Molecular Biology of The Cell PDF Download
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Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: Eric T. Kool
Publisher: Pergamon
ISBN: 9780080431659
Category : DNA.
Languages : en
Pages : 0
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Book Description
This volume is intended to cover the chemistry of one of the most widely studied and important natural products, DNA. Discussed in detail are physicochemical properties of the molecule itself as well as small-molecule natural products that are known to interact with it. Also included are methods to synthesize and manipulate DNA and modified analogues. Twenty chapters are devoted to this overall topic. thermodynamics and kinetics of double helix formation; the next two describe triple- and tetra- helical structures formed by DNA; and the last two focus on methods for probing DNA structure (specifically, NMR methods and chemical probing methods, respectively). analogues. The first of these addresses nonenzymatic methods for synthesizing DNA, and the next chapter, methods for attachment of reporter groups to it. Modifications of DNA structure are discussed in chapters eight to eleven; the first of these addresses nucleoside analogues useful as biochemical probes, while others discuss alterations to the DNA backbone, bases, and topology, respectively. The extensive chemistry of DNA damage is reviewed in the last chapter (chapter 12). Included in this group are a large number of natural and non-natural products, which fall into the classes of intercalators (chapter 13), minor groove binders (chapter 14), DNA-binding peptides (chapter 15), and DNA-damaging natural products (chapter 16). The last two chapters focus more specifically on two broad classes of medicinally important agents which interact with DNA; specifically, the enediyne natural products (chapter 17), and topoisomerase inhibitors (chapter 18). are being used in many chemically-oriented laboratories. The first (chapter 19) covers selection of novel ligands and catalysts from sequence-randomized libraries of DNA. The second (chapter 20) covers other useful molecular biology methods such as cloning and the polymerase chain reaction.
Author: Chang-Hui Shen
Publisher: Elsevier
ISBN: 0323986099
Category : Science
Languages : en
Pages : 590
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Book Description
Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine. Provides explanations on how techniques are used to diagnosis at the molecular level Explains how to use information technology to communicate and assess results in the lab Enhances our understanding of fundamental molecular biology and places techniques in context Places protocols into context with practical applications Includes extra chapters on respiratory viruses (Corona)
Author: Derek H. R. Barton
Publisher: Elsevier Publishing Company
ISBN:
Category : Science
Languages : en
Pages : 780
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Book Description
Hardbound. This volume is intended to cover the chemistry of one of the most widely studied and important natural products, DNA. Discussed in detail are physicochemical properties of the molecule itself as well as small-molecule natural products that are known to interact with it. Also included are methods to synthesize and manipulate DNA and modified analogues. Twenty chapters are devoted to this overall topic.The first five relate to the structure of DNA; the first focuses on thermodynamics and kinetics of double helix formation; the next two describe triple- and tetra- helical structures formed by DNA; and the last two focus on methods for probing DNA structure (specifically, NMR methods and chemical probing methods, respectively).Chapters 6-12 focus on the chemistry of natural DNA and modified analogues. The first of these addresses nonenzymatic methods for synthesizing DNA, and the next chapter, on methods for attachment of reporter groups t
Author: Michael Fry
Publisher: Academic Press
ISBN: 012802108X
Category : Science
Languages : en
Pages : 572
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Book Description
Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling
Author: Frank H. Stephenson
Publisher: Academic Press
ISBN: 012375691X
Category : Science
Languages : en
Pages : 520
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Book Description
Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing. Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text New to this Edition: Updated and increased coverage of real time PCR and the mathematics used to measure gene expression More sample problems in every chapter for readers to practice concepts
Author: Burton E. Tropp
Publisher: Jones & Bartlett Learning
ISBN: 9780763709167
Category : Medical
Languages : en
Pages : 1032
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Book Description
Molecular Biology or Molecular Genetics - Biology Department Biochemical Genetics - Biology or Biochemistry Department Microbial Genetics - Genetics Department The book is typically used in a one-semester course that may be taught in the fall or the spring. However, the book contains sufficient information so that it could be used for a full year course. It is appropriate for juniors and seniors or first year graduate students.
