, coupled with a comprehensive approach to assessment An integrated treatment model based on general clinical principles that apply across the spectrum of personality disorders An understanding of specific modifications of technique that tailor intervention to the individual patient's personality pathology Descriptions of specific psychodynamic techniques that can be exported to shorter-term treatments and acute clinical settings Patient assessment and basic psychodynamic techniques are described in up-to-date, jargon-free terms and richly supported by numerous clinical vignettes, as well as online videos demonstrating interventions. At the end of each chapter, readers will find a summary of key clinical concepts, making this book both a quick reference tool as well as a springboard for continued learning. Clinicians looking for an innovative, trustworthy guide to understanding and treating personality pathology that combines contemporary theory with clinical practice need look no further than Psychodynamic Therapy for Personality Pathology: Treating Self and Interpersonal Functioning.
Author: Karen A. Terio
Publisher: Academic Press
ISBN: 012809219X
Category : Science
Languages : en
Pages : 1424
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Book Description
Pathology of Wildlife and Zoo Animals is a comprehensive resource that covers the pathology of wildlife and zoo species, including a wide scope of animals, disease types and geographic regions. It is the definitive book for students, biologists, scientists, physicians, veterinary clinicians and pathologists working with non-domestic species in a variety of settings. General chapters include information on performing necropsies, proper techniques to meet the specialized needs of forensic cases, laboratory diagnostics, and an introduction into basic principles of comparative clinical pathology. The taxon-based chapters provide information about disease in related groups of animals and include descriptions of gross and histologic lesions, pathogenesis and diagnostics. For each group of animals, notable, unique gross and microscopic anatomical features are provided to further assist the reader in deciding whether differences from the domestic animal paradigm are "normal." Additional online content, which includes text, images, and whole scanned glass slides of selected conditions, expands the published material resulting in a comprehensive approach to the topic. - 2019 PROSE Awards - Winner: Category: Textbook/Biological and Life Sciences: Association of American Publishers - Presents a single resource for performing necropsies on a variety of taxa, including terrestrial and aquatic vertebrates and invertebrates - Describes notable, unique gross and microscopic anatomical variations among species/taxa to assist in understanding normal features, in particular those that can be mistaken as being abnormal - Provides consistent organization of chapters with descriptions of unique anatomic features, common non-infectious and infectious diseases following brief overviews of the taxonomic group - Contains full-color, high quality illustrations of diseases - Links to a large online library of scanned slides related to topics in the book that illustrate important histologic findings
Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128027878
Category : Medical
Languages : en
Pages : 805
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Book Description
As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. - Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease - Explains the practice of "molecular medicine and the translational aspects of molecular pathology - Teaches from the perspective of "integrative systems biology - Enhanced digital version included with purchase
