Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045878
Category : Science
Languages : en
Pages : 199
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Book Description
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.
Author: Dragan Primorac
Publisher: CRC Press
ISBN: 1466580224
Category : Law
Languages : en
Pages : 652
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Book Description
Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.
Author: Erin E Murphy
Publisher: Bold Type Books
ISBN: 1568584709
Category : Social Science
Languages : en
Pages : 399
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Book Description
Josiah Sutton was convicted of rape. He was five inches shorter and 65 pounds lighter than the suspect described by the victim, but at trial a lab analyst testified that his DNA was found at the crime scene. His case looked like many others -- arrest, swab, match, conviction. But there was just one problem -- Sutton was innocent. We think of DNA forensics as an infallible science that catches the bad guys and exonerates the innocent. But when the science goes rogue, it can lead to a gross miscarriage of justice. Erin Murphy exposes the dark side of forensic DNA testing: crime labs that receive little oversight and produce inconsistent results; prosecutors who push to test smaller and poorer-quality samples, inviting error and bias; law-enforcement officers who compile massive, unregulated, and racially skewed DNA databases; and industry lobbyists who push policies of "stop and spit." DNA testing is rightly seen as a transformative technological breakthrough, but we should be wary of placing such a powerful weapon in the hands of the same broken criminal justice system that has produced mass incarceration, privileged government interests over personal privacy, and all too often enforced the law in a biased or unjust manner. Inside the Cell exposes the truth about forensic DNA, and shows us what it will take to harness the power of genetic identification in service of accuracy and fairness.
Author: Amanda C Sozer
Publisher: CRC Press
ISBN: 1466513845
Category : Law
Languages : en
Pages : 318
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Book Description
Advances in DNA technology have expanded such that forensic DNA profiling is now considered a routine method for identifying victims of mass fatalities. Originating from an initiative funded by a grant from the U.S. Department of State, DNA Analysis for Missing Person Identification in Mass Fatalities presents a collection of training modules that supply comprehensive instruction in these complex techniques. The book begins with a concise overview of DNA analysis methods and their use in identifying victims of mass fatalities. It then goes on to explore: Mass fatality response operations, including body recovery, mortuary operations, family assistance, the identification of human remains, and psychosocial support for families Best practices in DNA sample collection and the different types of reference samples that can be used to identify a reported missing (RM) individual Autosomal short tandem repeat (STR) DNA profile analysis and interpretation, and procedures to ensure data accuracy Major steps involved in generating a DNA profile and the complex aspects of data analysis and interpretation The importance of data management using information technology tools, and tips for maintaining quality operations Accreditation and standards and the major elements of a DNA quality program Setting up a laboratory operation, including planning, staffing, identifying types of equipment and supplies, and the procedures for ensuring that laboratory equipment performs appropriately The book includes a discussion of the key steps in the preparation, delivery, and evaluation of training sessions for personnel responding to a mass fatality human identification event. It also provides a comprehensive vocabulary list with terms related to mass fatality DNA identification. This text is a must-read for organizations contemplating the use of DNA in human identification initiatives following mass fatalities. It is also a tremendous value to emergency manager/planners, medical legal authorities, and forensic DNA laboratories.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309134404
Category : Science
Languages : en
Pages : 270
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Book Description
In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
Author: Mannon E. Gallegly
Publisher:
ISBN: 9780890543641
Category : Phytophthora
Languages : en
Pages : 0
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Book Description
The dichotomous key uses minimal morphological characters, followed by pictorial illustrations.
Author: Eric A. Fischer
Publisher: Nova Biomedical Books
ISBN:
Category : Law
Languages : en
Pages : 86
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Book Description
This book provides an overview of how the genetic information contained in DNA is used for identification, and a discussion of issues associated with those uses. It begins by discussing the unique properties of genetic information that make it a powerful tool for identification and what is involved in making identifications from DNA. Next is a description of current federal programs and activities, followed by discussion of issues raised by the development of this new technology. Major issues include the use of DNA identification in the criminal justice system (including sample backlogs, databases, and post-conviction DNA analysis), impacts of technological improvements, and privacy. DNA evidence is a powerful forensic tool in criminal cases. Its use and capabilities have increased substantially since it was first introduced in the late 1980s. A DNA profile may provide powerful evidence in many criminal investigations, either to incriminate or exculpate a suspect. DNA evidence is very stable and can be extracted and profiled from a sample many years after being deposited. The technologies used are increasingly sensitive, powerful, fast, and cost-effective. The cost of performing analyses and the time required continue to decline. Those features of the technology are likely to continue to improve over the next decade.
