Evolution by Gene Duplication PDF Download
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Author: Susumu Ohno
Publisher: Springer Science & Business Media
ISBN: 364286659X
Category : Medical
Languages : en
Pages : 171
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Book Description
It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.
Author: Susumu Ohno
Publisher: Springer Science & Business Media
ISBN: 364286659X
Category : Medical
Languages : en
Pages : 171
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Book Description
It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.
Author: Eric Lofholm
Publisher:
ISBN: 9780989894227
Category :
Languages : en
Pages : 42
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Book Description
Author: Felix Friedberg
Publisher: BoD – Books on Demand
ISBN: 953307387X
Category : Medical
Languages : en
Pages : 416
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Book Description
The book Gene Duplication consists of 21 chapters divided in 3 parts: General Aspects, A Look at Some Gene Families and Examining Bundles of Genes. The importance of the study of Gene Duplication stems from the realization that the dynamic process of duplication is the "sine qua non" underlying the evolution of all living matter. Genes may be altered before or after the duplication process thereby undergoing neofunctionalization, thus creating in time new organisms which populate the Earth.
Author: Charles William Prentiss
Publisher:
ISBN:
Category : Nereidae
Languages : en
Pages : 24
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Book Description
Author: Katharina Dittmar
Publisher: John Wiley & Sons
ISBN: 1118148096
Category : Science
Languages : en
Pages : 350
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Book Description
Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity. Key Features: Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system) A complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways Taps the significant increase in multi-gene family data that has resulted from comparative genomics Comprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.
Author: Woody Leonhard
Publisher: John Wiley & Sons
ISBN: 1118052099
Category : Computers
Languages : en
Pages : 378
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Book Description
If you work in an office, you probably don’t lose much sleep worrying about whether your files are safe if your PC melts down. Company IT departments handle those things for business networks. But how about all those precious photos, address lists, the family genealogy, and everything else that lives on your home network? Windows Home Server can save the day if one of your personal PCs hiccups, and Windows Home Server For Dummies serves up all the stuff you need to know to put it to work. Forget everything you’ve heard about previous versions of Windows Server; this all-new variation has been designed for people who don’t wear white lab coats or pocket protectors. Woody Leonhard has tested it and it passed with flying colors. If you have a home or small business network, this book shows you how Windows Home Server helps you Share files among all the PCs in your home Access your files from anywhere Make regular backups automatically Store files securely Play music, TV shows, or movies on your Xbox Share multimedia across your network Keep your virus protection and system upgrades up to date Get regular reports on the overall health of your network Windows Home Server For Dummies provides sage advice on choosing a version of Windows Home Server, installing it, setting up users and passwords, using remote access, scheduling automatic scans and backups, and having fun with multimedia. Trust Woody— you’ll sleep better.
Author: Phillip Slater
Publisher: Industrial Press Inc.
ISBN: 9780831134013
Category : Business & Economics
Languages : en
Pages : 276
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Book Description
Engineers and reliability professionals are increasingly being held accountable for materials and spare parts inventory management and in response they need to gain a better understanding of materials and spare parts inventory management principles and practices. This practical book delivers just that. This new edition will help you get the right parts, in the right place, at the right time, for the right reason. Fully revised, it provides specific coverage of the issues faced in, and requirements for, managing engineering materials and spare parts and what to do to improve your results. It includes 29 exclusive examples and real life case studies to demonstrate the application of the concepts and ideas so that you will easy and quickly understand how to implement them. What's more it will show you: What to do to truly optimize your inventory holdings, Why inventory levels are almost always too high, How to identifying the factors that have greatest impact on your inventory levels, When to apply the 7 Actions for Inventory Reduction, Where to focus your efforts for greatest effect, and Who to involve in taking action. The concepts, ideas, tools, and processes in this book have helped many companies achieve and sustain results that other inventory tools and approaches just could not match. And it is sure to help you achieve true inventory optimization as well! Features The second edition includes... A new chapter on The Mechanics of Inventory Management, a pragmatic review of the management of inventory including... Introducing the Materials and Inventory Management Cycle, Comparing theoretical and actual inventory outcomes, Discussion on normal and Poisson distribution models, How to determine the re order point, How to determine the re order quantity, and Commentary on Monte Carlo simulation. An expanded chapter on the financial impact of inventory, including a discussion of the key reports that need to be understood. Chapters on the influence of policies, procedures, and people. Additional discussion on issues faced and how to address them. An expansion of the central process discussed in the first edition to a more comprehensive review process...Inventory Process(TM) Optimization. An expanded section on executing an inventory review program. A closing 'where to from here' chapter. 57 figures and diagrams - 30 of them new and the others all revised and updated and six new tables (with 8 in total). Eight new checklists - specifically included as a new tool for the reader and is the result of direct reader requests. An expanded glossary.
Author: Benjamin Pierce
Publisher: Macmillan
ISBN: 9780716775492
Category : Science
Languages : en
Pages : 836
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Book Description
Based on the author's more than twenty years of teaching experience, Genetics: A Conceptual Approach offers a fresh new way of introducing the major concepts and mechanics of genetics, focusing students on the big picture without overwhelming them with detail.
Author: George W. Holcomb
Publisher: Elsevier Health Sciences
ISBN: 0323187366
Category : Medical
Languages : en
Pages : 1191
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Book Description
Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today’s best practices. Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout. Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more. Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.
Author: Russ B Altman
Publisher: World Scientific
ISBN: 9814469262
Category : Science
Languages : en
Pages : 567
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Book Description
The Pacific Symposium on Biocomputing (PSB) 2009 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2009 will be held on January 5-9, 2009 in Kamuela, Hawaii. Tutorials will be offered prior to the start of the conference.PSB 2009 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
