Economic Evaluation in Clinical Trials

Economic Evaluation in Clinical Trials PDF Author: Henry A. Glick
Publisher: OUP Oxford
ISBN: 0191508063
Category : Medical
Languages : en
Pages : 274

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Book Description
It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also vital for addressing the requirements of regulatory bodies. Economic Evaluation in Clinical Trials provides practical advice on how to conduct cost-effectiveness analyses in controlled trials of medical therapies. This new edition has been extensively rewritten and revised; topics discussed range from design issues such as the types of services that should be measured and price weights, to assessment of quality-adjusted life years. Illustrative materials, case histories and worked examples are included to encourage the reader to apply the methods discussed. These exercises are supported with datasets, programmes and solutions made available online.

Economic Evaluation in Clinical Trials

Economic Evaluation in Clinical Trials PDF Author: Henry A. Glick
Publisher: OUP Oxford
ISBN: 0191508063
Category : Medical
Languages : en
Pages : 274

Get Book Here

Book Description
It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also vital for addressing the requirements of regulatory bodies. Economic Evaluation in Clinical Trials provides practical advice on how to conduct cost-effectiveness analyses in controlled trials of medical therapies. This new edition has been extensively rewritten and revised; topics discussed range from design issues such as the types of services that should be measured and price weights, to assessment of quality-adjusted life years. Illustrative materials, case histories and worked examples are included to encourage the reader to apply the methods discussed. These exercises are supported with datasets, programmes and solutions made available online.

Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement

Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement PDF Author: Iftekhar Khan
Publisher: CRC Press
ISBN: 1466505486
Category : Mathematics
Languages : en
Pages : 332

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Book Description
Economic evaluation has become an essential component of clinical trial design to show that new treatments and technologies offer value to payers in various healthcare systems. Although many books exist that address the theoretical or practical aspects of cost-effectiveness analysis, this book differentiates itself from the competition by detailing

Decision Modelling for Health Economic Evaluation

Decision Modelling for Health Economic Evaluation PDF Author: Andrew Briggs
Publisher: OUP Oxford
ISBN: 0191004952
Category : Medical
Languages : en
Pages : 269

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Book Description
In financially constrained health systems across the world, increasing emphasis is being placed on the ability to demonstrate that health care interventions are not only effective, but also cost-effective. This book deals with decision modelling techniques that can be used to estimate the value for money of various interventions including medical devices, surgical procedures, diagnostic technologies, and pharmaceuticals. Particular emphasis is placed on the importance of the appropriate representation of uncertainty in the evaluative process and the implication this uncertainty has for decision making and the need for future research. This highly practical guide takes the reader through the key principles and approaches of modelling techniques. It begins with the basics of constructing different forms of the model, the population of the model with input parameter estimates, analysis of the results, and progression to the holistic view of models as a valuable tool for informing future research exercises. Case studies and exercises are supported with online templates and solutions. This book will help analysts understand the contribution of decision-analytic modelling to the evaluation of health care programmes. ABOUT THE SERIES: Economic evaluation of health interventions is a growing specialist field, and this series of practical handbooks will tackle, in-depth, topics superficially addressed in more general health economics books. Each volume will include illustrative material, case histories and worked examples to encourage the reader to apply the methods discussed, with supporting material provided online. This series is aimed at health economists in academia, the pharmaceutical industry and the health sector, those on advanced health economics courses, and health researchers in associated fields.

Applied Methods of Cost-effectiveness Analysis in Healthcare

Applied Methods of Cost-effectiveness Analysis in Healthcare PDF Author: Alastair Gray
Publisher: Oxford University Press, USA
ISBN: 0199227284
Category : Business & Economics
Languages : en
Pages : 326

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Book Description
This book provides the reader with a comprehensive set of instructions and examples of how to perform an economic evaluation of a health intervention, focusing solely on cost-effectiveness analysis in healthcare.

Measuring and Valuing Health Benefits for Economic Evaluation

Measuring and Valuing Health Benefits for Economic Evaluation PDF Author: John Brazier
Publisher: Oxford University Press
ISBN: 0198725922
Category : Business & Economics
Languages : en
Pages : 373

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Book Description
There are not enough resources in health care systems around the world to fund all technically feasible and potentially beneficial health care interventions. Difficult choices have to be made, and economic evaluation offers a systematic and transparent process for informing such choices. A key component of economic evaluation is how to value the benefits of health care in a way that permits comparison between health care interventions, such as through costs per quality-adjusted life years (QALY). Measuring and Valuing Health Benefits for Economic Evaluation examines the measurement and valuation of health benefits, reviews the explosion of theoretical and empirical work in the field, and explores an area of research that continues to be a major source of debate. It addresses the key questions in the field including: the definition of health, the techniques of valuation, who should provide the values, techniques for modelling health state values, the appropriateness of tools in children and vulnerable groups, cross cultural issues, and the problem of choosing the right instrument. This new edition contains updated empirical examples and practical applications, which help to clarify the readers understanding of real world contexts. It features a glossary containing the common terms used by practitioners, and has been updated to cover new measures of health and wellbeing, such as ICECAP, ASCOT and AQOL. It takes into account new research into the social weighting of a QALY, the rising use of ordinal valuation techniques, use of the internet to collect data, and the use of health state utility values in cost effectiveness models. This is an ideal resource for anyone wishing to gain a specialised understanding of health benefit measurement in economic evaluation, especially those working in the fields of health economics, public sector economics, pharmacoeconomics, health services research, public health, and quality of life research.

