Author: Mauricio Tohen
Publisher: Academic Press
ISBN: 0124051766
Category : Medical
Languages : en
Pages : 192
Book Description
Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. - Summarizes common trial design problems and their solutions - Encompasses funding, subject selection, regulatory issues and more - Identifies best practices for definitive and generalizable results - Includes traditional trial designs and novel analytic techniques - Represents academia, industry, regulatory agencies, and advocacy groups
Clinical Trial Design Challenges in Mood Disorders
Author: Mauricio Tohen
Publisher: Academic Press
ISBN: 0124051766
Category : Medical
Languages : en
Pages : 192
Book Description
Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. - Summarizes common trial design problems and their solutions - Encompasses funding, subject selection, regulatory issues and more - Identifies best practices for definitive and generalizable results - Includes traditional trial designs and novel analytic techniques - Represents academia, industry, regulatory agencies, and advocacy groups
Publisher: Academic Press
ISBN: 0124051766
Category : Medical
Languages : en
Pages : 192
Book Description
Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. - Summarizes common trial design problems and their solutions - Encompasses funding, subject selection, regulatory issues and more - Identifies best practices for definitive and generalizable results - Includes traditional trial designs and novel analytic techniques - Represents academia, industry, regulatory agencies, and advocacy groups
Designing Disorder
Author: Richard Sennett
Publisher: Verso Books
ISBN: 1788737830
Category : Political Science
Languages : en
Pages : 161
Book Description
Rethinking the open city Planners, privatisation, and police surveillance are laying siege to urban public spaces. The streets are becoming ever more regimented as life and character are sapped from our cities. What is to be done? Is it possible to maintain the public realm as a flexible space that adapts over time? Can disorder be designed? Fifty years ago, Richard Sennett wrote his groundbreaking work The Uses of Disorder, arguing that the ideal of a planned and ordered city was flawed, likely to produce a fragile, restrictive urban environment. The need for the Open City, the alternative, is now more urgent that ever. In this provocative essay, Pablo Sendra and Richard Sennett propose a reorganisation of how we think and plan the life of our cities. What the authors call 'infrastructures for disorder' combine architecture, politics, urban planning and activism in order to develop places that nurture rather than stifle, bring together rather than divide, remain open to change rather than rapidly stagnate. Designing Disorder is a radical and transformative manifesto for the future of twenty-first-century cities.
Publisher: Verso Books
ISBN: 1788737830
Category : Political Science
Languages : en
Pages : 161
Book Description
Rethinking the open city Planners, privatisation, and police surveillance are laying siege to urban public spaces. The streets are becoming ever more regimented as life and character are sapped from our cities. What is to be done? Is it possible to maintain the public realm as a flexible space that adapts over time? Can disorder be designed? Fifty years ago, Richard Sennett wrote his groundbreaking work The Uses of Disorder, arguing that the ideal of a planned and ordered city was flawed, likely to produce a fragile, restrictive urban environment. The need for the Open City, the alternative, is now more urgent that ever. In this provocative essay, Pablo Sendra and Richard Sennett propose a reorganisation of how we think and plan the life of our cities. What the authors call 'infrastructures for disorder' combine architecture, politics, urban planning and activism in order to develop places that nurture rather than stifle, bring together rather than divide, remain open to change rather than rapidly stagnate. Designing Disorder is a radical and transformative manifesto for the future of twenty-first-century cities.
America Rising
Author: David Felix
Publisher: Routledge
ISBN: 1351532952
Category : Business & Economics
Languages : en
Pages : 345
Book Description
The United States became a great power in the last quarter of the nineteenth century and a superpower during World War II without quite knowing it. Few Americans fully appreciate the fact today. How many people know that in recent years we have had 250,000 troops in 700 bases around the world? Consider our recent history of military operations in the Caribbean, East Asia, the Far East, Middle East, Southeast Asia, Africa, and the Balkans. In America Rising, David Felix attempts to explain how and why America became a superpower by examining the political and economic factors that have driven its ascendence and their relationship throughout history.Felix begins with the dawn of America, showing how America amassed wealth and political power from the start through wars, assertions of economic might, and the creation of a cultural and philosophical base. The nation began with a political order, derived from our British origins, which enabled our pragmatic culture to take advantage of the vast wealth of a near-virgin continent. Political and economic freedom were paired, authority yielding to both freedoms. Our farmers and businessmen were dreamers, manufacturing realities out of those dreams. Felix's account then makes a point of neoclassical economics as an anvil on which to hammer out a sharper sense of the content of our existence.This book, which demonstrates the author's zest for historical analysis and great story-telling ability, points to the central fact of a rising America--the intensely energizing interaction between polity and economy. The United States is the greatest power in world history, but the rise of another great power, China, is beginning to be increasingly apparent. One trusts that, drawing upon its deep resources, America will remember its history and traditions and continue as a superpower.
