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Author: Dongqing Li
Publisher: Elsevier
ISBN: 0080530745
Category : Science
Languages : en
Pages : 653
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Book Description
A lab-on-a-chip device is a microscale laboratory on a credit-card sized glass or plastic chip with a network of microchannels, electrodes, sensors and electronic circuits. These labs on a chip can duplicate the specialized functions as performed by their room-sized counterparts, such as clinical diagnoses, PCR and electrophoretic separation. The advantages of these labs on a chip include significant reduction in the amounts of samples and reagents, very short reaction and analysis time, high throughput and portability. Generally, a lab-on-a-chip device must perform a number of microfluidic functions: pumping, mixing, thermal cycling/incubating, dispensing, and separating. Precise manipulation of these microfluidic processes is key to the operation and performance of labs on a chip. The objective of this book is to provide a fundamental understanding of the interfacial electrokinetic phenomena in several key microfluidic processes, and to show how these phenomena can be utilised to control the microfluidic processes. For this purpose, this book emphasises the theoretical modelling and the numerical simulation of these electrokinetic phenomena in microfluidics. However, experimental studies of the electrokinetic microfluidic processes are also highlighted in sufficient detail. The first book which systematically reviews electrokinetic microfluidics processes for lab-on-a chip applications Covers modelling and numerical simulation of the electrokinetic microfluidics processes Providing information on experimental studies and details of experimental techniques, which are essential for those who are new to this field
Author: Dongqing Li
Publisher: Elsevier
ISBN: 0080530745
Category : Science
Languages : en
Pages : 653
Get Book Here
Book Description
A lab-on-a-chip device is a microscale laboratory on a credit-card sized glass or plastic chip with a network of microchannels, electrodes, sensors and electronic circuits. These labs on a chip can duplicate the specialized functions as performed by their room-sized counterparts, such as clinical diagnoses, PCR and electrophoretic separation. The advantages of these labs on a chip include significant reduction in the amounts of samples and reagents, very short reaction and analysis time, high throughput and portability. Generally, a lab-on-a-chip device must perform a number of microfluidic functions: pumping, mixing, thermal cycling/incubating, dispensing, and separating. Precise manipulation of these microfluidic processes is key to the operation and performance of labs on a chip. The objective of this book is to provide a fundamental understanding of the interfacial electrokinetic phenomena in several key microfluidic processes, and to show how these phenomena can be utilised to control the microfluidic processes. For this purpose, this book emphasises the theoretical modelling and the numerical simulation of these electrokinetic phenomena in microfluidics. However, experimental studies of the electrokinetic microfluidic processes are also highlighted in sufficient detail. The first book which systematically reviews electrokinetic microfluidics processes for lab-on-a chip applications Covers modelling and numerical simulation of the electrokinetic microfluidics processes Providing information on experimental studies and details of experimental techniques, which are essential for those who are new to this field
Author: Dustin L. House
Publisher:
ISBN:
Category : Boundary element methods
Languages : en
Pages : 116
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Book Description
Author: Dongqing Li
Publisher: Springer Nature
ISBN: 3031161319
Category : Science
Languages : en
Pages : 288
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Book Description
This book reviews the latest advancement of microfluidics and nanofluidics with a focus on electrokinetic phenomena in microfluidics and nanofluidics. It provides fundamental understanding of several new interfacial electrokinetic phenomena in microfluidics and nanofluidics. Chapter 1 gives a brief review of the fundamentals of interfacial electrokinetics. Chapter 2 shows induced charge electrokinetic transport phenomena. Chapter 3 presents the new advancement in DC dielectrophoresis. Chapter 4 introduces a novel nanofabrication method and the systematic studies of electrokinetic nanofluidics. Chapter 5 presents electrokinetic phenomena associated with Janus particles and Janus droplets. Chapter 6 introduces a new direction of electrokinetic nanofluidics: nanofluidic iontronics. Chapter 7 discusses an important differential resistive pulse sensor in microfluidics and nanofluidics.
Author: Hsueh-Chia Chang
Publisher: Cambridge University Press
ISBN: 9780521860253
Category : Technology & Engineering
Languages : en
Pages : 526
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Book Description
Electrokinetics is currently the mechanism of choice for fluid actuation and bioparticle manipulation at microscale and nanoscale dimensions. There has recently been widespread interest in the use of AC electric fields, given the many advantages it offers over DC electrokinetics. Nevertheless, a fundamental understanding of the governing mechanisms underlying the complex and nonlinear physicochemical hydrodynamics associated with these systems is required before practical microfluidic and nanofluidic devices can be engineered. This text aims to provide a comprehensive treatise on both classical equilibrium electrokinetic phenomena as well as the more recent non-equilibrium phenomena associated with both DC and AC electrokinetics in the context of their application to the design of microfluidic and nanofluidic technology. In particular, Leslie Yeo and Hsueh-Chia Chang discuss the linear and nonlinear theories underlying electroosmosis, electrophoresis, and dielectrophoresis pertaining to electrolytes as well as dielectric systems. Interfacial electrokinetic phenomena such as electrospraying, electrospinning, and electrowetting are also discussed.
Author: Antonio Ramos
Publisher: Springer Science & Business Media
ISBN: 3709109000
Category : Technology & Engineering
Languages : en
Pages : 302
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Book Description
Among the most promising techniques to handle small objects at the micrometer scale are those that employ electrical forces, which have the advantages of voltage-based control and dominance over other forces. The book provides a state-of-the-art knowledge on both theoretical and applied aspects of the electrical manipulation of colloidal particles and fluids in microsystems and covers the following topics: dielectrophoresis, electrowetting, electrohydrodynamics in microsystems, and electrokinetics of fluids and particles. The book is addressed to doctoral students, young or senior researchers, chemical engineers and/or biotechnologists with an interest in microfluidics, lab-on-chip or MEMS.
Author: Xiangchun Xuan
Publisher: MDPI
ISBN: 3038424528
Category : Technology & Engineering
Languages : en
Pages : 203
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Book Description
This book is a printed edition of the Special Issue "Micro/Nano-Chip Electrokinetics" that was published in Micromachines
Author: Brian J. Kirby
Publisher: Cambridge University Press
ISBN: 1139489836
Category : Technology & Engineering
Languages : en
Pages : 536
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Book Description
This text focuses on the physics of fluid transport in micro- and nanofabricated liquid-phase systems, with consideration of gas bubbles, solid particles, and macromolecules. This text was designed with the goal of bringing together several areas that are often taught separately - namely, fluid mechanics, electrodynamics, and interfacial chemistry and electrochemistry - with a focused goal of preparing the modern microfluidics researcher to analyse and model continuum fluid mechanical systems encountered when working with micro- and nanofabricated devices. This text serves as a useful reference for practising researchers but is designed primarily for classroom instruction. Worked sample problems are included throughout to assist the student, and exercises at the end of each chapter help facilitate class learning.
Author: Jacob H. Masliyah
Publisher: John Wiley & Sons
ISBN: 0471799734
Category : Science
Languages : en
Pages : 733
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Book Description
A new, definitive perspective of electrokinetic and colloid transport processes Responding to renewed interest in the subject of electrokinetics, Electrokinetic and Colloid Transport Phenomena is a timely overview of the latest research and applications in this field for both the beginner and the professional. An outgrowth of an earlier text (by coauthor Jacob Masliyah), this self-contained reference provides an up-to-date summary of the literature on electrokinetic and colloid transport phenomena as well as direct pedagogical insight into the development of the subject over the past several decades. A distinct departure from standard colloid science monographs, Electrokinetic and Colloid Transport Phenomena presents the most salient features of the theory in a simple and direct manner, allowing the book to serve as a stepping-stone for further learning and study. In addition, the book uniquely discusses numerical simulation of electrokinetic problems and demonstrates the use of commercial finite element software for solving these multiphysics problems. Among the topics covered are: * Mathematical preliminaries * Colloidal systems * Electrostatics and application of electrostatics * Electric double layer * Electroosmosis and streaming potential * Electrophoresis and sedimentation potential * London-Van der Waals forces and the DLVO theory * Coagulation and colloid deposition * Numerical simulation of electrokinetic phenomena * Applications of electrokinetic phenomena Because this thorough reference does not require advanced mathematical knowledge, it enables a graduate or a senior undergraduate student approaching the subject for the first time to easily interpret the theories. On the other hand, the application of relevant mathematical principles and the worked examples are extremely useful to established researchers and professionals involved in a wide range of areas, including electroosmosis, streaming potential, electrophoretic separations, industrial practices involving colloids and complex fluids, environmental remediation, suspensions, and microfluidic systems.
Author: Mehmet Basar Karacor
Publisher:
ISBN:
Category : Electrokinetics
Languages : en
Pages : 81
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Book Description
Electroosmotic flow control in microfluidic devices is an important and challenging problem, as electroosmosis directly influences separation efficiencies in lab-on-chip applications. In this study, a non-mechanical passive flow directing method is presented for electrokinetically driven flow. Due to the high surface-area-to-volume (SA/V) ratio, surface properties dominate the flow in microfluidic channels. For electrokinetically driven flows, the main surface property affecting electroosmotic flows is the surface [zeta] potential, which is related to the effective surface charge density. By changing the effective surface charge density, the electroosmotic flow rates of charged species can be controlled in microfluidic channels. In this work, to change the effective surface charge density, surfaces were chemically modified with --Br, --NH2 and --CH3 functional groups by "click" chemistry. Since these functional surface layers are integrated within model glass microfluidic devices prepared by standard microfabrication procedures, the first step was to investigate the stability of the adherent surface layers to a variety of microfabrication conditions. A model "Y" shaped glass microfluidic device was developed. One leg of this model microfluidic device was selectively chemically modified to alter the [zeta] potential and thereby increase or decrease the electroosmotic flow with respect to rest of the device. Electroosmotic flow is visualized by using marker dyes under a fluorescent microscope. In addition, experiments were validated by using the CFD code in COMSOL. The experiments concluded that the surface layers are stable to a variety of conditions including a wide pH range (pH 3 -- pH 11), solvent exposure, acid and base exposure, and UV light. Extreme conditions such as a piranha solution or oxidative plasma degrade the surface layers. Electrokinetic flow experiments show that depending on the charge of a species the electroosmotic flow is preferentially directed as a function of the [zeta] potential in the microfluidic channels.
Author: Tai-Ran Hsu
Publisher: IET
ISBN: 9780863413353
Category : Technology & Engineering
Languages : en
Pages : 310
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Book Description
This book covers the entire spectrum of assembly, packaging and testing of MEMs (microelectro-mechanical systems) and microsystems, from essential enabling technologies to applications in key industries of life sciences, telecommunications and aerospace engineering.