Applied Health Economics for Public Health Practice and Research

Applied Health Economics for Public Health Practice and Research PDF Author: Rhiannon Tudor Edwards
Publisher: Oxford University Press
ISBN: 0191057231
Category : Medical
Languages : en
Pages : 351

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Book Description
In today's world of scare resources, determining the optimal allocation of funds to preventive health care interventions (PHIs) is a challenge. The upfront investments needed must be viewed as long term projects, the benefits of which we will experience in the future. The long term positive change to PHIs from economic investment can be seen across multiple sectors such as health care, education, employment and beyond. Applied Health Economics for Public Health Practice and Research is the fifth in the series of Handbooks in Health Economic Evaluation. It presents new research on health economics methodology and application to the evaluation of public health interventions. Looking at traditional as well as novel methods of economic evaluation, the book covers the history of economics of public health and the economic rationale for government investment in prevention. In addition, it looks at principles of health economics, evidence synthesis, key methods of economic evaluation with accompanying case studies, and much more. Looking to the future, Applied Health Economics for Public Health Practice and Research presents priorities for research in the field of public health economics. It acknowledges the role played by natural environment in promoting better health, and the place of genetics, environment and socioeconomic status in determining population health. Ideal for health economists, public health researchers, local government workers, health care professionals, and those responsible for health policy development. Applied Health Economics for Public Health Practice and Research is an important contribution to the economic discussion of public health and resource allocation.

Economic Evaluation in Genomic Medicine

Economic Evaluation in Genomic Medicine PDF Author: Vasilios Fragoulakis
Publisher: Academic Press
ISBN: 0128016116
Category : Science
Languages : en
Pages : 174

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Book Description
Economic Evaluation in Genomic Medicine introduces health economics and economic evaluation to genomic clinicians and researchers, while also introducing the topic to health economists. Each chapter includes an executive summary, questions, and case studies, along with supplementary online materials, including process guides, maps, flow charts, diagrams, and economic evaluation spreadsheets to enhance the learning process. The text can easily be used as course material for related graduate and undergraduate courses, providing a succinct overview of the existing, state-of-the-art application of economic evaluation to genomic healthcare and precision medicine. - Interrelates economic evaluation and genomic medicine - Instructs healthcare professionals and bioscientists about economic evaluation in genomic medicine - Teaches health economists about application of economic evaluation in genomic medicine - Introduces health economics and economic evaluation to clinicians and researchers involved in genomics - Includes process guides, maps, flow charts and diagrams

Distributional Cost-Effectiveness Analysis

Distributional Cost-Effectiveness Analysis PDF Author: Richard Cookson
Publisher:
ISBN: 0198838190
Category : Business & Economics
Languages : en
Pages : 385

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Book Description
Distributional cost-effectiveness analysis aims to help healthcare and public health organizations make fairer decisions with better outcomes. It can provide information about equity in the distribution of costs and effects - who gains, who loses, and by how much - and the trade-offs that sometimes occur between equity and efficiency. This is a practical guide to methods for quantifying the equity impacts of health programmes in high, middle, and low-income countries. The methods can be tailored to analyse different equity concerns in different decision making contexts. The handbook provides both hands-on training for postgraduate students and analysts and an accessible guide for academics, practitioners, managers, policymakers, and stakeholders. Part I is an introduction and overview for research commissioners, users, and producers. Parts II and III provide step-by-step guidance on how to simulate and evaluate distributions, with accompanying spreadsheet training exercises. Part IV concludes with discussions about how to handle uncertainty about facts and disagreement about values, and the future challenges facing this growing field. Book jacket.

Economic Analysis in Healthcare

Economic Analysis in Healthcare PDF Author: Stephen Morris
Publisher: John Wiley & Sons
ISBN: 1119951496
Category : Medical
Languages : en
Pages : 402

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Book Description
Economic Analysis in Health Care, Second Edition is intended as a core textbook for advanced undergraduate and postgraduate students of health economics. The authors provide comprehensive coverage of the field of economics in health care and the evaluation of health care technologies. This new edition has been fully updated with up-to-date case studies from the UK, Europe and the Rest of the World. It includes a new chapter on health care labour markets and contains new material integrated throughout the text on the economics of public health. Adopts an international perspective towards topics in health economics Creates a useful balance of theoretical treatment and practical application throughout the book Focuses on both market-related and economic evaluation aspects of health economics.

Statistical Aspects Of The Design And Analysis Of Clinical Trials (Revised Edition)

Statistical Aspects Of The Design And Analysis Of Clinical Trials (Revised Edition) PDF Author: Brian S Everitt
Publisher: World Scientific
ISBN: 1783260777
Category : Medical
Languages : en
Pages : 338

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Book Description
Fully updated, this revised edition describes the statistical aspects of both the design and analysis of trials, with particular emphasis on the more recent methods of analysis.About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. This book provides a useful guide to medical statisticians and others faced with the often difficult problems of designing and analysing clinical trials./a