Discovering Molecular Genetics PDF Download
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Author:
Publisher: CSHL Press
ISBN: 9788796947501
Category :
Languages : en
Pages : 730
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Book Description
Author:
Publisher: CSHL Press
ISBN: 9788796947501
Category :
Languages : en
Pages : 730
Get Book Here
Book Description
Author: Jeffrey H. Miller
Publisher: CSHL Press
ISBN: 9780879694821
Category : Science
Languages : en
Pages : 88
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Book Description
This is the companion volume to "Discovering Molecular Genetics: A Case Study Course with Problems and Scenarios" (ISBN 0-87969-475-0), which offers teachers a one-semester course in molecular genetics for use by life science majors (microbiology, biochemistry, molecular biology or biology) or pre-med students. This manual offers solutions and strategies for the 140 problems in its companion text, covering scenarios from history, mythology, films and television, which test students' abilities to apply molecular genetic concepts. The case study book is adapted from a course in molecular genetics given by the author at the University of California in Los Angeles, USA.
Author: Michael Fry
Publisher: Academic Press
ISBN: 012802108X
Category : Science
Languages : en
Pages : 572
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Book Description
Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. - Includes detailed analysis of classically designed and executed experiments - Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries - Provides critical analysis of the history of molecular biology to inform the future of scientific discovery - Examines the machinery of inheritance and biological information handling
Author: Graeme K. Hunter
Publisher: Academic Press
ISBN: 9780123618115
Category : History
Languages : en
Pages : 408
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Book Description
Vital Forces tells the history of the 'biochemical revolution', a period of unprecedentedly rapid advance in human knowledge that profoundly affected our view of life and laid the foundation for modern medicine and biotechnology. The story is told in a clear, engaging, and absorbing manner. This delightful work relates the fascinating and staggering advances in concepts and theories over the last 200 years and introduces the major figures of the times. Vital Forces also describes the discovery of the molecular basis of life through the stories of the scientists involved, including such towering figures as Louis Pasteur, Gregor Mendel, Linus Pauling, and Francis Crick. Combining science and biography into a seamless chronological narrative, the author brings to life the successes and failures, collaborations and feuds, and errors and insights that produced the revolution in biology. * Vividly describes dramatic scientific discoveries, personalities, feuds and rivalries * Answers a general readers quest to understand the nature of life, and the relevance of biochemistry/molecular biology to modern medicine, industry and agriculture.
Author: Richard S. Larson
Publisher: Humana Press
ISBN: 9781588293466
Category : Medical
Languages : en
Pages : 444
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Book Description
A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.
Author: Jack J. Pasternak
Publisher: John Wiley & Sons
ISBN: 047171917X
Category : Science
Languages : en
Pages : 656
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Book Description
An Introduction to Human Molecular Genetics Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expandsits coverage of the molecular genetics of inherited human diseaseswith the latest research findings and discoveries. Using a unique,systems-based approach, the text offers readers a thoroughexplanation of the gene discovery process and how defective genesare linked to inherited disease states in major organ and tissuesystems. All the latest developments in functional genomics,proteomics, and microarray technology have been thoroughlyincorporated into the text. The first part of the text introduces readers to the fundamentalsof cytogenetics and Mendelian genetics. Next, techniques andstrategies for gene manipulation, mapping, and isolation areexamined. Readers will particularly appreciate the text'sexceptionally thorough and clear explanation of genetic mapping.The final part features unique coverage of the molecular geneticsof distinct biological systems, covering muscle, neurological, eye,cancer, and mitochondrial disorders. Throughout the text, helpfulfigures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text'ssame lucid and engaging style, and will find a wealth of new andexpanded material that brings them fully up to date with a currentunderstanding of the field, including: * New chapters on complex genetic disorders, genomic imprinting,and human population genetics * Expanded and fully revised section on clinical genetics, coveringdiagnostic testing, molecular screening, and varioustreatments This text is targeted at upper-level undergraduate students,graduate students, and medical students. It is also an excellentreference for researchers and physicians who need a clinicallyrelevant reference for the molecular genetics of inherited humandiseases.
Author: Jan Anthony Witkowski
Publisher:
ISBN: 9781621821083
Category : Biography & Autobiography
Languages : en
Pages : 0
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Book Description
The Road to Discovery: A Short History of Cold Spring Harbor Laboratory was published in 2015 to mark the 125th anniversary of Cold Spring Harbor Laboratory. At Cold Spring Harbor, in a bucolic setting on the north shore of New York's Long Island, two interdependent research centers in biology were founded as Charles Darwin's insights into heredity and evolution shook the world of science. Fifty years later, those centers would emerge as a single institution that would cradle another revolution, the new science of molecular biology, and advance to world renown in research and professional education. It is a remarkable story, with a path of progress that was neither simple nor assured. The Road to Discovery traces half a century of changes in name, leadership, governance, and financial fortune. And scientific missteps, most notoriously in eugenics, were triumphed by innovative work in genetics, human metabolism, and cancer. From the 1940s through the 1960s, the Laboratory was home to fundamental discoveries about the nature of genetic material and a cauldron of critical assessment of ideas about genes by sharp-tongued summer visitors. James D. Watson, a junior member of that group, would go on to deduce the structure of DNA with Francis Crick in 1953 and help create the new field of molecular genetics before returning to Cold Spring Harbor as Director 15 years later. As the book shows, his "Bold Plan" would inspire, cajole, and goad into existence an era of expansion, new research directions, and initiatives in conferences, courses, publishing, and education that redefined the scope of the Laboratory. Under Bruce Stillman's leadership, that scope has grown still more, making the Laboratory unique among research institutions worldwide--envied, imitated, but not reproduced. The book's author is the science historian Jan Witkowski. His knowledge of the subject is wide and his affection for it deep. He brings to his task insights that only a decades-long career as a staff member can provide. For over a century, the Laboratory has been influenced by exceptional personalities, outstanding achievements, and dramatic events. The Road to Discovery captures that history in a lively narrative illuminated by vignettes on the importance of individual scientists and their discoveries. Abundantly documented with material from the Laboratory's archives, it is an accessible book that will appeal to anyone interested in the development of biomedical science and biotechnology through the 20th century to the present day.
Author: Maclyn McCarty
Publisher: W. W. Norton & Company
ISBN: 9780393304503
Category : Philosophy
Languages : en
Pages : 258
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Book Description
Forty years ago, three medical researchers--Oswald Avery, Colin MacLeod, and Maclyn McCarty--made the discovery that DNA is the genetic material. With this finding was born the modern era of molecular biology and genetics.
Author: Richard S. Larson
Publisher:
ISBN: 9781617799655
Category : Bioinformatics
Languages : en
Pages : 374
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Book Description
Recent advances in drug discovery have been rapid. The second edition of Bioinformatics and Drug Discovery has been completely updated to include topics that range from new technologies in target identification, genomic analysis, cheminformatics, protein analysis, and network or pathway analysis. Each chapter provides an extended introduction that describes the theory and application of the technology. In the second part of each chapter, detailed procedures related to the use of these technologies and software have been incorporated. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Bioinformatics and Drug Discovery, Second Edition seeks to aid scientists in the further study of the rapidly expanding field of drug discovery.
Author: Robert T. Gerlai
Publisher: Academic Press
ISBN: 0128041161
Category : Science
Languages : en
Pages : 710
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Book Description
Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts
