CRISPR-Cas Systems PDF Download
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Author: Rodolphe Barrangou
Publisher: Springer Science & Business Media
ISBN: 364234657X
Category : Science
Languages : en
Pages : 300
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Book Description
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Author: Rodolphe Barrangou
Publisher: Springer Science & Business Media
ISBN: 364234657X
Category : Science
Languages : en
Pages : 300
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Book Description
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Author: Steven M. Bachrach
Publisher: John Wiley & Sons
ISBN: 1118671228
Category : Science
Languages : en
Pages : 653
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Book Description
The Second Edition demonstrates how computational chemistry continues to shed new light on organic chemistry The Second Edition of author Steven Bachrach’s highly acclaimed Computational Organic Chemistry reflects the tremendous advances in computational methods since the publication of the First Edition, explaining how these advances have shaped our current understanding of organic chemistry. Readers familiar with the First Edition will discover new and revised material in all chapters, including new case studies and examples. There’s also a new chapter dedicated to computational enzymology that demonstrates how principles of quantum mechanics applied to organic reactions can be extended to biological systems. Computational Organic Chemistry covers a broad range of problems and challenges in organic chemistry where computational chemistry has played a significant role in developing new theories or where it has provided additional evidence to support experimentally derived insights. Readers do not have to be experts in quantum mechanics. The first chapter of the book introduces all of the major theoretical concepts and definitions of quantum mechanics followed by a chapter dedicated to computed spectral properties and structure identification. Next, the book covers: Fundamentals of organic chemistry Pericyclic reactions Diradicals and carbenes Organic reactions of anions Solution-phase organic chemistry Organic reaction dynamics The final chapter offers new computational approaches to understand enzymes. The book features interviews with preeminent computational chemists, underscoring the role of collaboration in developing new science. Three of these interviews are new to this edition. Readers interested in exploring individual topics in greater depth should turn to the book’s ancillary website www.comporgchem.com, which offers updates and supporting information. Plus, every cited article that is available in electronic form is listed with a link to the article.
Author:
Publisher: Academic Press
ISBN: 0128167610
Category : Science
Languages : en
Pages : 451
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Book Description
CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Updated release includes the latest information on the CRISPR-Cas Enzymes
Author: Stuart J. Hutchison
Publisher: Elsevier Health Sciences
ISBN: 1437703577
Category : Medical
Languages : en
Pages : 318
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Book Description
Principles of Vascular and Intravascular Ultrasound—a title in the Principles of Cardiovascular Imaging series—has everything you need to successfully obtain and interpret vascular ultrasound images. Stuart J. Hutchison—a premier cardiac imaging specialist—explains the dos and don’ts of ultrasound so you get the best images and avoid artifacts. Get only the coverage you need with clinically oriented, practical information presented in a consistent format that makes finding everything quick and easy. Focuses on clinically oriented and practical information so that you get only the coverage that you need. Explains how to obtain the best image quality and avoid artifacts through instructions on how to and how not to perform vascular ultrasound. Provides excellent visual guidance through high-quality images—many in color—that reinforce the quality of information in the text. Includes numerous tables with useful values and settings to help you master probe settings and measurements. Presents material in a consistent format that makes it easy to find information.
Author: Colin Sinnott
Publisher: Psychology Press
ISBN: 9780714651583
Category : History
Languages : en
Pages : 280
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Book Description
This work describes the vitl role of the Air Ministry in the development of the RAF's fighters and bombers before WWII.
Author:
Publisher:
ISBN:
Category : Law
Languages : en
Pages : 882
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Book Description
Author: Chris D. Geddes
Publisher: John Wiley & Sons
ISBN: 0470642785
Category : Science
Languages : en
Pages : 655
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Book Description
Discover how metal-enhanced fluorescence is changing traditional concepts of fluorescence This book collects and analyzes all the current trends, opinions, and emerging hot topics in the field of metal-enhanced fluorescence (MEF). Readers learn how this emerging technology enhances the utility of current fluorescence-based approaches. For example, MEF can be used to better detect and track specific molecules that may be present in very low quantities in either clinical samples or biological systems. Author Chris Geddes, a noted pioneer in the field, not only explains the fundamentals of metal-enhanced fluorescence, but also the significance of all the most recent findings and models in the field. Metal-enhanced fluorescence refers to the use of metal colloids and nanoscale metallic particles in fluorescence systems. It offers researchers the opportunity to modify the basic properties of fluorophores in both near- and far-field fluorescence formats. Benefits of metal-enhanced fluorescence compared to traditional fluorescence include: Increased efficiency of fluorescence emission Increased detection sensitivity Protect against fluorophore photobleaching Applicability to almost any molecule, including both intrinsic and extrinsic chromophores Following a discussion of the principles and fundamentals, the author examines the process and applications of metal-enhanced fluorescence. Throughout the book, references lead to the primary literature, facilitating in-depth investigations into particular topics. Guiding readers from the basics to state-of-the-technology applications, this book is recommended for all chemists, physicists, and biomedical engineers working in the field of fluorescence.
Author: Colin S Sinnott
Publisher: Routledge
ISBN: 1135278741
Category : History
Languages : en
Pages : 272
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Book Description
This work examines the evolution of the RAF's operational requirements for its home defence air force - for bombers to mount a deterrent counter offensive and for fighters to provide direct defence of Britain. It discusses the management processes, policies and decisions relevant to operational requirements on the basis of a detailed study of Air Ministry papers of the time. By tracing the development of operational requirements, the author exposes the thinking behind the RAF's quest for effective fighter and bomber aircraft. He describes the ideas and concepts of air warfare that were adopted in the 1920s, and shows how these evolved into the Air Staff's requirements for the aircraft which the RAF entered and fought in World War II.
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Publisher:
ISBN:
Category : Law reports, digests, etc
Languages : en
Pages : 688
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Book Description
Author: Reza Nazari
Publisher: Reza Nazari
ISBN: 1637194617
Category : Study Aids
Languages : en
Pages : 304
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Book Description
"Essential DCAS Grade 6 Math Study Guide: Empowering Students for Exam Success For parents and educators, equipping students with the right resources is crucial for their success. The DCAS Grade 6 Math Full Study Guide is tailored to support sixth graders gearing up for the DCAS math exam. This guide is a comprehensive tool, encompassing every aspect of the sixth-grade math curriculum, and is designed to prepare your child or students to face the exam with assurance and expertise. Guide Highlights: · Comprehensive Curriculum Overview: Offers a clear picture of the sixth-grade math curriculum, covering everything from basic arithmetic to the fundamentals of algebra and geometry. · Progressive Practice Questions: Features a variety of practice questions mirroring the DCAS exam format, arranged in ascending difficulty to monitor and support student progress. · In-Depth Solutions: Each practice problem is accompanied by a detailed solution, aiding in resolving doubts and strengthening student understanding. · Educational Strategies: Provides valuable tips for educators and parents on teaching students to tackle difficult questions, manage time effectively, and avoid common errors. · Interactive Learning Aids: Includes visual tools like infographics and diagrams, aiding in simplifying complex concepts. · Regular Assessment Tools: Contains review quizzes to gauge student understanding, identifying areas needing additional focus. The DCAS Grade 6 Math Full Study Guide transcends a mere textbook; it is a complete educational toolkit crafted for parents and educators. With this guide, you can equip your students with the necessary knowledge and skills to confidently navigate the DCAS math exam. Prepare your students for triumph, boost their confidence, and guide them towards academic excellence with this indispensable study guide."
