Dr. Folkman's War

Dr. Folkman's War PDF Author: Robert Cooke
Publisher:
ISBN: 9780812974843
Category : Cancer
Languages : en
Pages : 0

Get Book Here

Book Description
In 1961, twenty-eight-year-old Dr. Judah Folkman saw something while doing medical research in a United States navy lab that gave him the first glimmering of a wild, inspired hunch. What if cancerous tumors, in order to expand, needed to trigger the growth of new blood vessels to feed themselves? And if that was true, what if a way could be found to stop that growth? Could cancers be starved to death? Dr. Folkman had ample reason to be self confident — second in his class at Harvard Medical School, he was already considered one of the most promising doctors of his generation. But even he never guessed that his idea would eventually grow into a multibillion-dollar industry that is now racing through human trials with drugs that show unparalleled promise of being able to control cancer, as well as other deadly diseases. For the creation of this book, Dr. Judah Folkman cooperated fully and exclusively with acclaimed science writer Robert Cooke. He granted Cooke unlimited interviews, showed him diaries and personal papers, and threw open the doors of his lab. The result is an astonishingly rich and candid chronicle of one of the most significant medical discoveries of our time and of the man whose vision and persistence almost single-handedly has made it possible. Dr. Folkman's radical new way of thinking about cancer was once considered preposterous. So little was known about how cancer spreads and how blood vessels grow that he wasn't even taken seriously enough to be considered a heretic. Other doctors shook their heads at the waste of a great mind, and ambitious young medical researchers were told that accepting a position in Folkman's lab would be the death of their careers. Now, though, the overwhelming majority of experts believes that the day will soon come when antiangiogenesis therapy supplants the current more toxic and less-effective treatments — chemotherapy, radiation, and surgery-as the preferred method of treatment for cancer in patients around the world, and Dr. Folkman's breakthrough will come to be taken for granted the way we now take for granted the polio vaccine and antibiotics. Dr. Folkman's War brilliantly describes how high the odds are against success in medical research, how vicious the competition for grants, how entrenched the skepticism about any genuinely original thinking, how polluted by politics and commerce the process of getting medicine into patients' hands. But it also depicts with rare power how exalted a calling medicine can be and how for the rare few—the brilliant, the tireless, and the lucky — the results of success can be world-changing. From the Hardcover edition.

Angiogenesis

Angiogenesis PDF Author: William D. Figg
Publisher: Springer Science & Business Media
ISBN: 0387715185
Category : Medical
Languages : en
Pages : 592

Get Book Here

Book Description
Dr. Judah Folkman is considered the "father of angiogenesis." Because of Folkman's discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. Angiogenesis: An Integrative Approach from Science to Medicine is a comprehensive, concise summary of tumor angiogenesis. It is an up-to-date and authoritative reference for the angiogenesis field as it relates to oncology. This book represents the first collection in a volume of which Folkman is co-editor. Folkman has authored nearly 400 original papers and more than 100 book chapters.

Breast Cancer Basics and Beyond

Breast Cancer Basics and Beyond PDF Author: Delthia Ricks
Publisher: Hunter House
ISBN: 9780897934541
Category : Health & Fitness
Languages : en
Pages : 388

Get Book Here

Book Description
Having breast cancer can be devastating for the woman affected - and for her family and loved ones. It can also be confusing, because there are many variations of the disease and at least as many treatments. By bringing together comprehensive information on the subject, Breast Cancer Basics and Beyond helps women better understand their illness and participate in making decisions about all aspects of their treatment and care. In this book, award-winning medical writer Delthia Ricks tells you all about: common and rare types of breast cancer, their causes and symptoms, diagnosis, including mammography and different kinds of biopsies, treatment options, including lumpectomy, mastectomy, chemotherapy, radiation and hormone therapy, benefits and side effects of the most commonly used drugs, your risk factors, including ethnicity, genetics, hormones and diet, life after cancer, follow-up care and dealing with recurrence, reasons for hope: breast cancer research and treatments in development.

The Truth in Small Doses

The Truth in Small Doses PDF Author: Clifton Leaf
Publisher: Simon and Schuster
ISBN: 1476739986
Category : History
Languages : en
Pages : 513

Get Book Here

Book Description
A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.

The Emperor of All Maladies

The Emperor of All Maladies PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1439170916
Category : Health & Fitness
Languages : en
Pages : 624

Get Book Here

Book Description
Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Saving Sight

Saving Sight PDF Author: Andrew Lam
Publisher: Irie Books
ISBN: 9781515438953
Category : Medical
Languages : en
Pages : 232

Get Book Here

Book Description
In Saving Sight, Dr. Andrew Lam explains the intricacies of human sight and shines a light on the heroes who fought to save it, while also revealing the personal side of life as an eye surgeon - the stress and joy of a man who, on his best days, can turn darkness into light. Many remarkable life stories illuminate this autobiographical/biographical/historical work. Included are Louis Braille, Judah Folkman, Harold Ridley and many others who have enabled us to see in all kinds of unimaginable ways.

Loonshots

Loonshots PDF Author: Safi Bahcall
Publisher: St. Martin's Press
ISBN: 1250185971
Category : Business & Economics
Languages : en
Pages : 366

Get Book Here

Book Description
* Instant WSJ bestseller * Translated into 18 languages * #1 Most Recommended Book of the year (Bloomberg annual survey of CEOs and entrepreneurs) * An Amazon, Bloomberg, Financial Times, Forbes, Inc., Newsweek, Strategy + Business, Tech Crunch, Washington Post Best Business Book of the year * Recommended by Bill Gates, Daniel Kahneman, Malcolm Gladwell, Dan Pink, Adam Grant, Susan Cain, Sid Mukherjee, Tim Ferriss Why do good teams kill great ideas? Loonshots reveals a surprising new way of thinking about the mysteries of group behavior that challenges everything we thought we knew about nurturing radical breakthroughs. Bahcall, a physicist and entrepreneur, shows why teams, companies, or any group with a mission will suddenly change from embracing new ideas to rejecting them, just as flowing water will suddenly change into brittle ice. Mountains of print have been written about culture. Loonshots identifies the small shifts in structure that control this transition, the same way that temperature controls the change from water to ice. Using examples that range from the spread of fires in forests to the hunt for terrorists online, and stories of thieves and geniuses and kings, Bahcall shows how a new kind of science can help us become the initiators, rather than the victims, of innovative surprise. Over the past decade, researchers have been applying the tools and techniques of this new science—the science of phase transitions—to understand how birds flock, fish swim, brains work, people vote, diseases erupt, and ecosystems collapse. Loonshots is the first to apply this science to the spread of breakthrough ideas. Bahcall distills these insights into practical lessons creatives, entrepreneurs, and visionaries can use to change our world. Along the way, readers will learn how chickens saved millions of lives, what James Bond and Lipitor have in common, what the movie Imitation Game got wrong about WWII, and what really killed Pan Am, Polaroid, and the Qing Dynasty. “If The Da Vinci Code and Freakonomics had a child together, it would be called Loonshots.” —Senator Bob Kerrey

Indispensable

Indispensable PDF Author: Gautam Mukunda
Publisher: Harvard Business Press
ISBN: 1422186709
Category : Business & Economics
Languages : en
Pages : 318

Get Book Here

Book Description
The author helps readers figure out which leaders matter, why, and when - and what lessons they can learn from those who do matter. Leaders from politics and business are profiled, they include: Abraham Lincoln, Neville Chamberlain, Woodrow Wilson, Thomas Jefferson, Winston Churchill, Jamie Dimon, Al Dunlap, Sir Jacky Fisher, and Judah Folkman.

Coping with Stress

Coping with Stress PDF Author: C. R. Snyder
Publisher: Oxford University Press
ISBN: 0190284811
Category : Social Science
Languages : en
Pages : 336

Get Book Here

Book Description
This is a companion volume to Coping: The Psychology of What Works, which is also edited by Snyder. This second book includes chapters by some of the most well known clinical and health psychologists and covers some of the newest and most provocative topics currently under study in the area of coping. The contributors address the key questions in this literature: Why do some of us learn from hardship and life's stressors? And why do others fail and succumb to depression, anxiety, and even suicide? What are the adaptive patterns and behaviors of those who do well in spite of the obstacles that are thrown their way? The chapters will look at exercise as a way of coping with stress, body imaging, the use of humor, forgiveness, control of hostile thoughts, ethnicity and coping, sexism and coping aging and relationships, constructing a coherent life story, personal spirituality, and personal growth.

Dr. Folkman's War

Dr. Folkman's War PDF Author: Robert Cooke
Publisher: Random House Digital, Inc.
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 400

Get Book Here

Book Description
This electrifying, intimate account is the exclusive inside story of cancer pioneer Judah Folkman's 35-year pursuit of an idea that is revolutionizing the way cancer is treated around the world.