Demystifying Depression: Complete Spectrum - ECAB

Demystifying Depression: Complete Spectrum - ECAB PDF Author: Nimesh G Desai
Publisher: Elsevier Health Sciences
ISBN: 8131239497
Category : Medical
Languages : en
Pages : 108

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Book Description
Demystifying Depression: Complete Spectrum - ECAB

Demystifying Depression: Complete Spectrum - ECAB

Demystifying Depression: Complete Spectrum - ECAB PDF Author: Nimesh G Desai
Publisher: Elsevier Health Sciences
ISBN: 8131239497
Category : Medical
Languages : en
Pages : 108

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Book Description
Demystifying Depression: Complete Spectrum - ECAB

Demystifying Depression

Demystifying Depression PDF Author: Nimesh G. Desai
Publisher:
ISBN: 9788131232866
Category :
Languages : en
Pages :

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Book Description
Demystifying Depression: Complete Spectrum - ECAB

The Roads In-between

The Roads In-between PDF Author: Johan Normark
Publisher: Goteborg University
ISBN:
Category : Agent (Philosophy)
Languages : en
Pages : 358

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Book Description


Through the Prism of Slavery

Through the Prism of Slavery PDF Author: Dale W. Tomich
Publisher: Rowman & Littlefield
ISBN: 9780742529397
Category : Business & Economics
Languages : en
Pages : 234

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Book Description
In this thoughtful book, Dale W. Tomich explores the contested relationship between slavery and capitalism. Tracing slavery's integral role in the formation of a capitalist world economy, he reinterprets the development of the world economy through the "prism of slavery." Through a sustained critique of Marxism, world-systems theory, and new economic history, Tomich develops an original conceptual framework for answering theoretical and historical questions about the nexus between slavery and the world economy. The author explores how particular slave systems were affected by their integration into the world market, the international division of labor, and the interstate system. He further examines the ways that the particular "local" histories of such slave regimes illuminate processes of world economic change. His deft use of specific New World examples of slave production as local sites of global transformation highlights the influence of specific geographies and local agency in shaping different slave zones. Tomich's cogent analysis of the struggles over the organization of work and labor discipline in the French West Indian colony of Martinique vividly illustrates the ways that day-to-day resistance altered the relationship between master and slave, precipitated crises in sugar cultivation, and created the local conditions for the transition to a post-slavery economy and society.

The Picture of Dorian Gray

The Picture of Dorian Gray PDF Author: Oscar Wilde
Publisher: Oldcastle Books
ISBN: 1843441853
Category : Fiction
Languages : en
Pages : 216

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Book Description
Hey Girl... I'd sell my soul for you Dorian Gray might be as pretty as a picture, but he's paid a devilishly high price for it. He'll stay drop-dead gorgeous, but there's something nasty festering in the attic...

Advances in Medicinal Chemistry

Advances in Medicinal Chemistry PDF Author: B.E. Maryanoff
Publisher: Elsevier
ISBN: 0080526373
Category : Science
Languages : en
Pages : 338

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Book Description
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.

Brandishing Cyberattack Capabilities

Brandishing Cyberattack Capabilities PDF Author: Martin C. Libicki
Publisher: Rand Corporation
ISBN: 0833080059
Category : Computers
Languages : en
Pages : 115

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Book Description
Deterrence is possible only when others have at least a good idea of possible U.S. military reprisals, but cyberattack capabilities resist such demonstration. This report explores ways they can be and under what circumstances, then goes on to examine the difficulties and the drawbacks. Such "brandishing" is no panacea and could even backfire if misinterpreted. Its success also relies on the strength of other elements of the deterrence posture.

Diversity-Oriented Synthesis

Diversity-Oriented Synthesis PDF Author: Andrea Trabocchi
Publisher: John Wiley & Sons
ISBN: 1118618149
Category : Science
Languages : en
Pages : 550

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Book Description
Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

Russian Grand Strategy

Russian Grand Strategy PDF Author: Samuel Charap
Publisher: Rand Corporation
ISBN: 1977407544
Category : History
Languages : en
Pages : 246

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Book Description
Understanding Russia’s grand strategy can help U.S. decisionmakers assess the depth and nature of potential conflicts between Russia and the United States and avoid strategic surprise by better-anticipating Moscow’s actions and reactions. The authors of this report review Russia’s declared grand strategy, evaluate the extent to which Russian behavior is consistent with stated strategy, and outline implications for the United States.

Structure-based Drug Discovery

Structure-based Drug Discovery PDF Author: Harren Jhoti
Publisher: Springer Science & Business Media
ISBN: 1402044070
Category : Science
Languages : en
Pages : 255

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Book Description
This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.