Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045878
Category : Science
Languages : en
Pages : 199
Book Description
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.
DNA Technology in Forensic Science
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045878
Category : Science
Languages : en
Pages : 199
Book Description
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.
Publisher: National Academies Press
ISBN: 0309045878
Category : Science
Languages : en
Pages : 199
Book Description
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.
The Evaluation of Forensic DNA Evidence
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309121949
Category : Science
Languages : en
Pages : 271
Book Description
In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
Publisher: National Academies Press
ISBN: 0309121949
Category : Science
Languages : en
Pages : 271
Book Description
In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
Forensic DNA Technology
Author: Mark A. Farley
Publisher: CRC Press
ISBN: 1351089021
Category : Law
Languages : en
Pages : 443
Book Description
Forensic DNA Technology examines the legal and scientific issues relating to the implementation of DNA print technology in both the crime laboratory and the courtroom. Chapters have been written by many of the country's leading experts and trace the underlying theory and historical development of this technology, as well as the methodology utilized in the Restriction Fragment Length Polymorphism (RFLP) and Polymerase Chain Reaction (PCR) techniques. The effect of environmental contaminants on the evidence and the statistical analysis of population genetics data as it relates to the potential of this technology for individualizing the donor of the questioned sample are also addressed. Other topics include the proposed guidelines for using this technology in the crime laboratory, the perspective of the prosecution and the defense, the legal standards for determining the admissibility and weight of such evidence at trial. Finally, the issues of validation and the standards for interpretation of autoradiograms are brought into focus in a detailed study of actual case work. Forensic scientists, prosecuting attorneys, defense attorneys, libraries, and all scientists working with DNA technology should consider this a "must have" book.
Publisher: CRC Press
ISBN: 1351089021
Category : Law
Languages : en
Pages : 443
Book Description
Forensic DNA Technology examines the legal and scientific issues relating to the implementation of DNA print technology in both the crime laboratory and the courtroom. Chapters have been written by many of the country's leading experts and trace the underlying theory and historical development of this technology, as well as the methodology utilized in the Restriction Fragment Length Polymorphism (RFLP) and Polymerase Chain Reaction (PCR) techniques. The effect of environmental contaminants on the evidence and the statistical analysis of population genetics data as it relates to the potential of this technology for individualizing the donor of the questioned sample are also addressed. Other topics include the proposed guidelines for using this technology in the crime laboratory, the perspective of the prosecution and the defense, the legal standards for determining the admissibility and weight of such evidence at trial. Finally, the issues of validation and the standards for interpretation of autoradiograms are brought into focus in a detailed study of actual case work. Forensic scientists, prosecuting attorneys, defense attorneys, libraries, and all scientists working with DNA technology should consider this a "must have" book.
Fundamentals of Forensic DNA Typing
Author: John M. Butler
Publisher: Academic Press
ISBN: 0080961762
Category : Law
Languages : en
Pages : 519
Book Description
Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. - Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect - Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout - Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
Publisher: Academic Press
ISBN: 0080961762
Category : Law
Languages : en
Pages : 519
Book Description
Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. - Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect - Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout - Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
Advanced Topics in Forensic DNA Typing: Interpretation
Author: John M. Butler
Publisher: Academic Press
ISBN: 012405854X
Category : Social Science
Languages : en
Pages : 609
Book Description
Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. - Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence - Worked mixture examples illustrate the impact of different statistical approaches for reporting results - Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011
Publisher: Academic Press
ISBN: 012405854X
Category : Social Science
Languages : en
Pages : 609
Book Description
Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. - Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence - Worked mixture examples illustrate the impact of different statistical approaches for reporting results - Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011
Forensic DNA Applications
Author: Dragan Primorac
Publisher: CRC Press
ISBN: 1466580224
Category : Law
Languages : en
Pages : 652
Book Description
Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.
Publisher: CRC Press
ISBN: 1466580224
Category : Law
Languages : en
Pages : 652
Book Description
Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.
