Cytoskeletal Mechanics PDF Download
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Author: Mohammad R. K. Mofrad
Publisher: Cambridge University Press
ISBN: 1139458108
Category : Science
Languages : en
Pages : 231
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Book Description
This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels. Studies reflect both the static, instantaneous nature of the structure, as well as its dynamic nature due to polymerization and the full array of biological processes. While it is unlikely that a single unifying approach will evolve from this diversity, it is the hope that a better appreciation of the various perspectives will lead to a highly coordinated approach to exploring the essential problems and better discussions among investigators with differing views.
Author: Mohammad R. K. Mofrad
Publisher: Cambridge University Press
ISBN: 1139458108
Category : Science
Languages : en
Pages : 231
Get Book Here
Book Description
This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels. Studies reflect both the static, instantaneous nature of the structure, as well as its dynamic nature due to polymerization and the full array of biological processes. While it is unlikely that a single unifying approach will evolve from this diversity, it is the hope that a better appreciation of the various perspectives will lead to a highly coordinated approach to exploring the essential problems and better discussions among investigators with differing views.
Author: Jonathon Howard
Publisher: Sinauer
ISBN: 9780878933334
Category : Science
Languages : en
Pages : 0
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Book Description
Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.
Author: Yuan Lin
Publisher: Frontiers Media SA
ISBN: 2889743667
Category : Science
Languages : en
Pages : 168
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Book Description
Author: Van C. Mow
Publisher: Springer Science & Business Media
ISBN: 1461384257
Category : Science
Languages : en
Pages : 571
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Book Description
Cell mechanics and cellular engineering may be defined as the application of principles and methods of engineering and life sciences toward fundamental understanding of structure-function relationships in normal and pathological cells and the development of biological substitutes to restore cellular functions. This definition is derived from one developed for tissue engineering at a 1988 NSF workshop. The reader of this volume will see the definition being applied and stretched to study cell and tissue structure-function relationships. The best way to define a field is really to let the investigators describe their areas of study. Perhaps cell mechanics could be compartmentalized by remembering how some of the earliest thinkers wrote about the effects of mechanics on growth. As early as 1638, Galileo hypothesized that gravity and of living mechanical forces place limits on the growth and architecture organisms. It seems only fitting that Robert Hooke, who gave us Hooke's law of elasticity, also gave us the word "cell" in his 1665 text, Micrographid, to designate these elementary entities of life. Julius Wolffs 1899 treatise on the function and form of the trabecular architecture provided an incisive example of the relationship between the structure of the body and the mechanical load it bears. In 1917, D' Arcy Thompson's On Growth and Form revolutionized the analysis of biological processes by introducing cogent physical explanations of the relationships between the structure and function of cells and organisms.
Author: Claudia Tanja Mierke
Publisher: Springer Nature
ISBN: 3030585328
Category : Science
Languages : en
Pages : 919
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Book Description
This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.
Author:
Publisher: Academic Press
ISBN: 0080856888
Category : Science
Languages : en
Pages : 451
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Book Description
Developing organisms are systems in which the geometry, dynamics, and boundary conditions are all changing in the course of morphogenesis. The morphogenesis of cells and organisms appear to be mediated in part by the mechanically active components of the cytoskeleton. Mechanical forces have long been considered secondary to the effects of molecular mechanisms in cell growth, differentiation, and development. This volume explores the role of mechanical forces in cell growth and development and demonstrates its importance. This volume will prove invaluable to all biologists interested in the fundamentals of mechanical forces in development, from the advanced to the graduate researcher.
Author:
Publisher: Academic Press
ISBN: 0123810108
Category : Science
Languages : en
Pages : 393
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Book Description
In recent years new discoveries have made this an exciting and important field of research. This exhaustive volume presents comprehensive chapters and detailed background information for researchers working with in the field of nuclear mechanics and genome regulation. - Both classic and state-of-the-art methods readily adaptable and designed to last the test of time - Relevant to clinicians and scientists working in a wide range of fields
Author: G.C. Sih
Publisher: Springer Science & Business Media
ISBN: 1402050623
Category : Science
Languages : en
Pages : 467
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Book Description
For the first time, a book is being edited to address how results from one scale can be shifted or related to another scale, say from macro to micro or vice versa. The new approach retains the use of the equilibrium mechanics within a scale level such that cross scale results can be connected by scale invariant criteria. Engineers in different disciplines should be able to understand and use the results.
Author: Yu-Li Wang
Publisher: Academic Press
ISBN: 0080548709
Category : Science
Languages : en
Pages : 629
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Book Description
Cell mechanics is the field of study that looks at how cells detect, modify, and respond to the physical properties of the cell environment. Cells communicate with each other through chemical and physical signals which are involved in a range of process from embryogenesis and wound healing to pathological conditions such as cancerous invasion. Similar principles are also likely to be critical for success in regenerative medicine. Cell mechanics is thus central to understanding these principles. As cell mechanics draws from the fields of biology, chemistry, physics, engineering, and mathematics, this book aims not only to provide a collection of research methods, but also to develop a common language among scientists who share the interest in cell mechanics but enter the field with diverse backgrounds. To this end all of the contributing authors have sought to explain in plain language the nature of the biological problems, the rationale for the approaches, in addition to the methods themselves. In addition, to balance practical utility against conceptual advances, Cell Mechanics has intentionally included both chapters that provide detailed recipes and those that emphasize basic principles. - Presents a distinctive emphasis on matrix mechanics and their interplay with cell functions - Includes highly significant topics relevant to basic and translational research, as well as tissue engineering - Emphasizes mechanical input and output of cells
Author: Amit Gefen
Publisher: Springer Science & Business Media
ISBN: 3642142184
Category : Technology & Engineering
Languages : en
Pages : 553
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Book Description
This book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads.