Author: Nancy Craig
Publisher: Oxford University Press
ISBN: 0199658579
Category : Science
Languages : en
Pages : 945
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Book Description
The biological world operates on a multitude of scales - from molecules to tissues to organisms to ecosystems. Throughout these myriad levels runs a common thread: the communication and onward passage of information, from cell to cell, from organism to organism and ultimately, from generation to generation. But how does this information come alive to govern the processes that constitute life? The answer lies in the molecular components that cooperate through a series of carefully-regulated processes to bring the information in our genome to life. These components and processes lie at the heart of one of the most fascinating subjects to engage the minds of scientists today: molecular biology. Molecular Biology: Principles of Genome Function, Second Edition, offers a fresh approach to the teaching of molecular biology by focusing on the commonalities that exist between the three kingdoms of life, and discussing the differences between the three kingdoms to offer instructive insights into molecular processes and components. This gives students an accurate depiction of our current understanding of the conserved nature of molecular biology, and the differences that underpin biological diversity. Additionally, an integrated approach demonstrates how certain molecular phenomena have diverse impacts on genome function by presenting them as themes that recur throughout the book, rather than as artificially separated topics As an experimental science, molecular biology requires an appreciation for the approaches taken to yield the information from which concepts and principles are deduced. Experimental Approach panels throughout the text describe research that has been particularly valuable in elucidating difference aspects of molecular biology. Each panel is carefully cross-referenced to the discussion of key molecular biology tools and techniques, which are presented in a dedicated chapter at the end of the book. Molecular Biology further enriches the learning experience with full-color artwork, end-of-chapter questions and summaries, suggested further readings grouped by topic, and an extensive glossary of key terms. Features: A focus on the underlying principles of molecular biology equips students with a robust conceptual framework on which to build their knowledge An emphasis on their commonalities reflects the processes and components that exist between bacteria, archae, and eukaryotes Experimental Approach panels demonstrate the importance of experimental evidence by describing research that has been particularly valuable in the field
Author: Burton E. Tropp
Publisher: Jones & Bartlett Publishers
ISBN: 144964791X
Category : Science
Languages : en
Pages : 781
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Book Description
Includes access to the Student Companion Website with every print copy of the text.Written for the more concise course, Principles of Molecular Biology is modeled after Burton Tropp's successful Molecular Biology: Genes to Proteins and is appropriate for the sophomore level course. The author begins with an introduction to molecular biology, discussing what it is and how it relates to applications in "real life" with examples pulled from medicine and industry. An overview of protein structure and function follows, and from there the text covers the various roles of technology in elucidating the central concepts of molecular biology, from both a historical and contemporary perspective. Tropp then delves into the heart of the book with chapters focused on chromosomes, genetics, replication, DNA damage and repair, recombination, transposition, transcription, and wraps up with translation.Key Features:- Presents molecular biology from a biochemical perspective, utilizing model systems, as they best describe the processes being discussed-Special Topic boxes throughout focus on applications in medicine and technology-Presents "real world" applications of molecular biology that are necessary for students continuing on to medical school or the biotech industry-An end-of-chapter study guide includes questions for review and discussion-Difficult or complicated concepts are called-out in boxes to further explain and simplify
Author: G.P. JEYANTHI
Publisher: MJP Publisher
ISBN:
Category : Science
Languages : en
Pages : 468
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Book Description
Genetic Material Chemistry of Deoxyribonucleic Acid Structural Features of Deoxyribonucleic Acid Properties of Deoxyribonucleic Acid Prokaryotic and Eukaryotic Chromosomes Replication and Repair of Deoxyribonucleic Acid Ribonucleic Acid and TranscriptionThe Genetic Code Mutations and Molecular Mechanism of Mutagenesis Translation Regulation of Gene Expression in Prokaryotes Regulation of Gene Expression in Eukaryotes Analytical Techniques used in the Study of Nucleic Acids