Publisher: Routledge
ISBN: 1351532952
Category : Business & Economics
Languages : en
Pages : 345
Book Description
The United States became a great power in the last quarter of the nineteenth century and a superpower during World War II without quite knowing it. Few Americans fully appreciate the fact today. How many people know that in recent years we have had 250,000 troops in 700 bases around the world? Consider our recent history of military operations in the Caribbean, East Asia, the Far East, Middle East, Southeast Asia, Africa, and the Balkans. In America Rising, David Felix attempts to explain how and why America became a superpower by examining the political and economic factors that have driven its ascendence and their relationship throughout history.Felix begins with the dawn of America, showing how America amassed wealth and political power from the start through wars, assertions of economic might, and the creation of a cultural and philosophical base. The nation began with a political order, derived from our British origins, which enabled our pragmatic culture to take advantage of the vast wealth of a near-virgin continent. Political and economic freedom were paired, authority yielding to both freedoms. Our farmers and businessmen were dreamers, manufacturing realities out of those dreams. Felix's account then makes a point of neoclassical economics as an anvil on which to hammer out a sharper sense of the content of our existence.This book, which demonstrates the author's zest for historical analysis and great story-telling ability, points to the central fact of a rising America--the intensely energizing interaction between polity and economy. The United States is the greatest power in world history, but the rise of another great power, China, is beginning to be increasingly apparent. One trusts that, drawing upon its deep resources, America will remember its history and traditions and continue as a superpower.
Ordering Disorder
Author: Khoi Vinh
Publisher: Pearson Education
ISBN: 0321713737
Category : Computers
Languages : en
Pages : 307
Book Description
The grid has long been an invaluable tool for creating order out of chaos for designers of all kinds—from city planners to architects to typesetters and graphic artists. In recent years, web designers, too, have come to discover the remarkable power that grid-based design can afford in creating intuitive, immersive, and beautiful user experiences. Ordering Disorder delivers a definitive take on grids and the Web. It provides both the big ideas and the brass-tacks techniques of grid-based design. Readers are sure to come away with a keen understanding of the power of grids, as well as the design tools needed to implement them for the World Wide Web. Khoi Vinh is internationally recognized for bringing the tried-and-true principles of the typographic grid to the World Wide Web. He is the former Design Director for NYTimes.com, where he consolidated his reputation for superior user experience design. He writes and lectures widely on design, technology, and culture, and has published the popular blog Subtraction.com for over a decade. More information at grids.subtraction.com
Publisher: Pearson Education
ISBN: 0321713737
Category : Computers
Languages : en
Pages : 307
Book Description
The grid has long been an invaluable tool for creating order out of chaos for designers of all kinds—from city planners to architects to typesetters and graphic artists. In recent years, web designers, too, have come to discover the remarkable power that grid-based design can afford in creating intuitive, immersive, and beautiful user experiences. Ordering Disorder delivers a definitive take on grids and the Web. It provides both the big ideas and the brass-tacks techniques of grid-based design. Readers are sure to come away with a keen understanding of the power of grids, as well as the design tools needed to implement them for the World Wide Web. Khoi Vinh is internationally recognized for bringing the tried-and-true principles of the typographic grid to the World Wide Web. He is the former Design Director for NYTimes.com, where he consolidated his reputation for superior user experience design. He writes and lectures widely on design, technology, and culture, and has published the popular blog Subtraction.com for over a decade. More information at grids.subtraction.com
Design Discourse
Author: Victor Margolin
Publisher: University of Chicago Press
ISBN: 0226505146
Category : Art
Languages : en
Pages : 302
Book Description
The editor has gathered together a body of writing in the emerging field of design studies. The contributors argue in different ways for a rethinking of design in the light of its cultural significance and its powerful position in today's society. The collection begins with a discussion of the various expressions of opposition to the modernists' purist approach toward design. Drawing on postmodernist theory and other critical strategies, the writers examine the relations among design, technology, and social organization to show how design has become a complex and multidisciplinary activity. The second section provides examples of new methods of interpreting and analysing design, ranging from rhetoric and semiotics to phenomenology, demonstrating how meaning is created visually. A final section related to design history shifts its emphasis to ideological frameworks such as capitalism and patriarchy that establish boundaries for the production and use of design.