Author: Blaine Bettinger
Publisher: Penguin
ISBN: 1440300585
Category : Reference
Languages : en
Pages : 274
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Book Description
Unlock the family secrets in your DNA! Discover the answers to your family history mysteries using the most cutting edge tool available. This plain-English guide (newly updated and expanded to include th latest DNA developments) will teach you what DNA tests are available; the pros and cons of the major testing companies; and how to choose the right test to answer your specific genealogy questions. And once you've taken a DNA test, this guide will help you use your often-overwhelming results, with tips for understanding ethnicity estimates, navigating suggested cousin matches, and using third-party tools like GEDmatch to further analyze your data. The book features: · Colorful diagrams and expert definitions that explain key DNA terms and concepts such as haplogroups and DNA inheritance patterns · Detailed guides to each of the major kinds of DNA tests and tips for selecting the DNA test that can best help you solve your family mysteries, with case studies showing how each can be useful · Information about third-party tools you can use to more thoroughly analyze your test results once you've received them · Test comparison guides and research forms to help you select the most appropriate DNA test and organize your results · Insights into how adoptees and others who know little about their ancestry can benefit from DNA testing Whether you've just heard of DNA testing or you've tested at all three major companies, this guide will give you the tools you need to unpuzzle your DNA and discover what it can tell you about your family tree.
Author: Angie Ambers
Publisher: Academic Press
ISBN: 0128163690
Category : Law
Languages : en
Pages : 628
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Book Description
Forensic Genetic Approaches for Identification of Human Skeletal Remains: Challenges, Best Practices, and Emerging Technologies provides best practices on processing bone samples for DNA testing. The book outlines forensic genetics tools that are available for the identification of skeletal remains in contemporary casework and historical/archaeological investigations. Although the book focuses primarily on the use of DNA for direct identification or kinship analyses, it also highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting. Unidentified human remains are often associated with tragic events, such as fires, terrorist attacks, natural disasters, war conflicts, genocide, airline crashes, homicide, and human rights violations under oppressive totalitarian regimes. In these situations, extensive damage to soft tissues often precludes the use of such biological samples in the identification process. In contrast, bone material is the most resilient, viable sample type for DNA testing. DNA recovered from bone often is degraded and in low quantities due to the effects of human decomposition, environmental exposure, and the passage of time. The complexities of bone microstructure and its rigid nature make skeletal remains one of the most challenging sample types for DNA testing. Provides best practices on processing bone samples for DNA testing Presents detailed coverage of proper facilities design for skeletal remains processing, selection of optimal skeletal elements for DNA recovery, specialized equipment needed, preparation and cleaning of bone samples for DNA extraction, and more Highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting
Author: Victor A. Bernstam
Publisher: CRC Press
ISBN: 1498710611
Category : Medical
Languages : en
Pages : 561
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Book Description
Pocket Guide to Gene Level Diagnostics in Clinical Practice is an abbreviated, pocket-size, quick-reference guide that provides a point-by-point synopsis of the vast wealth of information contained in CRC Handbook of Gene Level Diagnostics in Clinical Practice. All sections and subsections in the Pocket Guide are cross-referenced to corresponding pages in the Handbook. The book works well on its own as a quick reference, but also can be used in conjunction with the larger Handbook for detailed coverage and references to specific information. Pocket Guide to Gene Level Diagnostics in Clinical Practice also includes extensive supplements featuring material not included in the Handbook. These are intended to provide an up-dated, practical source of information useful to anyone involved in molecular diagnostic research and/or service. Supplements are cross-referenced to the main text of the Pocket Guide, that complement and enhance the material covered. Pocket Guide to Gene Level Diagnostics in Clinical Practice will be a handy reference for professionals and students in pathology, biotechnology, biology, and medicine.
