Design and implementation of a CMOS interface for non-invase optical biosensors

Design and implementation of a CMOS interface for non-invase optical biosensors PDF Author: Eduardo Andrés Barredo Ochoa
Publisher:
ISBN:
Category :
Languages : es
Pages :

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Book Description
In this thesis, I propose an optoelectronic interface as those required in non-invasive micro sensors. The interface was implemented on a 0.35u.m CMOS technology and consists of a photodiode to capture and transform light into a current, and an amplifier to convert this current into a voltage level. I have designed three different photodiodes. Because of their structures, they are called p+/nwell, n+/p-substrate, nwell/p-substrate photodiodes. Additionally, I have implemented the spatially modulated technique in order to increase the photodiodes bandwidth. The required ring to avoid interference and to protect the input pads had also been incorporated in the layout. I have reviewed mathematical approximations that describe the photocurrent in the frequency domain. These approximations could be used in later studies aimed to characterize photodiode. Finally, the amplifier consists on a current to voltage conversion, a bandwidth expansion module and a voltage amplifier. The amplifier has showed a transimpedance of 47 ^/mj[, a frequency bandwidth of 852MHz and a gain-bandwidth of 2GHz.

Bio/CMOS Interfaces and Co-Design

Bio/CMOS Interfaces and Co-Design PDF Author: Sandro Carrara
Publisher: Springer
ISBN: 9781493951222
Category :
Languages : en
Pages : 274

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Book Description
Developments in 3-D circuit design and nanotechnology have boosted interdisciplinary approaches to engineering Bio/CMOS interfaces. Here is an invaluable guide to the state of the art in this fast-moving field where chips now feature integrated biomolecules.

Biosensors and CMOS Interface Circuits

Biosensors and CMOS Interface Circuits PDF Author: Sahil S. Shah
Publisher:
ISBN:
Category : Biosensors
Languages : en
Pages : 75

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Book Description
Analysing and measuring of biological or biochemical processes are of utmost importance for medical, biological and biotechnological applications. Point of care diagnostic system, composing of biosensors, have promising applications for providing cheap, accurate and portable diagnosis. Owing to these expanding medical applications and advances made by semiconductor industry biosensors have seen a tremendous growth in the past few decades. Also emergence of microfluidics and non-invasive biosensing applications are other marker propellers. Analyzing biological signals using transducers is difficult due to the challenges in interfacing an electronic system to the biological environment. Detection limit, detection time, dynamic range, specificity to the analyte, sensitivity and reliability of these devices are some of the challenges in developing and integrating these devices. Significant amount of research in the field of biosensors has been focused on improving the design, fabrication process and their integration with microfluidics to address these challenges. This work presents new techniques, design and systems to improve the interface between the electronic system and the biological environment. This dissertation uses CMOS circuit design to improve the reliability of these devices. Also this work addresses the challenges in designing the electronic system used for processing the output of the transducer, which converts biological signal into electronic signal.

Semiconductor Gas Sensors

Semiconductor Gas Sensors PDF Author: Raivo Jaaniso
Publisher: Woodhead Publishing
ISBN: 0081025602
Category : Technology & Engineering
Languages : en
Pages : 512

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Book Description
Semiconductor Gas Sensors, Second Edition, summarizes recent research on basic principles, new materials and emerging technologies in this essential field. Chapters cover the foundation of the underlying principles and sensing mechanisms of gas sensors, include expanded content on gas sensing characteristics, such as response, sensitivity and cross-sensitivity, present an overview of the nanomaterials utilized for gas sensing, and review the latest applications for semiconductor gas sensors, including environmental monitoring, indoor monitoring, medical applications, CMOS integration and chemical warfare agents. This second edition has been completely updated, thus ensuring it reflects current literature and the latest materials systems and applications. - Includes an overview of key applications, with new chapters on indoor monitoring and medical applications - Reviews developments in gas sensors and sensing methods, including an expanded section on gas sensor theory - Discusses the use of nanomaterials in gas sensing, with new chapters on single-layer graphene sensors, graphene oxide sensors, printed sensors, and much more

Advanced Biosensors for Health Care Applications

Advanced Biosensors for Health Care Applications PDF Author: Raju Khan
Publisher: Elsevier
ISBN: 0128165227
Category : Technology & Engineering
Languages : en
Pages : 433

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Book Description
Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. - Describes advanced nanomaterials for biosensor applications - Relates the properties of available nanomaterials to specific biomarkers applications - Includes diagnosis and electrochemical studies based on biosensors - Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies - Describes novel strategies for developing a new class of assay systems to retrieve the desired health information