Publisher: University of Chicago Press
ISBN: 0226505146
Category : Art
Languages : en
Pages : 302
Book Description
The editor has gathered together a body of writing in the emerging field of design studies. The contributors argue in different ways for a rethinking of design in the light of its cultural significance and its powerful position in today's society. The collection begins with a discussion of the various expressions of opposition to the modernists' purist approach toward design. Drawing on postmodernist theory and other critical strategies, the writers examine the relations among design, technology, and social organization to show how design has become a complex and multidisciplinary activity. The second section provides examples of new methods of interpreting and analysing design, ranging from rhetoric and semiotics to phenomenology, demonstrating how meaning is created visually. A final section related to design history shifts its emphasis to ideological frameworks such as capitalism and patriarchy that establish boundaries for the production and use of design.
Trauma and Posttraumatic Stress Disorder
Author: Evelyn J. Bromet
Publisher: Cambridge University Press
ISBN: 1107059690
Category : Medical
Languages : en
Pages : 359
Book Description
The first systematic analysis of the rates, risk factors, consequences and global burden of trauma and PTSD across the globe.
Publisher: Cambridge University Press
ISBN: 1107059690
Category : Medical
Languages : en
Pages : 359
Book Description
The first systematic analysis of the rates, risk factors, consequences and global burden of trauma and PTSD across the globe.
Communication Disorders in Multicultural Populations
Author: Dolores E. Battle
Publisher: Elsevier Health Sciences
ISBN: 0323087124
Category : Medical
Languages : en
Pages : 337
Book Description
Written by some of the top researchers and clinicians in the field, Communication Disorders in Multicultural Populations, 4th Edition offers an in-depth look at the major cultural groups in the U.S. and the issues concerning their communication development, common disorders, and treatment options. This fourth edition features a wealth of updates and new features — including the latest research and added coverage of communication issues in countries such as Australia, China, Canada, and Brazil — to give speech-language pathology students and speech-language pathologists a balanced and global perspective on the most topical multicultural communication issues of today. - Comprehensive coverage focuses on a wide variety of cultural and age populations. - Cutting-edge research and data offer up-to-date discussions based on the latest studies in multiculturalism as it relates to the SLP and AuD professions. - Diverse panel of expert authors include some of the top researchers and clinicians in the field. - Additional resources provide a focused listing of print and electronic sources at the end of each chapter to support more in-depth study of a particular subject. - Chapter on international perspectives tackles issues in countries such as Australia, Canada, China, and Brazil to give you a more global understanding of communication disorders. - The latest statistics from the 2010 U.S. Census report offers the most current data available. - Increased content on older adults covers the multicultural issues, voice disorders, and neurogenic disorders particular to this important demographic. - Case studies give you practice solving realistic clinical problems. - Chapter overview and conclusion outline the key information in each chapter and serve as a checklist for content mastery.
Publisher: Elsevier Health Sciences
ISBN: 0323087124
Category : Medical
Languages : en
Pages : 337
Book Description
Written by some of the top researchers and clinicians in the field, Communication Disorders in Multicultural Populations, 4th Edition offers an in-depth look at the major cultural groups in the U.S. and the issues concerning their communication development, common disorders, and treatment options. This fourth edition features a wealth of updates and new features — including the latest research and added coverage of communication issues in countries such as Australia, China, Canada, and Brazil — to give speech-language pathology students and speech-language pathologists a balanced and global perspective on the most topical multicultural communication issues of today. - Comprehensive coverage focuses on a wide variety of cultural and age populations. - Cutting-edge research and data offer up-to-date discussions based on the latest studies in multiculturalism as it relates to the SLP and AuD professions. - Diverse panel of expert authors include some of the top researchers and clinicians in the field. - Additional resources provide a focused listing of print and electronic sources at the end of each chapter to support more in-depth study of a particular subject. - Chapter on international perspectives tackles issues in countries such as Australia, Canada, China, and Brazil to give you a more global understanding of communication disorders. - The latest statistics from the 2010 U.S. Census report offers the most current data available. - Increased content on older adults covers the multicultural issues, voice disorders, and neurogenic disorders particular to this important demographic. - Case studies give you practice solving realistic clinical problems. - Chapter overview and conclusion outline the key information in each chapter and serve as a checklist for content mastery.
