Developmental Instability

Developmental Instability PDF Author: Michal Polak
Publisher: Oxford University Press, USA
ISBN: 9780195143454
Category : Language Arts & Disciplines
Languages : en
Pages : 488

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Book Description
The field of developmental instability has generated a large amount of controversy recently, mostly because of fierce disagreement over the genetic basis of fluctuating asymmetry and its role in mate selection. This book is a timely and innovative critical evaluation of a burgeoning field. The book explores the premise that complex organismal, ecological and evolutionary processes can be understood as emergent properties of the "epigenetic machine," that is, the mechanisms fundamental to all organisms responsible for building and organizing phenotypes from information translated from DNA.

Developmental Instability

Developmental Instability PDF Author: Michal Polak
Publisher: Oxford University Press, USA
ISBN: 9780195143454
Category : Language Arts & Disciplines
Languages : en
Pages : 488

Get Book Here

Book Description
The field of developmental instability has generated a large amount of controversy recently, mostly because of fierce disagreement over the genetic basis of fluctuating asymmetry and its role in mate selection. This book is a timely and innovative critical evaluation of a burgeoning field. The book explores the premise that complex organismal, ecological and evolutionary processes can be understood as emergent properties of the "epigenetic machine," that is, the mechanisms fundamental to all organisms responsible for building and organizing phenotypes from information translated from DNA.

Asymmetry, Developmental Stability and Evolution

Asymmetry, Developmental Stability and Evolution PDF Author: Anders Pape MØller
Publisher: Oxford University Press, UK
ISBN: 019158939X
Category : Developmental biology
Languages : en
Pages : 306

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Book Description
Why does nature love symmetry? In Asymmetry, Developmental Stability and Evolution, M--oslash--;ller and Swaddle analyse the evolutionary implications of symmetry. They advance and explain their theory that asymmetry is related to genetic stability and fitness, and that symmetric individuals appear to have quantifiable and significant advantages over their asymmetric counterparts. When assessing potential mates or competitors, animals may be able to use symmetry as an honest indication of quality. This interdisciplinary book, with its associated Web-site, will be of interest to students and researchers in the fields of ecology, evolutionary biology, genetics, and animal behaviour. - ;Why does nature love symmetry? In Asymmetry, Developmental Stability and Evolution, M--oslash--;ller and Swaddle analyse the evolutionary implications of symmetry. They advance and explain their theory that symmetry is related to genetic stability and fitness, and that symmetric individuals appear to have quantifiable and significant advantages over their asymmetric counterparts. When assessing potential mates or competitors, animals may be able to use symmetry as an honest indication of quality. This interdisciplinary book, with its associated Web-site, will be of interest to students and researchers in the fields of ecology, evolutionary biology, genetics, and animal behaviour. -

Developmental Instability: Its Origins and Evolutionary Implications

Developmental Instability: Its Origins and Evolutionary Implications PDF Author: T.A. Markow
Publisher: Springer Science & Business Media
ISBN: 9401108307
Category : Science
Languages : en
Pages : 430

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Book Description
Developmental Instability: Its Origins and Evolutionary Implications is a collection of papers and transcribed discussions from a conference held in Tempe, Arizona in June 1993. The papers represent a wide range of contributions, from the empirical to the theoretical, and include methods for measuring developmental instability across a variety of taxa and traits. This volume presents contrasting views on how to assess developmental instability as well as on the relationship of instability to genotypic factors, environmental factors and the action of natural and sexual selection. Readers will derive a working knowledge of the best way to assess developmental instability and will be able to design future work in an authoritative way.

The Molecular Biology of Down Syndrome

The Molecular Biology of Down Syndrome PDF Author: G. Lubec
Publisher: Springer Science & Business Media
ISBN: 9783211833773
Category : Medical
Languages : en
Pages : 380

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Book Description
This book contains updated reviews and original research work on Down Syndrome focussing on brandnew results in neurobiology, in particular results on gene hunting (subtractive hybridization, differential display) and neurochemistry. The book provides new data such as a subtractive library of Down Syndrome brain showing cDNAs that are overexpressed or downregulated and can be regarded as a source for further research on the preliminary transcriptional data given. A 2D-electrophoretic map of human brain proteins including Down Syndrome brain protein expression established by in-gel-digestion of spots with subsequent MALDI-identification provides the scientific basis for protein work to the neuroscientist. Altogether, the book provides a series of new candidate genes possibly involved in Down Syndrome neurobiology, tools for neuroscience studies on Down Syndrome brain thus serving as a manual and updated views and aspects on Down Syndrome pathobiology.

Transforming the Workforce for Children Birth Through Age 8

Transforming the Workforce for Children Birth Through Age 8 PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309324882
Category : Social Science
Languages : en
Pages : 587

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Book Description
Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.

The Genetics of Neurodevelopmental Disorders

The Genetics of Neurodevelopmental Disorders PDF Author: Kevin J. Mitchell
Publisher: John Wiley & Sons
ISBN: 1118524888
Category : Medical
Languages : en
Pages : 384

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Book Description
Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Parenting Matters

Parenting Matters PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309388570
Category : Social Science
Languages : en
Pages : 525

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Book Description
Decades of research have demonstrated that the parent-child dyad and the environment of the familyâ€"which includes all primary caregiversâ€"are at the foundation of children's well- being and healthy development. From birth, children are learning and rely on parents and the other caregivers in their lives to protect and care for them. The impact of parents may never be greater than during the earliest years of life, when a child's brain is rapidly developing and when nearly all of her or his experiences are created and shaped by parents and the family environment. Parents help children build and refine their knowledge and skills, charting a trajectory for their health and well-being during childhood and beyond. The experience of parenting also impacts parents themselves. For instance, parenting can enrich and give focus to parents' lives; generate stress or calm; and create any number of emotions, including feelings of happiness, sadness, fulfillment, and anger. Parenting of young children today takes place in the context of significant ongoing developments. These include: a rapidly growing body of science on early childhood, increases in funding for programs and services for families, changing demographics of the U.S. population, and greater diversity of family structure. Additionally, parenting is increasingly being shaped by technology and increased access to information about parenting. Parenting Matters identifies parenting knowledge, attitudes, and practices associated with positive developmental outcomes in children ages 0-8; universal/preventive and targeted strategies used in a variety of settings that have been effective with parents of young children and that support the identified knowledge, attitudes, and practices; and barriers to and facilitators for parents' use of practices that lead to healthy child outcomes as well as their participation in effective programs and services. This report makes recommendations directed at an array of stakeholders, for promoting the wide-scale adoption of effective programs and services for parents and on areas that warrant further research to inform policy and practice. It is meant to serve as a roadmap for the future of parenting policy, research, and practice in the United States.

Adolescence and Emerging Adulthood

Adolescence and Emerging Adulthood PDF Author: Jeffrey Jensen Arnett
Publisher:
ISBN: 9780205892495
Category : Adolescence
Languages : en
Pages : 0

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Book Description
Helps students understand how culture impacts development in adolescence and emerging adulthood. Grounded in a global cultural perspective (within and outside of the US), this text enriches the discussion with historical context and an interdisciplinary approach, including studies from fields such as anthropology and sociology, in addition to the compelling psychological research on adolescent development. This book also takes into account the period of "emerging adulthood" (ages 18-25), a term coined by the author, and an area of study for which Arnett is a leading expert. Arnett continues the fifth edition with new and updated studies, both U.S. and international. With Pearson's MyDevelopmentLab Video Series and Powerpoints embedded with video, students can experience a true cross-cultural experience. A better teaching and learning experience This program will provide a better teaching and learning experience-- for you and your students. Here's how: Personalize Learning - The new MyDevelopmentLab delivers proven results in helping students succeed, provides engaging experiences that personalize learning, and comes from a trusted partner with educational expertise and a deep commitment to helping students and instructors achieve their goals. Improve Critical Thinking - Students learn to think critically about the influence of culture on development with pedagogical features such as Culture Focus boxes and Historical Focus boxes. Engage Students - Arnett engages students with cross cultural research and examples throughout. MyVirtualTeen, an interactive simulation, allows students to apply the concepts they are learning to their own "virtual teen." Explore Research - "Research Focus" provides students with a firm grasp of various research methods and helps them see the impact that methods can have on research findings. Support Instructors - This program provides instructors with unbeatable resources, including video embedded PowerPoints and the new MyDevelopmentLab that includes cross-cultural videos and MyVirtualTeen, an interactive simulation that allows you to raise a child from birth to age 18. An easy to use Instructor's Manual, a robust test bank, and an online test generator (MyTest) are also available. All of these materials may be packaged with the text upon request. Note: MyDevelopmentLab does not come automatically packaged with this text. To purchase MyDevelopmentLab, please visit: www.mydevelopmentlab.com or you can purchase a ValuePack of the text + MyDevelopmentlab (at no additional cost): ValuePack ISBN-10: 0205911854/ ValuePack ISBN-13: 9780205911851. Click here for a short walkthrough video on MyVirtualTeen! http://www.youtube.com/playlist'list=PL51B144F17A36FF25&feature=plcp

Communities in Action

Communities in Action PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452961
Category : Medical
Languages : en
Pages : 583

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Book Description
In the United States, some populations suffer from far greater disparities in health than others. Those disparities are caused not only by fundamental differences in health status across segments of the population, but also because of inequities in factors that impact health status, so-called determinants of health. Only part of an individual's health status depends on his or her behavior and choice; community-wide problems like poverty, unemployment, poor education, inadequate housing, poor public transportation, interpersonal violence, and decaying neighborhoods also contribute to health inequities, as well as the historic and ongoing interplay of structures, policies, and norms that shape lives. When these factors are not optimal in a community, it does not mean they are intractable: such inequities can be mitigated by social policies that can shape health in powerful ways. Communities in Action: Pathways to Health Equity seeks to delineate the causes of and the solutions to health inequities in the United States. This report focuses on what communities can do to promote health equity, what actions are needed by the many and varied stakeholders that are part of communities or support them, as well as the root causes and structural barriers that need to be overcome.

Musculoskeletal Diseases 2021-2024

Musculoskeletal Diseases 2021-2024 PDF Author: Juerg Hodler
Publisher: Springer Nature
ISBN: 3030712818
Category : Musculoskeletal system
Languages : en
Pages : 293

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Book Description
This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.