NanoBiosensing

NanoBiosensing PDF Author: Huangxian Ju
Publisher: Springer Science & Business Media
ISBN: 1441996222
Category : Technology & Engineering
Languages : en
Pages : 596

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Book Description
This book will cover the full scope of nanobiosensing, which combines the newest research results in the cross-disciplines of chemistry, biology, and materials science with biosensing and bioanalysis to develop novel detection principles, sensing mechanisms, and device engineering methods. It not only covers the important types of nanomaterials for biosensing applications, including carbon nanotubes, carbon nanofiber, quantum dots, fullerenes, fluorescent and biological molecules, etc., but also illustrates a wide range of sensing principles, including electrochemical detection, fluorescence, chemiluminesence, antibody-antigen interactions, and magnetic detection. The book details novel developments in the methodology and devices of biosensing and bioanalysis combined with nanoscience and nanotechnology, as well as their applications in biomedicine and environmental monitoring. Furthermore, the reported works on the application and biofunction of nanoparticles have attracted extensive attention and interest, thus they are of particular interest to readers. The reader will obtain a rich survey of nanobiosensing technology, including the principles and application of biosensing, the design and biofunctionalization of bionanomaterials, as well as the methodology to develop biosensing devices and bioanalytical systems.

Low-power Wearable Healthcare Sensors

Low-power Wearable Healthcare Sensors PDF Author: R. Simon Sherratt
Publisher: MDPI
ISBN: 3039364790
Category : Science
Languages : en
Pages : 146

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Book Description
Advances in technology have produced a range of on-body sensors and smartwatches that can be used to monitor a wearer’s health with the objective to keep the user healthy. However, the real potential of such devices not only lies in monitoring but also in interactive communication with expert-system-based cloud services to offer personalized and real-time healthcare advice that will enable the user to manage their health and, over time, to reduce expensive hospital admissions. To meet this goal, the research challenges for the next generation of wearable healthcare devices include the need to offer a wide range of sensing, computing, communication, and human–computer interaction methods, all within a tiny device with limited resources and electrical power. This Special Issue presents a collection of six papers on a wide range of research developments that highlight the specific challenges in creating the next generation of low-power wearable healthcare sensors.

Wearable Bioelectronics

Wearable Bioelectronics PDF Author: Anthony P.F. Turner
Publisher: Elsevier
ISBN: 0081024088
Category : Technology & Engineering
Languages : en
Pages : 240

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Book Description
Wearable Bioelectronics presents the latest on physical and (bio)chemical sensing for wearable electronics. It covers the miniaturization of bioelectrodes and high-throughput biosensing platforms while also presenting a systemic approach for the development of electrochemical biosensors and bioelectronics for biomedical applications. The book addresses the fundamentals, materials, processes and devices for wearable bioelectronics, showcasing key applications, including device fabrication, manufacturing, and healthcare applications. Topics covered include self-powering wearable bioelectronics, electrochemical transducers, textile-based biosensors, epidermal electronics and other exciting applications. - Includes comprehensive and systematic coverage of the most exciting and promising bioelectronics, processes for their fabrication, and their applications in healthcare - Reviews innovative applications, such as self-powering wearable bioelectronics, electrochemical transducers, textile-based biosensors and electronic skin - Examines and discusses the future of wearable bioelectronics - Addresses the wearable electronics market as a development of the healthcare industry

Bio/CMOS Interfaces and Co-Design

Bio/CMOS Interfaces and Co-Design PDF Author: Sandro Carrara
Publisher: Springer Science & Business Media
ISBN: 1461446902
Category : Technology & Engineering
Languages : en
Pages : 266

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Book Description
The application of CMOS circuits and ASIC VLSI systems to problems in medicine and system biology has led to the emergence of Bio/CMOS Interfaces and Co-Design as an exciting and rapidly growing area of research. The mutual inter-relationships between VLSI-CMOS design and the biophysics of molecules interfacing with silicon and/or onto metals has led to the emergence of the interdisciplinary engineering approach to Bio/CMOS interfaces. This new approach, facilitated by 3D circuit design and nanotechnology, has resulted in new concepts and applications for VLSI systems in the bio-world. This book offers an invaluable reference to the state-of-the-art in Bio/CMOS interfaces. It describes leading-edge research in the field of CMOS design and VLSI development for applications requiring integration of biological molecules onto the chip. It provides multidisciplinary content ranging from biochemistry to CMOS design in order to address Bio/CMOS interface co-design in bio-sensing applications.

Electrochemical Biosensors

Electrochemical Biosensors PDF Author: Serge Cosnier
Publisher: CRC Press
ISBN: 9814411477
Category : Science
Languages : en
Pages : 405

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Book Description
Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy