Cell Biology of Extracellular Matrix PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Cell Biology of Extracellular Matrix PDF full book. Access full book title Cell Biology of Extracellular Matrix by E.D. Hay. Download full books in PDF and EPUB format.
Author: E.D. Hay
Publisher: Springer Science & Business Media
ISBN: 1461537703
Category : Science
Languages : en
Pages : 478
Get Book Here
Book Description
In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Author: E.D. Hay
Publisher: Springer Science & Business Media
ISBN: 1461537703
Category : Science
Languages : en
Pages : 478
Get Book Here
Book Description
In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Author: Robert Schleip
Publisher: Elsevier Health Sciences
ISBN: 0702052280
Category : Medical
Languages : en
Pages : 566
Get Book Here
Book Description
This book is the product of an important collaboration between clinicians of the manual therapies and scientists in several disciplines that grew out of the three recent International Fascia Research Congresses (Boston, Amsterdam, and Vancouver). The book editors, Thomas Findley MD PhD, Robert Schleip PhD, Peter Huijing PhD and Leon Chaitow DO, were major organizers of these congresses and used their extensive experience to select chapters and contributors for this book. This volume therefore brings together contributors from diverse backgrounds who share the desire to bridge the gap between theory and practice in our current knowledge of the fascia and goes beyond the 2007, 2009 and 2012 congresses to define the state-of-the-art, from both the clinical and scientific perspective. Prepared by over 100 specialists and researchers from throughout the world, Fascia: The Tensional Network of the Human Body will be ideal for all professionals who have an interest in fascia and human movement - physiotherapists, osteopathic physicians, osteopaths, chiropractors, structural integration practitioners, manual therapists, massage therapists, acupuncturists, yoga or Pilates instructors, exercise scientists and personal trainers - as well as physicians involved with musculoskeletal medicine, pain management and rehabilitation, and basic scientists working in the field. - Reflects the efforts of almost 100 scientists and clinicians from throughout the world - Offers comprehensive coverage ranging from anatomy and physiology, clinical conditions and associated therapies, to recently developed research techniques - Explores the role of fascia as a bodywide communication system - Presents the latest information available on myofascial force transmission which helps establish a scientific basis for given clinical experiences - Explores the importance of fascia as a sensory organ - for example, its important proprioceptive and nociceptive functions which have implications for the generation of low back pain - Describes new imaging methods which confirm the connectivity of organs and tissues - Designed to organize relevant information for professionals involved in the therapeutic manipulation of the body's connective tissue matrix (fascia) as well as for scientists involved in basic science research - Reflects the increasing need for information about the properties of fascia, particularly for osteopaths, massage therapists, physiotherapists and other complementary health care professionals - Offers new insights on the fascial related foundations of Traditional Chinese Medicine Meridians and the fascial effects of acupuncture
Author: L. Sandberg
Publisher: Springer Science & Business Media
ISBN: 1468490931
Category : Science
Languages : en
Pages : 762
Get Book Here
Book Description
Although elastin was first identified and purifled in 1840, relatively few, major advances to determine its structure and function occurred between then and 1970. This was pointed out by Carl Franzblau in his recent review (1). This sad state of affairs does not detract, however, from the importance of contributions made during the last 50 years; many of these are referred to in the various chapters that comprise this monograph. I would be remiss not to emphasize the pioneering work of S. M. Partridge, who, in 1955, reported on a technique to obtain virtually pure elastin. It was, indeed, a privilege to have the participation of Dr. Partridge in the First International Conference on Elastin, the proceedings of which constitute this volume. In 1974, the Division of Lung Diseases of the National Heart, Lung, and Blood Institute initiated a targeted research program on "Isolation and Purification of Lung Elastin". It was an asset to the program that it attracted eminent scientists who, in effect, stimulated a new wave of interest and activity in this neglected area of research. This resurgence of interest may have been due to the challenge of working with a tissue that presented difficulties which had in the past discour aged investigators. It soon became apparent that the research program initiated by the Division of Lung Diseases was attracting much interest and that many significant contributions would result from it.
Author: Morten Karsdal
Publisher: Academic Press
ISBN: 0128098996
Category : Science
Languages : en
Pages : 274
Get Book Here
Book Description
Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease. - Provides a comprehensive introduction to collagen and structural proteins - Provides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation - Includes a chapter dedicated to the biomarkers of structural proteins - Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states
Author: Jouni Uitto
Publisher: CRC Press
ISBN: 1000447227
Category : Science
Languages : en
Pages : 576
Get Book Here
Book Description
This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.
Author: Peter D. Yurchenco
Publisher: Academic Press
ISBN: 1483289427
Category : Science
Languages : en
Pages : 483
Get Book Here
Book Description
The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. - Addresses assembly of most of the known classes of extracellular matrix macromolecules - Discusses higher order structures produced by ECM - Gives important concepts in ECM and cell-matrix interactions, Protein structure and protein-protein interactions, Development and tissue remodeling
Author: Jaroslava Halper
Publisher: Springer Science & Business Media
ISBN: 9400778937
Category : Medical
Languages : en
Pages : 246
Get Book Here
Book Description
This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and to the actual or potential treatment of them. Progress in Heritable Soft Connective Tissue Diseases features very prominent physicians and scientists as contributors who bring their most recent discoveries to the benefit of readers. Their expertise will help clinicians with proper diagnosis of sometimes elusive and uncommon heritable diseases of soft connective tissues. This book also offers an update on the pathophysiology of these diseases, including an emphasis on unifying aspects such as connections between embryonic development of the different types of connective tissues and systems, and the role of TGF-beta in development and physiology of soft tissues. This new set of data explains, at least in part, why many of these disorders are interconnected, though the primary pathophysiological events, such as gene mutations, may be different for each disorder.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Richard L. Kradin
Publisher: Academic Press
ISBN: 0128014466
Category : Science
Languages : en
Pages : 358
Get Book Here
Book Description
Understanding Pulmonary Pathology: Applying Pathological Findings in Therapeutic Decision Making provides a much needed reference tool for pathologists, practicing pulmonologists, and pulmonologist researchers. The unique approach to pulmonary pathology combines the multi-perspective views of the author who was trained formally as both a pulmonologist and as a pathologist. The book addresses what is often lost in translation when conveying the experience of pulmonary pathology in practicing pulmonary medicine. This important tool conveys detailed information concerning the anatomic basis of disease to those oriented towards thinking about diseases physiologically, providing the opportunity for optimal diagnosis, treatment of patients, and advancement of research. - Bridges the knowledge gap between the pathologist, practicing pulmonologist, and pulmonologist researcher - Contains a one-of-a-kind index that lists pathological terms and describes how they relate to disease diagnosis and impact pulmonary function - Includes the current international guidelines with a critical analysis of how pathology is reflected within them - Provides full-color, microscopic pictures on referenced topics
Author: Radivoj V. Krstic
Publisher: Springer Science & Business Media
ISBN: 3642704204
Category : Medical
Languages : en
Pages : 689
Get Book Here
Book Description
With a Foreword by Reiter R.J. Translated by Forster, S.
