Dietary Estrogens and Hormone Dependent Mammary Cancer PDF Download
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Author: Kathey M. Verdeal
Publisher:
ISBN:
Category : Breast
Languages : en
Pages : 300
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Book Description
Author: Kathey M. Verdeal
Publisher:
ISBN:
Category : Breast
Languages : en
Pages : 300
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Book Description
Author: I Rowland
Publisher: Elsevier
ISBN: 0323147054
Category : Medical
Languages : en
Pages : 528
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Book Description
Role of the Gut Flora in Toxicity and Cancer examines the relationship between the gut microflora and its host. The aim is to provide a comprehensive view of the contribution of the gut flora to foreign compound metabolism in man and laboratory animals. The object has been to relate this bacterial metabolism to toxic events occurring in mammals and to consider the interrelationships of bacterial and mammalian metabolic pathways. The early chapters are set the scene and provide a background to the sections on metabolism of specific groups of compounds which follow. Subsequent chapters encompass the bacterial metabolism of both xenobiotics and food components, and concentrate on those reactions which have actual or potential toxicological and/or clinical importance. The concluding chapters provide assessments of the role of the gut flora in the etiology of cancer, in particular from the point of view of the formation of carcinogens, mutagens, and promotors within the large bowel.
Author: Tobias Pischon
Publisher: Springer
ISBN: 3319425420
Category : Medical
Languages : en
Pages : 258
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Book Description
This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.
Author: Maryce M. Jacobs
Publisher: Springer Science & Business Media
ISBN: 1489909397
Category : Medical
Languages : en
Pages : 267
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Book Description
The American Institute for Cancer Research (AICR) sponsored its third annual confer ence on nutrition and cancer. The theme was "Diet and Cancer: Markers, Prevention, and Treatment. " The conference was held October 29-30, 1992 at the Ritz Carlton Hotel in McLean, Virginia. This proceedings contains chapters from the platform presentations and abstracts from the poster presentations. Several chapters address each of four session topics: Retinoids as Differentiation Agents in Cancer Therapy, Biological Markers of Cancer Risk, Chemoprevention of Cancer by Non-Nutrients in Foods, and Nutritional Problems and Support in the Treatment of Cancer. The first three chapters discuss in detail different mechanisms by which retinoids influence differentiation and provide evidence to support their use in cancer therapy. In vivo and in vitro studies show the effects of retinoic acid (RA) on tumorigenicity and cellu lar/molecular events. A synopsis of data showing the involvement of the retinoblastoma (RB) gene in HL-60 cell differentiation induced by RA and 1,2S-dihydroxy vitamin D3 (VD) is presented. In SCID (severe combined immunodeficiency) mice injected with HL-60 3 human leukemia cells and gavaged daily with RA, the number of tumor sites and number of mice with tumors are reduced. All trans-RA induces myeloid differentiation in HL-60 cells. Similarly, VD3 induces HL-60 monocytic differentiation. In both cases an early down regulation of retinoblastoma (RB) gene expression precedes the differentiation.
Author: Nanette F. Santoro
Publisher: Springer Science & Business Media
ISBN: 1603278648
Category : Medical
Languages : en
Pages : 224
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Book Description
Amenorrhea: A Case-Based Clinical Guide is a comprehensive review of the current knowledge regarding normal female reproductive physiology. Replete with interesting case vignettes and providing diagnostic algorithms and therapeutic strategies for amenorrhea, Amenorrhea: A Case-Based Clinical Guide is divided into three sections. The first section is composed of two chapters that provide a thorough review of basic science and clinical knowledge about the organ systems responsible for normal physiology of the menstrual cycle. The second section includes discussion about menstrual cycle disruption as it relates to hypothalamic-pituitary dysfunction, surgical and natural menopause, genetic defects, premature ovarian failure/insufficiency and the effects of caloric excess and restriction. The third section offers an update on the physiological effects of prolonged amenorrhea induced surgically or by hypothalamic dysfunction and also includes an original chapter that focuses solely on the impact of race and ethnicity on the prevalence and diagnosis of amenorrhea. Amenorrhea: A Case-Based Clinical Guide brings together chapters from renowned experts who offer state-of-the-art, clinically useful information in a case-based, reader-friendly fashion. This title will be a welcome addition to the bookshelves of all clinicians who practice in women’s health settings.
Author: Fatih Yildiz
Publisher: CRC Press
ISBN: 0429524811
Category : Technology & Engineering
Languages : en
Pages : 312
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Book Description
Polyphenol phytoestrogens - bioactives found in specific foods and beverages - impart antioxidant, phytoestrogenic, antiproliferative, and enzyme modulating activities within the human metabolic system. It is believed that these compounds protect against several forms of cancer, cardiovascular and neurodegenerative diseases, osteoporosis, and menop
Author: Philippa D. Darbre
Publisher: Academic Press
ISBN: 0128011203
Category : Medical
Languages : en
Pages : 390
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Book Description
Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Author: Nina Zumel
Publisher: Manning Publications
ISBN: 9781617291562
Category : Computers
Languages : en
Pages : 416
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Book Description
Summary Practical Data Science with R lives up to its name. It explains basic principles without the theoretical mumbo-jumbo and jumps right to the real use cases you'll face as you collect, curate, and analyze the data crucial to the success of your business. You'll apply the R programming language and statistical analysis techniques to carefully explained examples based in marketing, business intelligence, and decision support. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the Book Business analysts and developers are increasingly collecting, curating, analyzing, and reporting on crucial business data. The R language and its associated tools provide a straightforward way to tackle day-to-day data science tasks without a lot of academic theory or advanced mathematics. Practical Data Science with R shows you how to apply the R programming language and useful statistical techniques to everyday business situations. Using examples from marketing, business intelligence, and decision support, it shows you how to design experiments (such as A/B tests), build predictive models, and present results to audiences of all levels. This book is accessible to readers without a background in data science. Some familiarity with basic statistics, R, or another scripting language is assumed. What's Inside Data science for the business professional Statistical analysis using the R language Project lifecycle, from planning to delivery Numerous instantly familiar use cases Keys to effective data presentations About the Authors Nina Zumel and John Mount are cofounders of a San Francisco-based data science consulting firm. Both hold PhDs from Carnegie Mellon and blog on statistics, probability, and computer science at win-vector.com. Table of Contents PART 1 INTRODUCTION TO DATA SCIENCE The data science process Loading data into R Exploring data Managing data PART 2 MODELING METHODS Choosing and evaluating models Memorization methods Linear and logistic regression Unsupervised methods Exploring advanced methods PART 3 DELIVERING RESULTS Documentation and deployment Producing effective presentations
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 1060
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Book Description
Author: National Research Council
Publisher: Legare Street Press
ISBN: 9781015691629
Category : History
Languages : en
Pages : 0
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Book Description
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
