Author: Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 248
Book Description
NIDA Research Monograph
Author: Molecular Approaches to Drug Abuse Research
Author: Mars Geological Enigmas
Author: Richard SoarePublisher: Elsevier
ISBN: 0128202467
Category : Science
Languages : en
Pages : 556
Book Description
Mars Geological Enigmas: From the Late Noachian Epoch to the Present Day presents outstanding questions on the geology of Mars and divergent viewpoints based on varying interpretations and analyses. The result is a robust and comprehensive discussion that provides opportunities for planetary scientists to develop their own opinions and ways forward. Each theme opens with an introduction that includes background on the topic and lays out questions to be addressed. Alternate perspectives are covered for each topic, including methods, observations, analyses, and in-depth discussion of the conclusions. Chapters within each theme reference each other to facilitate comparison and deeper understanding of divergent opinions. Offers a transchronological view of the geological history of Mars, addressing thematic questions from a broad temporal perspective Discusses outstanding questions on Mars from diverging perspectives Includes key questions and answers, as well as a look ahead to which puzzles remain to be solved
The Physiography of the Southern Wasatch Mountains and the Adjacent Valley Lands with Especial Reference to the Origin of Topographic Forms
Author: Fred Earle BussPublisher:
ISBN:
Category :
Languages : en
Pages : 256
Book Description
U.S. Geological Survey Professional Paper
Author: Geological Survey Professional Paper
Author: Transcriptional and Chromatin Regulation in Adaptive and Innate Immune Cells
Author: Keiko OzatoPublisher: Frontiers Media SA
ISBN: 2889637239
Category :
Languages : en
Pages : 149
Book Description
Transcription depends on an ordered sequence of events, starting with (i) setting of the enhancer and chromatin environment, (ii) assembly of DNA binding and general transcription factors, (iii) initiation, elongation, processing of mRNA and termination, followed by (iv) creation of epigenetic marks and memory formation. Highlighting the importance of these activities, more than 10% total genes are dedicated to regulating transcriptional mechanisms. This area of research is highly active and new insights are continuously being added to our knowledge. Cells of the immune system have unique features of gene regulation to support diverse tasks required for innate and adaptive immunity. Innate immunity involves the recognition of external infectious and noxious agents as well as internal cancer cell components, and the elimination of these agents by non-specific mechanisms. Adaptive immunity involves gene rearrangement to achieve highly specific T and B cell responses, imparting the capability of self and non-self discrimination. This requires transcription and epigenetic regulation. Adaptive immunity also employs epigenetic memory, enabling recapitulation of prior transcription. Recent advances in nuclear architecture, chromatin structure, and transcriptional regulation have provided new insights into immune responses. The increased understanding of these molecular mechanisms is now affording opportunities to improve therapeutic strategies for various diseases.
Annual Report
Author: New York State MuseumPublisher:
ISBN:
Category : Museums
Languages : en
Pages : 610
Book Description
"These reports are made up of the reports of the director, geologist, paleontologist, botanist and entomologist, and museum Bulletins and Memoirs, issued as advance sections of the reports." N.Y. State Museum. Bulletin 66, p. 241.
Geology of the Remsen Quadrangle
Author: William John MillerPublisher:
ISBN:
Category : Geology
Languages : en
Pages : 794
Book Description
Web Dynamics
Author: Mark LevenePublisher: Springer Science & Business Media
ISBN: 3662108747
Category : Computers
Languages : en
Pages : 457
Book Description
The World Wide Web has become a ubiquitous global tool, used for finding infor mation, communicating ideas, carrying out distributed computation and conducting business, learning and science. The Web is highly dynamic in both the content and quantity of the information that it encompasses. In order to fully exploit its enormous potential as a global repository of information, we need to understand how its size, topology and content are evolv ing. This then allows the development of new techniques for locating and retrieving information that are better able to adapt and scale to its change and growth. The Web's users are highly diverse and can access the Web from a variety of devices and interfaces, at different places and times, and for varying purposes. We thus also need techniques for personalising the presentation and content of Web based information depending on how it is being accessed and on the specific user's requirements. As well as being accessed by human users, the Web is also accessed by appli cations. New applications in areas such as e-business, sensor networks, and mobile and ubiquitous computing need to be able to detect and react quickly to events and changes in Web-based information. Traditional approaches using query-based 'pull' of information to find out if events or changes of interest have occurred may not be able to scale to the quantity and frequency of events and changes being generated, and new 'push' -based techniques are needed.