Design and Analysis in Educational Research
Author: Kamden K. Strunk
Publisher: Routledge
ISBN: 0429780060
Category : Education
Languages : en
Pages : 305
Book Description
NEW: updated eResources, 'Case Studies for Teaching on Race, Racism and Black Lives Matter.' Please see Support Material tab to download the new resources. This book presents an integrated approach to learning about research design alongside statistical analysis concepts. Strunk and Mwavita maintain a focus on applied educational research throughout the text, with practical tips and advice on how to do high-quality quantitative research. Design and Analysis in Educational Research teaches research design (including epistemology, research ethics, forming research questions, quantitative design, sampling methodologies, and design assumptions) and introductory statistical concepts (including descriptive statistics, probability theory, sampling distributions), basic statistical tests (like z and t), and ANOVA designs, including more advanced designs like the factorial ANOVA and mixed ANOVA, using SPSS for analysis. Designed specifically for an introductory graduate course in research design and statistical analysis, the book takes students through principles by presenting case studies, describing the research design principles at play in each study, and then asking students to walk through the process of analyzing data that reproduce the published results. An online eResource is also available with data sets. This textbook is tailor-made for first-level doctoral courses in research design and analysis, and will also be of interest to graduate students in education and educational research.
Publisher: Routledge
ISBN: 0429780060
Category : Education
Languages : en
Pages : 305
Book Description
NEW: updated eResources, 'Case Studies for Teaching on Race, Racism and Black Lives Matter.' Please see Support Material tab to download the new resources. This book presents an integrated approach to learning about research design alongside statistical analysis concepts. Strunk and Mwavita maintain a focus on applied educational research throughout the text, with practical tips and advice on how to do high-quality quantitative research. Design and Analysis in Educational Research teaches research design (including epistemology, research ethics, forming research questions, quantitative design, sampling methodologies, and design assumptions) and introductory statistical concepts (including descriptive statistics, probability theory, sampling distributions), basic statistical tests (like z and t), and ANOVA designs, including more advanced designs like the factorial ANOVA and mixed ANOVA, using SPSS for analysis. Designed specifically for an introductory graduate course in research design and statistical analysis, the book takes students through principles by presenting case studies, describing the research design principles at play in each study, and then asking students to walk through the process of analyzing data that reproduce the published results. An online eResource is also available with data sets. This textbook is tailor-made for first-level doctoral courses in research design and analysis, and will also be of interest to graduate students in education and educational research.
Behavioral Principles in Communicative Disorders
Author: Christine A. Maul
Publisher: Plural Publishing
ISBN: 1597569534
Category : Medical
Languages : en
Pages : 305
Book Description
Behavioral Principles in Communicative Disorders: Applications to Assessment and Treatment examines the basic principles of the science of behaviorism and applies those principles to the assessment and treatment of communicative disorders. It begins with the history and basic principles of behaviorism, as well as a chapter examining Skinner's (1957) concept of verbal behavior and functional units of verbal behavior. The text then discusses functional behavior assessment, the formulation of operationally defined target behaviors, discrete trial treatment procedures, and various techniques for increasing desirable behaviors and decreasing undesirable behaviors. The concluding chapters describe single-case research designs that support the efficacy of behavioral principles and address ethical questions and historic controversies surrounding the application of those principles. Speech-language pathologists (SLPs) seek to change communicative behaviors in the clients they serve; the principles of behavioral science have many applications to the assessment and treatment of communicative disorders. There is a vast body of evidence indicating the efficacy of behavioral approaches in behavior modification, and SLPs have been tasked by their professional associations to employ evidence-based practices. Also, there is an appreciation for the usefulness of behavioral principles in treating clients with very severe communicative disorders, such as autism, apraxia, and dysfluency. This is evidenced by the development of the field of applied behavior analysis and the growing numbers of board certified behavior analysts (BCBA), with whom SLPs may be called upon to collaborate. Behavioral Principles in Communicative Disorders is primarily designed for practicing speech-language pathologists looking for detailed descriptions of evidence-based treatment procedures, as well as professors and students in university programs in communicative disorders. However, professionals in other fields, such as applied behavior analysis and special education, will also find this to be a highly useful text.
