Author: Lynn Helena Caporale
Publisher: Darwin in the Genome
ISBN: 0071378227
Category : Business & Economics
Languages : en
Pages : 259
Book Description
Publisher Description
Darwin in the Genome
Author: Lynn Helena Caporale
Publisher: Darwin in the Genome
ISBN: 0071378227
Category : Business & Economics
Languages : en
Pages : 259
Book Description
Publisher Description
Publisher: Darwin in the Genome
ISBN: 0071378227
Category : Business & Economics
Languages : en
Pages : 259
Book Description
Publisher Description
The Selfish Gene
Author: Richard Dawkins
Publisher: Oxford University Press, USA
ISBN: 9780192860927
Category : Medical
Languages : en
Pages : 372
Book Description
Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Publisher: Oxford University Press, USA
ISBN: 9780192860927
Category : Medical
Languages : en
Pages : 372
Book Description
Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Evolution
Author: James Alan Shapiro
Publisher: Pearson Education
ISBN: 0132780933
Category : Juvenile Nonfiction
Languages : en
Pages : 273
Book Description
This book proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents an alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and saltationism, and points toward an emerging synthesis of physical, information, and biological sciences.
Publisher: Pearson Education
ISBN: 0132780933
Category : Juvenile Nonfiction
Languages : en
Pages : 273
Book Description
This book proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents an alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and saltationism, and points toward an emerging synthesis of physical, information, and biological sciences.
Human Evolution Beyond Biology and Culture
Author: Jeroen C. J. M. van den Bergh
Publisher: Cambridge University Press
ISBN: 1108470971
Category : Nature
Languages : en
Pages : 575
Book Description
A complete account of evolutionary thought in the social, environmental and policy sciences, creating bridges with biology.
Publisher: Cambridge University Press
ISBN: 1108470971
Category : Nature
Languages : en
Pages : 575
Book Description
A complete account of evolutionary thought in the social, environmental and policy sciences, creating bridges with biology.
Molecular and Genome Evolution
Author: Dan Graur
Publisher: Sinauer
ISBN: 9781605354699
Category : Science
Languages : en
Pages : 0
Book Description
This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.
Publisher: Sinauer
ISBN: 9781605354699
Category : Science
Languages : en
Pages : 0
Book Description
This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.
Molecular Strategies in Biological Evolution
Author: Lynn Helena Caporale
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 462
Book Description
This reference work, the result of a conference co-chaired with Nobel laureate Werner Arber, addresses the molecular strategies by which lineages of organisms respond to challenges and opportunities in their environment. It explores the notion that organisms have evolved the ability to modulate the rate, location and extent of genetic variation. Jumps in efficiency, made possible by development of novel efficient evolutionary strategies, could fuel rapid, saltatory expansion of species into novel niches as each innovation evolves. An up-to-date assessment is provided on biochemical mechanisms available to modulate the rate of genetic change at specific sites within a genome, the induction in certain environments of enzymes with altered sequence-dependent recombination, mismatch repair and/or replication fidelity, and statistical evidence for nonrandom genetic events. This discussion of genomic strategies for evolution has profound implications for basic biology and evolutionary theory. The subjects explored are important ones in understanding inherited diseases, tumor progression and the challenges posed by pathogenic organisms.
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 462
Book Description
This reference work, the result of a conference co-chaired with Nobel laureate Werner Arber, addresses the molecular strategies by which lineages of organisms respond to challenges and opportunities in their environment. It explores the notion that organisms have evolved the ability to modulate the rate, location and extent of genetic variation. Jumps in efficiency, made possible by development of novel efficient evolutionary strategies, could fuel rapid, saltatory expansion of species into novel niches as each innovation evolves. An up-to-date assessment is provided on biochemical mechanisms available to modulate the rate of genetic change at specific sites within a genome, the induction in certain environments of enzymes with altered sequence-dependent recombination, mismatch repair and/or replication fidelity, and statistical evidence for nonrandom genetic events. This discussion of genomic strategies for evolution has profound implications for basic biology and evolutionary theory. The subjects explored are important ones in understanding inherited diseases, tumor progression and the challenges posed by pathogenic organisms.
The Neutral Theory of Molecular Evolution
Author: Motoo Kimura
Publisher: Cambridge University Press
ISBN: 1139935674
Category : Science
Languages : en
Pages : 388
Book Description
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
Publisher: Cambridge University Press
ISBN: 1139935674
Category : Science
Languages : en
Pages : 388
Book Description
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
Molecular Evolution and Phylogenetics
Author: Masatoshi Nei
Publisher: Oxford University Press
ISBN: 0199881227
Category : Science
Languages : en
Pages : 444
Book Description
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.
Publisher: Oxford University Press
ISBN: 0199881227
Category : Science
Languages : en
Pages : 444
Book Description
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.
Molecular Theory of the Living Cell
Author: Sungchul Ji
Publisher: Springer Science & Business Media
ISBN: 1461421527
Category : Science
Languages : en
Pages : 751
Book Description
The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine.
Publisher: Springer Science & Business Media
ISBN: 1461421527
Category : Science
Languages : en
Pages : 751
Book Description
The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine.
The Implicit Genome
Author: Lynn Helena Caporale
Publisher: Oxford University Press
ISBN: 0195346726
Category : Science
Languages : en
Pages : 398
Book Description
For over half a century, we have been in the thrall of the double-helicaln structure of DNA, which, in an instant, revealed that information can be transferred between generations by a simple rule, A pairs with T, G pairs with C. In its beautiful simplicity, this structure, along with the table of codons worked out in the following decade, had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. While we have learned much based on this assumption, there is much we have missed. Far from a passive tape running through a reader, genomes contain information that appears in new forms which create regions with distinct behavior. Some are "gene rich", some mobile, some full of repeats and duplications, some sticking together across long evolutionary distances, some readily breaking apart in tumor cells. Even protein-coding regions can carry additional information, taking advantage of the flexible coding options provided by the degeneracy of the genetic code. The chapters in this volume touch on one or more of three interconnected themes; information can be implied, rather than explicit, in a genome; information can lead to focused and/or regulated changes in nucleotide sequences; information that affects the probability of distinct classes of mutation has implications for evolutionary theory.
Publisher: Oxford University Press
ISBN: 0195346726
Category : Science
Languages : en
Pages : 398
Book Description
For over half a century, we have been in the thrall of the double-helicaln structure of DNA, which, in an instant, revealed that information can be transferred between generations by a simple rule, A pairs with T, G pairs with C. In its beautiful simplicity, this structure, along with the table of codons worked out in the following decade, had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. While we have learned much based on this assumption, there is much we have missed. Far from a passive tape running through a reader, genomes contain information that appears in new forms which create regions with distinct behavior. Some are "gene rich", some mobile, some full of repeats and duplications, some sticking together across long evolutionary distances, some readily breaking apart in tumor cells. Even protein-coding regions can carry additional information, taking advantage of the flexible coding options provided by the degeneracy of the genetic code. The chapters in this volume touch on one or more of three interconnected themes; information can be implied, rather than explicit, in a genome; information can lead to focused and/or regulated changes in nucleotide sequences; information that affects the probability of distinct classes of mutation has implications for evolutionary theory.