DNA In Forensic Science
Author: James R. Robertson
Publisher: CRC Press
ISBN: 0203015150
Category : Law
Languages : en
Pages : 212
Book Description
An up-to-date treatment of DNA in forensic science, which contains an introduction to the underlying science, and lays the foundation for a discussion of the technology and methods used. It also addresses current applications of DNA techniques.; Topics covered include structure, function and variation in DNA, experimental techniques, hypervariant a
Publisher: CRC Press
ISBN: 0203015150
Category : Law
Languages : en
Pages : 212
Book Description
An up-to-date treatment of DNA in forensic science, which contains an introduction to the underlying science, and lays the foundation for a discussion of the technology and methods used. It also addresses current applications of DNA techniques.; Topics covered include structure, function and variation in DNA, experimental techniques, hypervariant a
Forensic DNA Biology
Author: Kelly M. Elkins
Publisher: Academic Press
ISBN: 0123945852
Category : Law
Languages : en
Pages : 226
Book Description
A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.
Publisher: Academic Press
ISBN: 0123945852
Category : Law
Languages : en
Pages : 226
Book Description
A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.
Forensic DNA Typing
Author: John M. Butler
Publisher: Elsevier
ISBN: 0080470610
Category : Social Science
Languages : en
Pages : 679
Book Description
Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable. This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. *The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome*Chapters cover the topic from introductory level right up to "cutting edge" research*High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases*NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions
Publisher: Elsevier
ISBN: 0080470610
Category : Social Science
Languages : en
Pages : 679
Book Description
Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable. This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. *The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome*Chapters cover the topic from introductory level right up to "cutting edge" research*High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases*NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions
Silent Witness
Author: Henry A. Erlich
Publisher:
ISBN: 0190909447
Category : Law
Languages : en
Pages : 417
Book Description
Since its introduction in the late 1980s, DNA analysis has revolutionized the forensic sciences: it has helped to convict the guilty, exonerate the wrongfully convicted, identify victims of mass atrocities, and reunite families whose members have been separated by war and repressive regimes. Yet, many of the scientific, legal, societal, and ethical concepts that underpin forensic DNA analysis remain poorly understood, and their application often controversial. Told by over twenty experts in genetics, law, and social science, Silent Witness relates the history and development of modern DNA forensics and its application in both the courtroom and humanitarian settings. Across three thematic sections, Silent Witness tracks the scientific advances in DNA analysis and how these developments have affected criminal and social justice, whether through the arrests of new suspects, as in the case of the Golden State Killer, or through the ability to identify victims of war, terrorism, and human rights abuses, as in the cases of the disappeared in Argentina and the former Yugoslavia and those who perished during the 9/11 attacks. By providing a critical inquiry into modern forensic DNA science, Silent Witness underscores the need to balance the benefits of using forensic genetics to solve crime with the democratic right to safeguard against privacy invasion and unwarranted government scrutiny, and raises the question of what it means to be an autonomous individual in a world where the most personal elements of one's identity are now publicly accessible.
Publisher:
ISBN: 0190909447
Category : Law
Languages : en
Pages : 417
Book Description
Since its introduction in the late 1980s, DNA analysis has revolutionized the forensic sciences: it has helped to convict the guilty, exonerate the wrongfully convicted, identify victims of mass atrocities, and reunite families whose members have been separated by war and repressive regimes. Yet, many of the scientific, legal, societal, and ethical concepts that underpin forensic DNA analysis remain poorly understood, and their application often controversial. Told by over twenty experts in genetics, law, and social science, Silent Witness relates the history and development of modern DNA forensics and its application in both the courtroom and humanitarian settings. Across three thematic sections, Silent Witness tracks the scientific advances in DNA analysis and how these developments have affected criminal and social justice, whether through the arrests of new suspects, as in the case of the Golden State Killer, or through the ability to identify victims of war, terrorism, and human rights abuses, as in the cases of the disappeared in Argentina and the former Yugoslavia and those who perished during the 9/11 attacks. By providing a critical inquiry into modern forensic DNA science, Silent Witness underscores the need to balance the benefits of using forensic genetics to solve crime with the democratic right to safeguard against privacy invasion and unwarranted government scrutiny, and raises the question of what it means to be an autonomous individual in a world where the most personal elements of one's identity are now publicly accessible.