Publisher: Plural Publishing
ISBN: 1597569534
Category : Medical
Languages : en
Pages : 305
Book Description
Behavioral Principles in Communicative Disorders: Applications to Assessment and Treatment examines the basic principles of the science of behaviorism and applies those principles to the assessment and treatment of communicative disorders. It begins with the history and basic principles of behaviorism, as well as a chapter examining Skinner's (1957) concept of verbal behavior and functional units of verbal behavior. The text then discusses functional behavior assessment, the formulation of operationally defined target behaviors, discrete trial treatment procedures, and various techniques for increasing desirable behaviors and decreasing undesirable behaviors. The concluding chapters describe single-case research designs that support the efficacy of behavioral principles and address ethical questions and historic controversies surrounding the application of those principles. Speech-language pathologists (SLPs) seek to change communicative behaviors in the clients they serve; the principles of behavioral science have many applications to the assessment and treatment of communicative disorders. There is a vast body of evidence indicating the efficacy of behavioral approaches in behavior modification, and SLPs have been tasked by their professional associations to employ evidence-based practices. Also, there is an appreciation for the usefulness of behavioral principles in treating clients with very severe communicative disorders, such as autism, apraxia, and dysfluency. This is evidenced by the development of the field of applied behavior analysis and the growing numbers of board certified behavior analysts (BCBA), with whom SLPs may be called upon to collaborate. Behavioral Principles in Communicative Disorders is primarily designed for practicing speech-language pathologists looking for detailed descriptions of evidence-based treatment procedures, as well as professors and students in university programs in communicative disorders. However, professionals in other fields, such as applied behavior analysis and special education, will also find this to be a highly useful text.
Clinical Research in Communication Disorders
Author: M. N. Hegde
Publisher: Plural Publishing
ISBN: 1635502004
Category : Medical
Languages : en
Pages : 541
Book Description
This thoroughly updated fourth edition of Clinical Research in Communication Disorders: Principles and Strategies remains an instrumental resource for courses on research methods and design in communication disorders. The book is separated into three key sections: science and the scientific methods, clinical research designs, and doing, reporting, and evaluating research. Together, these sections provide thorough coverage of both the single-subject and group design strategies along with issues of measurement; philosophy of science; ethics of research; and planning, conducting, and reporting research. Instructors and students in communication sciences and disorders will appreciate the text's comprehensive coverage of scientific methods, group and single-subject research designs, report writing, and ethics of research in a single source. New to the Fourth EditionNew coauthor, Anthony P. Salvatore, PhDA new chapter on statistical analysis of research data, including several statistical techniques for single-subject research data, meta-analysis of both group and single-subject studiesUpdated criteria for visual analysis of single-subject research dataNew sections on translational research, qualitative research, and mixed methods researchDescriptions of additional research designs not included in the previous edition (e.g., the regression discontinuity design)Updated information on research ethics and review of fraudulent biomedical researchWeb-based sources that monitor research fraud and recalled studiesUpdated and expanded references throughoutKey FeaturesChapter outlines open each chapter and provide a summary of the key topicsChapter summaries recap key points in an easy-to-read bulleted formatEnd-of-chapter study guides allow readers to test their knowledgeBolded key terms throughoutDisclaimer: Please note that ancillary content (such as documents, audio, and video, etc.) may not be included as published in the original print version of this book.
Publisher: Plural Publishing
ISBN: 1635502004
Category : Medical
Languages : en
Pages : 541
Book Description
This thoroughly updated fourth edition of Clinical Research in Communication Disorders: Principles and Strategies remains an instrumental resource for courses on research methods and design in communication disorders. The book is separated into three key sections: science and the scientific methods, clinical research designs, and doing, reporting, and evaluating research. Together, these sections provide thorough coverage of both the single-subject and group design strategies along with issues of measurement; philosophy of science; ethics of research; and planning, conducting, and reporting research. Instructors and students in communication sciences and disorders will appreciate the text's comprehensive coverage of scientific methods, group and single-subject research designs, report writing, and ethics of research in a single source. New to the Fourth EditionNew coauthor, Anthony P. Salvatore, PhDA new chapter on statistical analysis of research data, including several statistical techniques for single-subject research data, meta-analysis of both group and single-subject studiesUpdated criteria for visual analysis of single-subject research dataNew sections on translational research, qualitative research, and mixed methods researchDescriptions of additional research designs not included in the previous edition (e.g., the regression discontinuity design)Updated information on research ethics and review of fraudulent biomedical researchWeb-based sources that monitor research fraud and recalled studiesUpdated and expanded references throughoutKey FeaturesChapter outlines open each chapter and provide a summary of the key topicsChapter summaries recap key points in an easy-to-read bulleted formatEnd-of-chapter study guides allow readers to test their knowledgeBolded key terms throughoutDisclaimer: Please note that ancillary content (such as documents, audio, and video, etc.) may not be included as published in the original print version of this book.